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Transplantation of Autologous Bone Marrow Mesenchymal Stem Cells into the Testes of Infertile Male Rats and New Germ Cell Formation.
International Journal of Stem Cells ( IF 2.3 ) Pub Date : 2016-7-20 , DOI: 10.15283/ijsc16010
Mohammad Ghasemzadeh-Hasankolaei 1 , Roozali Batavani 2 , Mohamadreza Baghaban Eslaminejad 3 , Foroughazam Sayahpour 3
Affiliation  

Mesenchymal stem cells (MSCs), have been suggested as a potential choice for treatment of male infertility. Yet, the effects of MSCs on regeneration of germinal epithelium of seminiferous tubules and recovery of spermatogenesis have remained controversial. In this research, we have evaluated and compared the fate of autologous bone marrow (BM)-MSCs during three different periods of time- 4, 6 and 8 weeks after transplantation into the testes of busulfan-induced infertile male rats.

中文翻译:

将自体骨髓间充质干细胞移植到不育雄性大鼠的睾丸中并形成新的生殖细胞。

间充质干细胞 (MSCs) 已被建议作为治疗男性不育症的潜在选择。然而,MSCs对曲细精管生发上皮再生和精子发生恢复的影响仍存在争议。在这项研究中,我们评估和比较了自体骨髓 (BM)-MSCs 在移植到白消安诱导的不育雄性大鼠睾丸后 4、6 和 8 周三个不同时期的命运。
更新日期:2020-08-21
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