The antidepressant and sleep-promoting effects of light exposure might be useful for treating age-related mood and sleep disorders. In view of recent evidence suggesting beneficial effects of morning light, this study examined the associations of mood and sleep with morning light exposure, 24 h environmental illumination, and the degree to which the volunteers’ bedroom windows were covered in the morning. We examined 459 postmenopausal women participating an ancillary study of the Women’s Health Initiative conducted at the University of California, San Diego Clinical Center, San Diego, CA, USA. At baseline, volunteers completed a 4-week sleep-recall questionnaire. Volunteers were then assessed for 5–7 days in their home environments with actigraphic wrist monitors. During home recording, self-reported mood was assessed. Morning illumination during the first 4 h after arising, 24-h illumination mesor (cosine-fitted mean), and illumination acrophase (cosine-fitted peak time) were calculated. Sleep was scored each night using validated wrist actigraphic methods. A sleep diary was completed each morning. During two 24-h periods, urine was collected approximately every 2 h during wakefulness and following any voidings during the sleep period. Cosine-fitting established the acrophase of urinary 6-sulfatoxymelatonin (aMT6s) excretion. Morning illumination and 24-h illumination were modestly associated with better mood and sleep. Associations of light with mood and sleep were consistently greater for subjects whose body clocks were delayed relative to the group median. Less morning window covering in the subjects’ bedrooms was associated with more morning light and less depressed mood. The results suggest that both morning and 24-h light exposure may be beneficial for older adults.

中文翻译：

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绝经后妇女晨间照明和窗帘与情绪和睡眠的关联

光照的抗抑郁和睡眠促进作用可能有助于治疗与年龄相关的情绪和睡眠障碍。鉴于最近的证据表明晨光有益，本研究调查了情绪和睡眠与晨光照射、24 小时环境照明以及志愿者卧室窗户在早晨被遮住的程度之间的关联。我们检查了 459 名参与在美国加利福尼亚州圣地亚哥加利福尼亚大学圣地亚哥临床中心进行的妇女健康倡议辅助研究的绝经后妇女。在基线时，志愿者完成了一份为期 4 周的睡眠回忆问卷。然后，志愿者在他们的家庭环境中使用活动记录手腕监视器进行了 5-7 天的评估。在家庭录音期间，评估了自我报告的情绪。计算起床后前 4 小时的早晨光照、24 小时光照中间值（余弦拟合平均值）和光照末期（余弦拟合峰值时间）。使用经过验证的手腕活动记录方法对每晚的睡眠进行评分。每天早上完成一份睡眠日记。在两个 24 小时期间，在清醒期间和睡眠期间排尿后大约每 2 小时收集一次尿液。余弦拟合建立了尿 6-硫酸酯氧基褪黑激素 (aMT6s) 排泄的高峰期。早晨照明和 24 小时照明与更好的情绪和睡眠适度相关。对于生物钟相对于组中位数延迟的受试者而言，光线与情绪和睡眠的关联始终更大。受试者卧室的早晨窗帘较少与更多的晨光和较少的抑郁情绪有关。结果表明，早晨和 24 小时光照可能对老年人有益。