Human chorionic plate-derived mesenchymal stem cells (CP-MSCs) isolated from the placenta have been reported to demonstrate therapeutic effects in animal models of liver injury; however, the underlying epigenetic mechanism of this effect has not been elucidated. Thus, we investigated whether CP-MSCs influence epigenetic processes during regeneration of the injured liver.

中文翻译：

---

IL-6 / STAT3信号通过胎盘干细胞的表观遗传学改变在CCl4诱导的肝损伤大鼠模型中促进肝再生。

据报道，从胎盘中分离出的人绒毛膜板间充质干细胞（CP-MSCs）在动物肝损伤模型中显示出治疗作用。但是，尚未阐明这种作用的潜在表观遗传机制。因此，我们调查了CP-MSC是否在受伤肝脏的再生过程中影响表观遗传过程。