The critical role of commensal microbiota in the human body has been increasingly recognized, and our understanding of its implications in human health and disease has expanded rapidly. The lower respiratory tract contains diverse communities of microbes known as lung microbiota, which are present in healthy individuals and in individuals with respiratory diseases. The dysbiosis of the airway microbiota in pulmonary tuberculosis (TB) may play a role in the pathophysiological processes associated with TB disease. Recent studies of the lung microbiome have pointed out changes in lung microbial communities associated with TB and other lung diseases and have also begun to elucidate the profound effects that antituberculous drug therapy can have on the human lung microbiome composition. In this review, the potential role of the human microbiome in TB pathogenesis and the changes in the human microbiome with Mycobacterium tuberculosis infection and TB therapy are presented and discussed.

中文翻译：

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结核和抗结核治疗期间微生物组的变化。

共生菌群在人体中的关键作用已得到越来越多的认识，我们对它对人类健康和疾病的影响的理解也迅速扩大。下呼吸道包含多种多样的微生物群落，称为肺微生物群，存在于健康个体和患有呼吸系统疾病的个体中。肺结核（TB）中气道微生物群的失调可能在与TB疾病相关的病理生理过程中起作用。肺微生物组的最新研究指出了与结核病和其他肺部疾病有关的肺微生物群落的变化，并且也开始阐明抗结核药物疗法对人肺微生物组组成的深远影响。在这篇评论中，