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The adult environment promotes the transcriptional maturation of human iPSC-derived muscle grafts npj Regen. Med. (IF 7.2) Pub Date : 2024-04-04 Sarah B. Crist, Karim Azzag, James Kiley, Ilsa Coleman, Alessandro Magli, Rita C. R. Perlingeiro
Pluripotent stem cell (PSC)-based cell therapy is an attractive option for the treatment of multiple human disorders, including muscular dystrophies. While in vitro differentiating PSCs can generate large numbers of human lineage-specific tissue, multiple studies evidenced that these cell populations mostly display embryonic/fetal features. We previously demonstrated that transplantation of PSC-derived
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A two-way street – cellular metabolism and myofibroblast contraction npj Regen. Med. (IF 7.2) Pub Date : 2024-04-03 Anne Noom, Birgit Sawitzki, Petra Knaus, Georg N. Duda
Tissue fibrosis is characterised by the high-energy consumption associated with myofibroblast contraction. Although myofibroblast contraction relies on ATP production, the role of cellular metabolism in myofibroblast contraction has not yet been elucidated. Studies have so far only focused on myofibroblast contraction regulators, such as integrin receptors, TGF-β and their shared transcription factor
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Comparison studies identify mesenchymal stromal cells with potent regenerative activity in osteoarthritis treatment npj Regen. Med. (IF 7.2) Pub Date : 2024-04-01 Hongshang Chu, Shaoyang Zhang, Zhenlin Zhang, Hua Yue, Huijuan Liu, Baojie Li, Feng Yin
Osteoarthritis affects 15% of people over 65 years of age. It is characterized by articular cartilage degradation and inflammation, leading to joint pain and disability. Osteoarthritis is incurable and the patients may eventually need joint replacement. An emerging treatment is mesenchymal stromal cells (MSCs), with over two hundred clinical trials being registered. However, the outcomes of these trials
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Intrinsic and extrinsic actions of human neural progenitors with SUFU inhibition promote tissue repair and functional recovery from severe spinal cord injury npj Regen. Med. (IF 7.2) Pub Date : 2024-03-22 Yong-Long Chen, Xiang-Lan Feng, Kin-Wai Tam, Chao-Yang Fan, May Pui-Lai Cheung, Yong-Ting Yang, Stanley Wong, Daisy Kwok-Yan Shum, Ying-Shing Chan, Chi-Wai Cheung, Martin Cheung, Jessica Aijia Liu
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Multichannel bridges and NSC synergize to enhance axon regeneration, myelination, synaptic reconnection, and recovery after SCI npj Regen. Med. (IF 7.2) Pub Date : 2024-03-18 Usha Nekanti, Pooja S. Sakthivel, Atena Zahedi, Dana A. Creasman, Rebecca A. Nishi, Courtney M. Dumont, Katja M. Piltti, Glenn L. Guardamondo, Norbert Hernandez, Xingyuan Chen, Hui Song, Xiaoxiao Lin, Joshua Martinez, Lillian On, Anita Lakatos, Kiran Pawar, Brian T. David, Zhiling Guo, Stephanie K. Seidlits, Xiangmin Xu, Lonnie D. Shea, Brian J. Cummings, Aileen J. Anderson
