当前位置: X-MOL 学术Exp. Neurobiol. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Drug Abuse and Psychosis: New Insights into Drug-induced Psychosis.
Experimental Neurobiology ( IF 2.4 ) Pub Date : 2017-02-07 , DOI: 10.5607/en.2017.26.1.11
Suji Ham 1 , Tae Kyoo Kim 2 , Sooyoung Chung 3 , Heh-In Im 4
Affiliation  

Addictive drug use or prescribed medicine abuse can cause psychosis. Some representative symptoms frequently elicited by patients with psychosis are hallucination, anhedonia, and disrupted executive functions. These psychoses are categorized into three classifications of symptoms: positive, negative, and cognitive. The symptoms of DIP are not different from the symptoms of schizophrenia, and it is difficult to distinguish between them. Due to this ambiguity of distinction between the DIP and schizophrenia, the DIP animal model has been frequently used as the schizophrenia animal model. However, although the symptoms may be the same, its causes are clearly different in that DIP is acquired and schizophrenia is heritable. Therefore, in this review, we cover several DIP models such as of amphetamine, PCP/ketamine, scopolamine, and LSD, and then we also address three schizophrenia models through a genetic approach with a new perspective that distinguishes DIP from schizophrenia.

中文翻译:

药物滥用和精神病:药物诱发的精神病的新见解。

上瘾的药物使用或处方药滥用会导致精神病。精神病患者经常引起的一些代表性症状是幻觉,快感不足和执行功能中断。这些精神病分为三类症状:积极,消极和认知。DIP的症状与精神分裂症的症状没有区别,并且很难区分。由于DIP和精神分裂症之间的这种歧义,DIP动物模型经常被用作精神分裂症动物模型。但是,尽管症状可能相同,但其原因明显不同,在于获得了DIP,并且精神分裂症是可遗传的。因此,在这篇评论中,我们涵盖了几种DIP模型,例如苯丙胺,PCP /氯胺酮,东pol碱和LSD,
更新日期:2020-08-21
down
wechat
bug