Adipose-derived mesenchymal stem cells (ADSCs) are promising candidates in regenerative medicine. The need for in vitro propagation to obtain therapeutic quantities of the cells imposes a risk of impaired functionality due to cellular senescence. The aim of the study was to analyze in vitro senescence of previously cryopreserved human ADSCs subjected to serial passages in cell culture.

中文翻译：

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培养扩增的人脂肪来源的间充质干细胞衰老的表征。

脂肪来源的间充质干细胞（ADSCs）是再生医学中有希望的候选者。需要体外繁殖以获得治疗量的细胞，由于细胞衰老，存在功能受损的风险。该研究的目的是分析先前低温保存的人ADSC在细胞培养中经历连续传代的体外衰老。