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Inflammation-suppressing cornea-in-a-syringe with anti-viral GF19 peptide promotes regeneration in HSV-1 infected rabbit corneas npj Regen. Med. (IF 7.2) Pub Date : 2024-03-01 Egidijus Simoliunas, Inés Ruedas-Torres, Yolanda Jiménez-Gómez, Elle Edin, Mozhgan Aghajanzadeh-Kiyaseh, Mostafa Zamani-Roudbaraki, Rimvydas Asoklis, Milda Alksne, Neethi C. Thathapudi, Bijay K. Poudel, Ieva Rinkunaite, Kasparas Asoklis, Monika Iesmantaite, Laura Ortega-Llamas, Almantas Makselis, Marcelo Munoz, Daiva Baltriukiene, Virginija Bukelskiene, Jaime Gómez-Laguna, Miguel González-Andrades
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Denervation alters the secretome of myofibers and thereby affects muscle stem cell lineage progression and functionality npj Regen. Med. (IF 7.2) Pub Date : 2024-03-01 Henriette Henze, Sören S. Hüttner, Philipp Koch, Svenja C. Schüler, Marco Groth, Björn von Eyss, Julia von Maltzahn
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Biological study of skin wound treated with Alginate/Carboxymethyl cellulose/chorion membrane, diopside nanoparticles, and Botox A npj Regen. Med. (IF 7.2) Pub Date : 2024-02-27 Naimeh Mahheidari, Mohammad Kamalabadi-Farahani, Mohammad Reza Nourani, Amir Atashi, Morteza Alizadeh, Niloofar Aldaghi, Majid Salehi
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Skeletal muscle regeneration after extensive cryoinjury of caudal myomeres in adult zebrafish npj Regen. Med. (IF 7.2) Pub Date : 2024-02-20 Hendrik Oudhoff, Vincent Hisler, Florian Baumgartner, Lana Rees, Dogan Grepper, Anna Jaźwińska
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Matrix-bound nanovesicle-associated IL-33 supports functional recovery after skeletal muscle injury by initiating a pro-regenerative macrophage phenotypic transition npj Regen. Med. (IF 7.2) Pub Date : 2024-01-27 J. G. Bartolacci, M. N. Behun, J. P. Warunek, T. Li, A. Sahu, G. K. Dwyer, A. Lucas, J. Rong, F. Ambrosio, H. R. Turnquist, S. F. Badylak
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hUC-MSCs-derived MFGE8 ameliorates locomotor dysfunction via inhibition of ITGB3/ NF-κB signaling in an NMO mouse model npj Regen. Med. (IF 7.2) Pub Date : 2024-01-20 Huiming Xu, Wei Jiang, Xuejia Li, Jiaohua Jiang, Shabbir Khan Afridi, Longhui Deng, Rui Li, Ermei Luo, Zhaoqing Zhang, Yu-Wen Alvin Huang, Yaxiong Cui, Kwok-Fai So, Haijia Chen, Wei Qiu, Changyong Tang
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MSCs mediate long-term efficacy in a Crohn’s disease model by sustained anti-inflammatory macrophage programming via efferocytosis npj Regen. Med. (IF 7.2) Pub Date : 2024-01-20 Maneesh Dave, Atul Dev, Rodrigo A. Somoza, Nan Zhao, Satish Viswanath, Pooja Rani Mina, Prathyush Chirra, Verena Carola Obmann, Ganapati H. Mahabeleshwar, Paola Menghini, Blythe Durbin-Johnson, Jan Nolta, Christopher Soto, Abdullah Osme, Lam T. Khuat, William J. Murphy, Arnold I. Caplan, Fabio Cominelli
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Engineered extracellular vesicle-encapsulated CHIP as novel nanotherapeutics for treatment of renal fibrosis npj Regen. Med. (IF 7.2) Pub Date : 2024-01-13 Cheng Ji, Jiahui Zhang, Linru Shi, Hui Shi, Wenrong Xu, Jianhua Jin, Hui Qian
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Airway epithelial cell identity and plasticity are constrained by Sox2 during lung homeostasis, tissue regeneration, and in human disease npj Regen. Med. (IF 7.2) Pub Date : 2024-01-05 Kazushige Shiraishi, Michael P. Morley, Dakota L. Jones, Gan Zhao, Aaron I. Weiner, Maria C. Basil, Edward Cantu, Laura T. Ferguson, Michele Oyster, Apoorva Babu, Yun Ying, Su Zhou, Shanru Li, Andrew E. Vaughan, Edward E. Morrisey
