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Improving diagnostic accuracy of identifying gastric cancer patients with peritoneal metastases: tumor-guided cell-free DNA analysis of peritoneal fluid Oncogene (IF 8.0) Pub Date : 2024-04-23 Karen van der Sluis, Johanna W. van Sandick, Marieke A. Vollebergh, Jolanda M. van Dieren, Niek Hugen, Koen J. Hartemink, Alexander A. F. A. Veenhof, Els Verhoeven, José G. van den Berg, Petur Snaebjornsson, Michael Noe, Tom van Wezel, Mirjam C. Boelens, Liudmila L. Kodach
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VEGF-induced Nrdp1 deficiency in vascular endothelial cells promotes cancer metastasis by degrading vascular basement membrane Oncogene (IF 8.0) Pub Date : 2024-04-23 Qing-Qing Li, Meng Guo, Guang-Huan He, Kai-Hua Xi, Mei-Yi Zhou, Rong-Yi Shi, Guo-Qiang Chen
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ZBTB16 inhibits DNA replication and induces cell cycle arrest by targeting WDHD1 transcription in lung adenocarcinoma Oncogene (IF 8.0) Pub Date : 2024-04-23 Kai Wang, Deyu Guo, Tao Yan, Shijie Sun, Yadong Wang, Haotian Zheng, Guanghui Wang, Jiajun Du
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P4HA2 activates mTOR via hydroxylation and targeting P4HA2-mTOR inhibits lung adenocarcinoma cell growth Oncogene (IF 8.0) Pub Date : 2024-04-23 Ersuo Jin, Shengjie Wang, Donglai Chen, Jia-Ping Wang, Yuanyuan Zeng, Runfeng Sun, Hong-Tao Zhang
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Identification of genes that promote PI3K pathway activation and prostate tumour formation Oncogene (IF 8.0) Pub Date : 2024-04-23 Jeffrey C. Francis, Amy Capper, Alistair G. Rust, Klea Ferro, Jian Ning, Wei Yuan, Johann de Bono, Stephen J. Pettitt, Amanda Swain
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KLF5 regulates actin remodeling to enhance the metastasis of nasopharyngeal carcinoma Oncogene (IF 8.0) Pub Date : 2024-04-22 Zhenyu Yang, Yanfu Peng, Yaqin Wang, Panyang Yang, Zhuohui Huang, Tingqiu Quan, Xudong Xu, Peng Sun, Ying Sun, Jiawei Lv, Denghui Wei, Guan-Qun Zhou
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ULK1-dependent phosphorylation of PKM2 antagonizes O-GlcNAcylation and regulates the Warburg effect in breast cancer Oncogene (IF 8.0) Pub Date : 2024-04-17 Zibin Zhou, Xiyuan Zheng, Jianxin Zhao, Aiyun Yuan, Zhuan Lv, Guangcan Shao, Bin Peng, Meng-Qiu Dong, Quan Xu, Xingzhi Xu, Jing Li
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Inherited KDM6AA649T facilitates tumor-immune escape and exacerbates colorectal signet-ring cell carcinoma outcomes Oncogene (IF 8.0) Pub Date : 2024-04-15 Maoxiao Feng, Chengwei Chai, Xiaodong Hao, Xiaojiang Lai, Yuanyuan Luo, Hong Zhang, Wenzhu Tang, Ningxin Gao, Guihong Pan, Xiaojie Liu, Yunshan Wang, Wenjing Xiong, Qiang Wu, Jun Wang
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COL5A1 promotes triple-negative breast cancer progression by activating tumor cell-macrophage crosstalk Oncogene (IF 8.0) Pub Date : 2024-04-12 Xi Chen, Chenao Ma, Yaming Li, Yiran Liang, Tong Chen, Dianwen Han, Dan Luo, Ning Zhang, Wenjing Zhao, Lijuan Wang, Qifeng Yang
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LPCAT2 inhibits colorectal cancer progression via the PRMT1/SLC7A11 axis Oncogene (IF 8.0) Pub Date : 2024-04-11 Nan Cao, Fangmei Zhang, Jiang Yin, Jianlei Zhang, Xiqing Bian, Guopei Zheng, Nan Li, Ying Lin, Liyun Luo
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NRF2 activation by cysteine as a survival mechanism for triple-negative breast cancer cells Oncogene (IF 8.0) Pub Date : 2024-04-10 Laura Bottoni, Alberto Minetti, Giulia Realini, Elena Pio, Daniela Giustarini, Ranieri Rossi, Chiara Rocchio, Lorenzo Franci, Laura Salvini, Orazio Catona, Romina D’Aurizio, Mahdi Rasa, Emanuele Giurisato, Francesco Neri, Maurizio Orlandini, Mario Chiariello, Federico Galvagni
