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Materials that harness and modulate the immune system.
MRS Bulletin ( IF 5 ) Pub Date : 2014-01-01 , DOI: 10.1557/mrs.2013.310
Jamal S Lewis 1 , Krishnendu Roy 2 , Benjamin G Keselowsky 3
Affiliation  

Recently, biomaterial scientists have married materials engineering and immunobiology to conceptualize new immunomodulatory materials. This special class of biomaterials can modulate and harness the innate properties of immune functionality for enhanced therapeutic efficacy. Generally, two fundamental strategies are followed in the design of immunomodulatory biomaterials: (1) immuno-evasive (immuno-mimetic, immuno-suppressing, or immuno-inert) biomaterials and (2) immuno-activating or immuno-enhancing biomaterials. This article highlights the development and application of a number of immunomodulatory materials, categorized by these two general approaches.

中文翻译:

利用和调节免疫系统的材料。

最近,生物材料科学家将材料工程和免疫生物学结合起来,以概念化新的免疫调节材料。这类特殊的生物材料可以调节和利用免疫功能的固有特性,从而提高治疗效果。通常,在免疫调节生物材料的设计中遵循两种基本策略:(1)免疫逃避(免疫模拟,免疫抑制或免疫惰性)生物材料,和(2)免疫激活或免疫增强生物材料。本文重点介绍了按这两种一般方法分类的多种免疫调节材料的开发和应用。
更新日期:2019-11-01
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