Menopause in the female life cycle is a special period due to important hormonal, physical and psychological changes. Sleep disruption represents a common complaint for midlife and menopausal women, related to primary sleep disorders, including insomnia, sleep disordered breathing, restless legs syndrome (RLS), mood and anxiety disorder, other medical illness, hormonal-related vasomotor symptoms, and aging per se. Aims of our study were to evaluate the prevalence of sleep disorders in a sample of pre and post menopausal women, and to investigate the relationship between sleep and other medical disorders, and life habits. Among workers in the six participant centers, we enrolled 334 women, aged between 40 and 60 years, that completed a questionnaire that included screening on menarche, menstrual cycle, fertility, parity, menopause, life habits, personal medical and sleep history and related treatment, and self-administered scales for sleep quality (PSQI), excessive daytime sleepiness [Epworth Sleepiness Scale (ESS)], mood disorder [Beck Depression Inventory (BDI)], Berlin Questionnaire for sleep disordered breathing (SDB), IRLS diagnostic interview and Rating Scale. Menopausal and perimenopausal women showed an increased prevalence of poor sleep, high risk of SDB, and mood disorder; menopausal women also reported increased RLS severity. Mood disorder had a significant impact on night sleep measures and excessive daytime sleepiness, as well as on RLS severity, and had a greater prevalence in hypertensive women. Sleep disturbances are frequent in menopausal women. Their aetiology is unclear, but probably multifactorial, and many factors contribute to the sleep disruption. Our data suggest the importance of correctly investigate and address sleep problems associated with menopause, through sleep history, and a sleep study could be obtained if clinically warranted. Pharmacological and behavioural treatment strategies should then be aimed at improving sleep and life quality in perimenopausal and menopausal women.

中文翻译：

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更年期的睡眠障碍：意大利一项多中心研究的结果。

由于荷尔蒙，身体和心理的重要变化，女性生命周期中的更年期是一个特殊的时期。睡眠中断是中年和绝经期妇女的常见病，与原发性睡眠障碍有关，包括失眠，睡眠呼吸障碍，不安腿综合征（RLS），情绪和焦虑症，其他内科疾病，与荷尔蒙有关的血管舒缩症状以及每se。我们研究的目的是评估绝经前后妇女的睡眠障碍患病率，并调查睡眠与其他医学障碍与生活习惯之间的关系。在这六个参与中心的工作人员中，我们招募了334名年龄在40至60岁之间的妇女，这些妇女完成了一份调查表，包括初潮，月经周期，生育能力，均等，更年期，生活习惯，个人医疗和睡眠史及相关治疗，以及自我管理的睡眠质量量表（PSQI），白天过度嗜睡[Epworth嗜睡量表（ESS）]，情绪障碍[贝克抑郁量表（BDI）]，柏林睡眠呼吸障碍问卷（SDB），IRLS诊断访谈和评分量表。绝经和围绝经期妇女的睡眠不足，SDB的高风险和情绪障碍的患病率增加。绝经期妇女还报告了RLS严重程度增加。情绪障碍对夜间睡眠措施和白天过度嗜睡以及RLS严重程度有重大影响，并且在高血压妇女中患病率更高。绝经期妇女经常有睡眠障碍。他们的病因尚不清楚，但可能是多因素的，许多因素导致睡眠中断。我们的数据表明，通过睡眠史正确调查和解决与更年期有关的睡眠问题非常重要，并且如果临床需要可以进行睡眠研究。药物和行为治疗策略应旨在改善围绝经期和绝经期妇女的睡眠和生活质量。