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Myeloid cell-associated aromatic amino acid metabolism facilitates CNS myelin regeneration npj Regen. Med. (IF 7.2) Pub Date : 2024-01-02 Jingwen Hu, George S. Melchor, Dimitrios Ladakis, Joan Reger, Hee Won Kim, Kelly A. Chamberlain, Nataliia V. Shults, Helena C. Oft, Victoria N. Smith, Lauren M. Rosko, Erqiu Li, Maryna Baydyuk, Meng-Meng Fu, Pavan Bhargava, Jeffrey K. Huang
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Effective protection of photoreceptors using an inflammation-responsive hydrogel to attenuate outer retinal degeneration npj Regen. Med. (IF 7.2) Pub Date : 2023-12-14 Hyerim Kim, Hyeonhee Roh, Sang-Heon Kim, Kangwon Lee, Maesoon Im, Seung Ja Oh
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Type I collagen and fibromodulin enhance the tenogenic phenotype of hASCs and their potential for tendon regeneration npj Regen. Med. (IF 7.2) Pub Date : 2023-12-14 Tian Tu, Yuan Shi, Boya Zhou, Xiaoyu Wang, Wenjie Zhang, Guangdong Zhou, Xiumei Mo, Wenbo Wang, Jinglei Wu, Wei Liu
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Harnessing bioengineered myeloid progenitors for precision immunotherapies npj Regen. Med. (IF 7.2) Pub Date : 2023-12-12 Willem Buys, Elias T. Zambidis
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Epidermal–dermal coupled spheroids are important for tissue pattern regeneration in reconstituted skin explant cultures npj Regen. Med. (IF 7.2) Pub Date : 2023-11-23 Mingxing Lei, Jingwei Jiang, Mengyue Wang, Wang Wu, Jinwei Zhang, Wanqian Liu, Wei Zhou, Yung-Chih Lai, Ting-Xin Jiang, Randall B. Widelitz, Hans I-Chen Harn, Li Yang, Cheng-Ming Chuong
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Aryl hydrocarbon receptor regulates IL-22 receptor expression on thymic epithelial cell and accelerates thymus regeneration npj Regen. Med. (IF 7.2) Pub Date : 2023-11-08 Jingyi Shen, Ying Wang, Fei Zheng, Shuo Cao, Qiu Lan, Kailin Xu, Bin Pan
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Mfap4: a promising target for enhanced liver regeneration and chronic liver disease treatment npj Regen. Med. (IF 7.2) Pub Date : 2023-11-07 Viktoriia Iakovleva, Anna Wuestefeld, Agnes Bee Leng Ong, Rong Gao, Neslihan Arife Kaya, May Yin Lee, Weiwei Zhai, Wai Leong Tam, Yock Young Dan, Torsten Wuestefeld
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Topical application of synthetic melanin promotes tissue repair npj Regen. Med. (IF 7.2) Pub Date : 2023-11-02 Dauren Biyashev, Zofia E. Siwicka, Ummiye V. Onay, Michael Demczuk, Dan Xu, Madison K. Ernst, Spencer T. Evans, Cuong V. Nguyen, Florencia A. Son, Navjit K. Paul, Naneki C. McCallum, Omar K. Farha, Stephen D. Miller, Nathan C. Gianneschi, Kurt Q. Lu
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Local decorin delivery via hyaluronic acid microrods improves cardiac performance, ventricular remodeling after myocardial infarction npj Regen. Med. (IF 7.2) Pub Date : 2023-10-23 Priya Mohindra, Justin X. Zhong, Qizhi Fang, Darnell L. Cuylear, Cindy Huynh, Huiliang Qiu, Dongwei Gao, Bhushan N. Kharbikar, Xiao Huang, Matthew L. Springer, Randall J. Lee, Tejal A. Desai