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Transcription factor ZIC2 regulates the tumorigenic phenotypes associated with both bulk and cancer stem cells in epithelial ovarian cancer Oncogene (IF 8.0) Pub Date : 2024-04-09 Huachen Chen, Laura Jiyoung Lee, Krista M. Vincent, Zhihua Xu, Jiahui Liu, Guihua Zhang, Zorica Nakevska, DuPreez Smith, Cheng-Han Lee, Lynne-Marie Postovit, YangXin Fu
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FAK-LINC01089 negative regulatory loop controls chemoresistance and progression of small cell lung cancer Oncogene (IF 8.0) Pub Date : 2024-04-09 Xianteng Wang, Xingkai Li, Liman Niu, Fang Lv, Ting Guo, Yushun Gao, Yuliang Ran, Weiren Huang, Bing Wang
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Bone marrow stromal cells dictate lanosterol biosynthesis and ferroptosis of multiple myeloma Oncogene (IF 8.0) Pub Date : 2024-04-09 Hongmei Jiang, Lijuan Wang, Qiguo Zhang, Sheng Wang, Linchuang Jia, Hao Cheng, Jingya Wang, Xin Li, Ying Xie, Yixuan Wang, Meilin Hu, Jing Guo, Qian Li, Ziyi Peng, Mengqi Wang, Yangyang Xie, Tiantian Li, Yafei Wang, Bill D. Geng, Sundararaman Swaminathan, P. Leif Bergsagel, Zhiqiang Liu
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PDIA2 has a dual function in promoting androgen deprivation therapy induced venous thrombosis events and castrate resistant prostate cancer progression Oncogene (IF 8.0) Pub Date : 2024-04-08 Yinan Li, Lei Lv, Meng Ye, Ning Xie, Ladan Fazli, Yuli Wang, Weilun Wang, Shuofei Yang, Qihong Ni, Jiaquan Chen, Xiangjiang Guo, Yiping Zhao, Guanhua Xue, Jianjun Sha, Xuesen Dong, Lan Zhang
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The role of human 5-Lipoxygenase (5-LO) in carcinogenesis - a question of canonical and non-canonical functions Oncogene (IF 8.0) Pub Date : 2024-04-04 Astrid S. Kahnt, Ann-Kathrin Häfner, Dieter Steinhilber
5-Lipoxygenase (5-LO), a fatty acid oxygenase, is the central enzyme in leukotriene (LT) biosynthesis, potent arachidonic acid-derived lipid mediators released by innate immune cells, that control inflammatory and allergic responses. In addition, through interaction with 12- and 15-lipoxgenases, the enzyme is involved in the formation of omega-3 fatty acid-based oxylipins, which are thought to be involved
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Inactivation of kindlin-3 increases human melanoma aggressiveness through the collagen-activated tyrosine kinase receptor DDR1 Oncogene (IF 8.0) Pub Date : 2024-04-03 Coralie Reger De Moura, Baptiste Louveau, Fanélie Jouenne, Paul Vilquin, Maxime Battistella, Yaelle Bellahsen-Harrar, Aurélie Sadoux, Suzanne Menashi, Nicolas Dumaz, Céleste Lebbé, Samia Mourah
The role of the focal adhesion protein kindlin-3 as a tumor suppressor and its interaction mechanisms with extracellular matrix constitute a major field of investigation to better decipher tumor progression. Besides the well-described role of kindlin-3 in integrin activation, evidence regarding modulatory functions between melanoma cells and tumor microenvironment are lacking and data are needed to
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The lincRNA JUNI regulates the stress-dependent induction of c-Jun, cellular migration and survival through the modulation of the DUSP14-JNK axis Oncogene (IF 8.0) Pub Date : 2024-04-02 Vikash Kumar, Xavier Sabaté-Cadenas, Isha Soni, Esther Stern, Carine Vias, Doron Ginsberg, Carlos Romá-Mateo, Rafael Pulido, Martin Dodel, Faraz K. Mardakheh, Alena Shkumatava, Eitan Shaulian
Cancer cells employ adaptive mechanisms to survive various stressors, including genotoxic drugs. Understanding the factors promoting survival is crucial for developing effective treatments. In this study, we unveil a previously unexplored long non-coding RNA, JUNI (JUN-DT, LINC01135), which is upregulated by genotoxic drugs through the activation of stress-activated MAPKs, JNK, and p38 and consequently
