当前位置: X-MOL 学术Int. J. Stem Cells › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Stem Cells and Lung Regeneration.
International Journal of Stem Cells ( IF 2.3 ) Pub Date : 2016-7-19 , DOI: 10.15283/ijsc.2016.9.1.31
Mohammad K El-Badrawy 1 , Nesrein M Shalabi 1 , Mie A Mohamed 2 , Amany Ragab 1 , Heba Wagih Abdelwahab 1
Affiliation  

Tissues such as the lung, liver, and pancreas that have a low steady-state cell turnover yet can respond robustly after injury to replace damaged cells. The airway epithelium is exposed to inhaled particles and pathogens that may lead to the development of a many infectious and inflammatory respiratory diseases. Lung transplantation is an accepted modality of treatment for end-stage lung diseases. Since the early 1990 s, more than 26,000 lung transplants have been performed at centers worldwide. However, the availability of donor tissues and organs is limited, which presents a serious limitation for widespread transplantation surgery. The appearance of bioengineered lung and tracheal tissue transplants is considered a promising alternative to the classical transplantation of donor organ/tissue. Stem cells therapy arises as a new therapeutic approach, with a wide application potential.

中文翻译:

干细胞和肺再生。

具有低稳态细胞更新率的组织(如肺,肝和胰腺)在受伤后可以强有力地响应以替换受损的细胞。气道上皮暴露于吸入的颗粒和病原体中,这些病原体可能导致许多传染性和炎性呼吸系统疾病的发展。肺移植是终末期肺部疾病的公认治疗方式。自1990年代初以来,全世界的中心已进行了超过26,000例肺移植。然而,供体组织和器官的可用性受到限制,这对广泛的移植手术提出了严重的限制。生物工程化的肺和气管组织移植的出现被认为是供体器官/组织经典移植的有前途的替代方法。
更新日期:2020-08-21
down
wechat
bug