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Repair of osteochondral defects: efficacy of a tissue-engineered hybrid implant containing both human MSC and human iPSC-cartilaginous particles npj Regen. Med. (IF 7.2) Pub Date : 2023-10-19 Shinichi Nakagawa, Wataru Ando, Kazunori Shimomura, David A. Hart, Hiroto Hanai, George Jacob, Ryota Chijimatsu, Seido Yarimitu, Hiromichi Fujie, Seiji Okada, Noriyuki Tsumaki, Norimasa Nakamura
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Epimorphic regeneration in the mammalian tympanic membrane npj Regen. Med. (IF 7.2) Pub Date : 2023-10-18 Sonia M. Scaria, Stacey M. Frumm, Ellee P. Vikram, Sarah A. Easow, Amar H. Sheth, Eliah R. Shamir, Shengyang Kevin Yu, Aaron D. Tward
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Enhanced peripheral nerve regeneration by mechano-electrical stimulation npj Regen. Med. (IF 7.2) Pub Date : 2023-10-17 Youyi Tai, Thamidul Islam Tonmoy, Shwe Win, Natasha T. Brinkley, B. Hyle Park, Jin Nam
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Alkaline shear-thinning micro-nanocomposite hydrogels initiate endogenous TGFβ signaling for in situ bone regeneration npj Regen. Med. (IF 7.2) Pub Date : 2023-10-13 Yuting Niu, Zhen Yang, Yang Yang, Xu Wang, Ping Zhang, Longwei Lv, Sainan Wang, Yan Liu, Yunsong Liu, Yongsheng Zhou
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Human retinal ganglion cell neurons generated by synchronous BMP inhibition and transcription factor mediated reprogramming npj Regen. Med. (IF 7.2) Pub Date : 2023-09-29 Devansh Agarwal, Nicholas Dash, Kevin W. Mazo, Manan Chopra, Maria P. Avila, Amit Patel, Ryan M. Wong, Cairang Jia, Hope Do, Jie Cheng, Colette Chiang, Shawna L. Jurlina, Mona Roshan, Michael W. Perry, Jong M. Rho, Risa Broyer, Cassidy D. Lee, Robert N. Weinreb, Cezar Gavrilovici, Nicholas W. Oesch, Derek S. Welsbie, Karl J. Wahlin
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An engineered periosteum for efficient delivery of rhBMP-2 and mesenchymal progenitor cells during bone regeneration npj Regen. Med. (IF 7.2) Pub Date : 2023-09-29 Juan Antonio Romero-Torrecilla, José María Lamo-Espinosa, Purificación Ripalda-Cemboráin, Tania López-Martínez, Gloria Abizanda, Luis Riera-Álvarez, Sergio Ruiz de Galarreta-Moriones, Asier López-Barberena, Naiara Rodríguez-Flórez, Reyes Elizalde, Vineetha Jayawarna, José Valdés-Fernández, Miguel Echanove-González de Anleo, Peter Childs, Elena de Juan-Pardo, Manuel Salmeron-Sanchez, Felipe Prósper
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Immunomodulatory contribution of mast cells to the regenerative biomaterial microenvironment npj Regen. Med. (IF 7.2) Pub Date : 2023-09-20 Raymond M. Wang, Joshua M. Mesfin, Maria Karkanitsa, Jessica L. Ungerleider, Emma Zelus, Yuxue Zhang, Yu Kawakami, Yuko Kawakami, Toshiaki Kawakami, Karen L. Christman
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Ligament injury in adult zebrafish triggers ECM remodeling and cell dedifferentiation for scar-free regeneration npj Regen. Med. (IF 7.2) Pub Date : 2023-09-19 Troy Anderson, Julia Mo, Ernesto Gagarin, Desmarie Sherwood, Maria Blumenkrantz, Eric Mao, Gianna Leon, Hailey Levitz, Hung-Jhen Chen, Kuo-Chang Tseng, Peter Fabian, J. Gage Crump, Joanna Smeeton
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Endogenous tenocyte activation underlies the regenerative capacity of the adult zebrafish tendon npj Regen. Med. (IF 7.2) Pub Date : 2023-09-19 Stephanie L. Tsai, Steffany Villaseñor, Rishita R. Shah, Jenna L. Galloway
