Sensing clinically relevant biomolecules is crucial for the detection and prevention of disease. Currently used detection methods tend to be expensive, time intensive, and specific for only one particular biomolecule of interest. Nanoparticle-based arrays using conjugated polymers have emerged as an analytical and potential clinical tool, allowing detection of a wide range of biomolecules using selective, not specific, sensor components. In this report, we highlight recent progress in nanoparticle - polymer sensor arrays in both the fundamental understanding of how the sensor arrays function as well as the detection of clinically relevant bacteria and cells.

中文翻译：

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聚合物 – 用于基于阵列的传感的纳米粒子组件

感知临床相关的生物分子对于疾病的检测和预防至关重要。目前使用的检测方法往往昂贵、耗时，并且仅针对一种特定的感兴趣的生物分子具有特异性。使用共轭聚合物的基于纳米颗粒的阵列已成为一种分析和潜在的临床工具，允许使用选择性而非特定的传感器组件检测范围广泛的生物分子。在本报告中，我们重点介绍了纳米颗粒 - 聚合物传感器阵列在对传感器阵列如何工作的基本理解以及临床相关细菌和细胞检测方面的最新进展。