Herpesviral mRNAs are produced and translated by cellular machinery, rendering them susceptible to the network of regulatory events that impact translation. In response, these viruses have evolved to infiltrate and hijack translational control pathways as well as to integrate specialized host translation strategies into their own repertoire. They are robust systems to dissect mechanisms of mammalian translational regulation and continue to offer insight into cis-acting mRNA features that impact assembly and activity of the translation apparatus. Here, I discuss recent advances revealing the extent to which the three herpesvirus subfamilies regulate both host and viral translation, thereby dramatically impacting the landscape of protein synthesis in infected cells.

中文翻译：

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疱疹病毒感染过程中翻译环境的调节。

疱疹病毒mRNA由细胞机制产生和翻译，使其易受影响翻译的调节事件网络的影响。作为响应，这些病毒已经进化为渗透和劫持翻译控制途径，以及将专门的宿主翻译策略整合到自己的库中。它们是剖析哺乳动物翻译调控机制的强大系统，并继续深入研究影响翻译装置装配和活性的顺式mRNA功能。在这里，我讨论了最近的进展，揭示了三个疱疹病毒亚家族调节宿主和病毒翻译的程度，从而极大地影响了受感染细胞中蛋白质合成的格局。