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Local BMP2 hydrogel therapy for robust bone regeneration in a porcine model of Legg-Calvé-Perthes disease npj Regen. Med. (IF 7.2) Pub Date : 2023-09-14 Chi Ma, Min Sung Park, Felipe Alves do Monte, Vishal Gokani, Olumide O. Aruwajoye, Yinshi Ren, Xiaohua Liu, Harry K. W. Kim
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Topically-applied collagen-binding serum albumin-fused interleukin-4 modulates wound microenvironment in non-healing wounds npj Regen. Med. (IF 7.2) Pub Date : 2023-09-11 Abigail L. Lauterbach, Rachel P. Wallace, Aaron T. Alpar, Kirsten C. Refvik, Joseph W. Reda, Ako Ishihara, Taryn N. Beckman, Anna J. Slezak, Yukari Mizukami, Aslan Mansurov, Suzana Gomes, Jun Ishihara, Jeffrey A. Hubbell
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Opposing roles for TGFβ- and BMP-signaling during nascent alveolar differentiation in the developing human lung npj Regen. Med. (IF 7.2) Pub Date : 2023-09-09 Tristan Frum, Peggy P. Hsu, Renee F. C. Hein, Ansley S. Conchola, Charles J. Zhang, Olivia R. Utter, Abhinav Anand, Yi Zhang, Sydney G. Clark, Ian Glass, Jonathan Z. Sexton, Jason R. Spence
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Ferric citrate and apo-transferrin enable erythroblast maturation with β-globin from hemogenic endothelium npj Regen. Med. (IF 7.2) Pub Date : 2023-08-25 Soo-Been Jeon, Hyebin Koh, A-Reum Han, Jieun Kim, Sunghun Lee, Jae-Ho Lee, Seung-Soon Im, Young-sup Yoon, Jong-Hee Lee, Ji Yoon Lee
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Combination human umbilical cord perivascular and endothelial colony forming cell therapy for ischemic cardiac injury npj Regen. Med. (IF 7.2) Pub Date : 2023-08-25 Farwah Iqbal, Alexander Johnston, Brandon Wyse, Razieh Rabani, Poonam Mander, Banafshe Hoseini, Jun Wu, Ren-Ke Li, Andrée Gauthier-Fisher, Peter Szaraz, Clifford Librach
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Engineered inhaled nanocatalytic therapy for ischemic cerebrovascular disease by inducing autophagy of abnormal mitochondria npj Regen. Med. (IF 7.2) Pub Date : 2023-08-11 Deping Wang, Bowen Li, Shuchao Wang, Yingjian Hao, Hua Wang, Wei Sun, Jimin Cao, Xin Zhou, Bin Zheng
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Transgene-free direct conversion of murine fibroblasts into functional muscle stem cells npj Regen. Med. (IF 7.2) Pub Date : 2023-08-08 Xhem Qabrati, Inseon Kim, Adhideb Ghosh, Nicola Bundschuh, Falko Noé, Andrew S. Palmer, Ori Bar-Nur
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Author Correction: The bright side of fibroblasts: molecular signature and regenerative cues in major organs. npj Regen. Med. (IF 7.2) Pub Date : 2023-08-07 Rita N Gomes,Filipa Manuel,Diana S Nascimento
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Functional ProTracer identifies patterns of cell proliferation in tissues and underlying regulatory mechanisms npj Regen. Med. (IF 7.2) Pub Date : 2023-08-03 Xiuxiu Liu, Maoying Han, Wendong Weng, Yan Li, Wenjuan Pu, Kuo Liu, Xufeng Li, Lingjuan He, Ruilin Sun, Ruling Shen, Yulong He, Dandan Liang, Yi-Han Chen, Qing-Dong Wang, Jan S. Tchorz, Bin Zhou
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A postnatal network of co-hepato/pancreatic stem/progenitors in the biliary trees of pigs and humans npj Regen. Med. (IF 7.2) Pub Date : 2023-08-01 Wencheng Zhang, Xicheng Wang, Giacomo Lanzoni, Eliane Wauthier, Sean Simpson, Jennifer Ashley Ezzell, Amanda Allen, Carolyn Suitt, Jonah Krolik, Alexander Jhirad, Juan Dominguez-Bendala, Vincenzo Cardinale, Domenico Alvaro, Diletta Overi, Eugenio Gaudio, Praveen Sethupathy, Guido Carpino, Christopher Adin, Jorge A Piedrahita, Kyle Mathews, Zhiying He, Lola McAdams Reid
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LRRC10 regulates mammalian cardiomyocyte cell cycle during heart regeneration npj Regen. Med. (IF 7.2) Pub Date : 2023-07-28 Rebecca J. Salamon, Megan C. McKeon, Jiyoung Bae, Xiaoya Zhang, Wyatt G. Paltzer, Kayla N. Wanless, Alyssa R. Schuett, Dakota J. Nuttall, Stephen A. Nemr, Rupa Sridharan, Youngsook Lee, Timothy J. Kamp, Ahmed I. Mahmoud
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3D printing titanium grid scaffold facilitates osteogenesis in mandibular segmental defects npj Regen. Med. (IF 7.2) Pub Date : 2023-07-24 Yongfeng Li, Huawei Liu, Chao Wang, Rongzeng Yan, Lei Xiang, Xiaodan Mu, Lingling Zheng, Changkui Liu, Min Hu
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MAP4Ks inhibition promotes retinal neuron regeneration from Müller glia in adult mice npj Regen. Med. (IF 7.2) Pub Date : 2023-07-13 Houjian Zhang, Yuli Guo, Yaqiong Yang, Yuqian Wang, Youwen Zhang, Jingbin Zhuang, Yuting Zhang, Mei Shen, Jiankai Zhao, Rongrong Zhang, Yan Qiu, Shiying Li, Jiaoyue Hu, Wei Li, Jianfeng Wu, Haiwei Xu, Steven J. Fliesler, Yi Liao, Zuguo Liu
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Regeneration of tracheal neotissue in partially decellularized scaffolds npj Regen. Med. (IF 7.2) Pub Date : 2023-07-12 Zheng Hong Tan, Sayali Dharmadhikari, Lumei Liu, Jane Yu, Kimberly M. Shontz, Jacob T. Stack, Christopher K. Breuer, Susan D. Reynolds, Tendy Chiang
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Macrophage-based therapy for intervertebral disc herniation: preclinical proof-of-concept npj Regen. Med. (IF 7.2) Pub Date : 2023-07-10 Cláudia Ribeiro-Machado, Susana G. Santos, Inês A. Amaral, Joana Caldeira, Paulo Pereira, Mário A. Barbosa, Carla Cunha
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Nerve growth factor receptor (Ngfr) induces neurogenic plasticity by suppressing reactive astroglial Lcn2/Slc22a17 signaling in Alzheimer’s disease npj Regen. Med. (IF 7.2) Pub Date : 2023-07-10 Tohid Siddiqui, Mehmet Ilyas Cosacak, Stanislava Popova, Prabesh Bhattarai, Elanur Yilmaz, Annie J. Lee, Yuhao Min, Xue Wang, Mariet Allen, Özkan İş, Zeynep Tansu Atasavum, Natalia Rodriguez-Muela, Badri N. Vardarajan, Delaney Flaherty, Andrew F. Teich, Ismael Santa-Maria, Uwe Freudenberg, Carsten Werner, Giuseppe Tosto, Richard Mayeux, Nilüfer Ertekin-Taner, Caghan Kizil
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Thermosensitive and antioxidant wound dressings capable of adaptively regulating TGFβ pathways promote diabetic wound healing npj Regen. Med. (IF 7.2) Pub Date : 2023-07-08 Hong Niu, Ya Guan, Ting Zhong, Liang Ma, Mohamed Zayed, Jianjun Guan
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A short dasatinib and quercetin treatment is sufficient to reinstate potent adult neuroregenesis in the aged killifish npj Regen. Med. (IF 7.2) Pub Date : 2023-06-16 Jolien Van houcke, Valerie Mariën, Caroline Zandecki, Rajagopal Ayana, Elise Pepermans, Kurt Boonen, Eve Seuntjens, Geert Baggerman, Lutgarde Arckens
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The one-step fabrication of porous hASC-laden GelMa constructs using a handheld printing system npj Regen. Med. (IF 7.2) Pub Date : 2023-06-10 SeoYul Jo, JiUn Lee, Hyeongjin Lee, Dongryeol Ryu, GeunHyung Kim
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DNA methyltransferase 1 deficiency improves macrophage motility and wound healing by ameliorating cholesterol accumulation npj Regen. Med. (IF 7.2) Pub Date : 2023-06-08 Chuanrong Zhao, Qianru Yang, Runze Tang, Wang Li, Jin Wang, Fangfang Yang, Jianan Zhao, Juanjuan Zhu, Wei Pang, Ning Li, Xu Zhang, Xiao Yu Tian, Weijuan Yao, Jing Zhou
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Janus porous polylactic acid membranes with versatile metal–phenolic interface for biomimetic periodontal bone regeneration npj Regen. Med. (IF 7.2) Pub Date : 2023-06-03 Yaping Zhang, Yi Chen, Tian Ding, Yandi Zhang, Daiwei Yang, Yajun Zhao, Jin Liu, Baojin Ma, Alberto Bianco, Shaohua Ge, Jianhua Li
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Cerebral organoids transplantation repairs infarcted cortex and restores impaired function after stroke npj Regen. Med. (IF 7.2) Pub Date : 2023-05-30 Shi-Ying Cao, Di Yang, Zhen-Quan Huang, Yu-Hui Lin, Hai-Yin Wu, Lei Chang, Chun-Xia Luo, Yun Xu, Yan Liu, Dong-Ya Zhu
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Pluripotent stem cell-derived committed cardiac progenitors remuscularize damaged ischemic hearts and improve their function in pigs npj Regen. Med. (IF 7.2) Pub Date : 2023-05-26 Lynn Yap, Li Yen Chong, Clarissa Tan, Swarnaseetha Adusumalli, Millie Seow, Jing Guo, Zuhua Cai, Sze Jie Loo, Eric Lim, Ru San Tan, Elina Grishina, Poh Loong Soong, Narayan Lath, Lei Ye, Enrico Petretto, Karl Tryggvason
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A superior extracellular matrix binding motif to enhance the regenerative activity and safety of therapeutic proteins npj Regen. Med. (IF 7.2) Pub Date : 2023-05-22 Yasmin K. Alshoubaki, Yen-Zhen Lu, Julien M. D. Legrand, Rezvan Karami, Mathilde Fossat, Ekaterina Salimova, Ziad Julier, Mikaël M. Martino
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Macrophages maintain mammary stem cell activity and mammary homeostasis via TNF-α-PI3K-Cdk1/Cyclin B1 axis npj Regen. Med. (IF 7.2) Pub Date : 2023-05-02 Yu Zhou, Zi Ye, Wei Wei, Mengna Zhang, Fujing Huang, Jinpeng Li, Cheguo Cai
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Rational engineering of lung alveolar epithelium npj Regen. Med. (IF 7.2) Pub Date : 2023-04-28 Katherine L. Leiby, Yifan Yuan, Ronald Ng, Micha Sam Brickman Raredon, Taylor S. Adams, Pavlina Baevova, Allison M. Greaney, Karen K. Hirschi, Stuart G. Campbell, Naftali Kaminski, Erica L. Herzog, Laura E. Niklason
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Endothelial Brg1 fine-tunes Notch signaling during zebrafish heart regeneration npj Regen. Med. (IF 7.2) Pub Date : 2023-04-07 Chenglu Xiao, Junjie Hou, Fang Wang, Yabing Song, Jiyuan Zheng, Lingfei Luo, Jianbin Wang, Wanqiu Ding, Xiaojun Zhu, Jing-Wei Xiong
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The MRN complex maintains the biliary-derived hepatocytes in liver regeneration through ATR-Chk1 pathway npj Regen. Med. (IF 7.2) Pub Date : 2023-04-06 Jingmei Song, Jianlong Ma, Xing Liu, Zhuofu Huang, Lianghui Li, Linke Li, Lingfei Luo, Rui Ni, Jianbo He