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USP26 promotes colorectal cancer tumorigenesis by restraining PRKN-mediated mitophagy Oncogene (IF 8.0) Pub Date : 2024-04-02 Qi Wu, Zhihong Wang, Siqi Chen, Xiaowei She, Shengyu Zhu, Pengcheng Li, Lang Liu, Chongchong Zhao, Kangdi Li, Anyi Liu, Changsheng Huang, Yaqi Chen, Fuqing Hu, Guihua Wang, Junbo Hu
Deubiquitinating enzymes (DUBs) are promising targets for cancer therapy because of their pivotal roles in various physiological and pathological processes. Among these, ubiquitin-specific peptidase 26 (USP26) is a protease with crucial regulatory functions. Our study sheds light on the upregulation of USP26 in colorectal cancer (CRC), in which its increased expression correlates with an unfavorable
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An integrated ceRNA network identifies miR-375 as an upregulated miRNA playing a tumor suppressive role in aggressive prostate cancer Oncogene (IF 8.0) Pub Date : 2024-04-02 Mengjie Chen, Cheng Zou, Yu Tian, Wenchao Li, Yingying Li, Dingxiao Zhang
Prostate cancer (PCa) remains a significant cause of morbidity and mortality among men worldwide. A number of genes have been implicated in prostate tumorigenesis, but the mechanisms underlying their dysregulation are still incompletely understood. Evidence has established the competing endogenous RNA (ceRNA) theory as a novel regulatory mechanism for post-transcriptional alterations. Yet, a comprehensive
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The splicing factor WBP11 mediates MCM7 intron retention to promote the malignant progression of ovarian cancer Oncogene (IF 8.0) Pub Date : 2024-04-01 Yuan Wei, Zhongshao Chen, Yingwei Li, Kun Song
Accumulating studies suggest that splicing factors play important roles in many diseases including human cancers. Our study revealed that WBP11, a core splicing factor, is highly expressed in ovarian cancer (OC) tissues and associated with a poor prognosis. WBP11 inhibition significantly impaired the proliferation and mobility of ovarian cancer cells in vitro and in vivo. Furthermore, FOXM1 transcriptionally
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ScRNA-seq of gastric cancer tissues reveals differences in the immune microenvironment of primary tumors and metastases Oncogene (IF 8.0) Pub Date : 2024-03-30 Yu Dong, Keshu Hu, Jiayu Zhang, Mengxuan Zhu, Mengling Liu, Yitao Yuan, Xun Sun, Zhenghang Xu, Suyao Li, Yanjing Zhu, Chi Zhang, Pengfei Zhang, Tianshu Liu
Gastric carcinoma (GC) is regarded as one of the deadliest cancer characterized by diversity and haste metastasis and suffers limited understanding of the spatial variation between primary and metastatic GC tumors. In this project, transcriptome analysis on 46 primary tumorous, adjacent non-tumorous, and metastatic GC tissues was performed. The results demonstrated that metastatic tumorous tissues
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Targeting STING elicits GSDMD-dependent pyroptosis and boosts anti-tumor immunity in renal cell carcinoma Oncogene (IF 8.0) Pub Date : 2024-03-28 Shengpan Wu, Baojun Wang, Hongzhao Li, Hanfeng Wang, Songliang Du, Xing Huang, Yang Fan, Yu Gao, Liangyou Gu, Qingbo Huang, Jianjun Chen, Xu Zhang, Yan Huang, Xin Ma
While Stimulator-of-interferon genes (STING) is an innate immune adapter cruicial for sensing cytosolic DNA and modulating immune microenvironment, its tumor-promoting role in tumor survival and immune evasion remains largely unknown. Here we reported that renal cancer cells are exceptionally dependent on STING for survival and evading immunosurveillance via suppressing ER stress-mediated pyroptosis
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SC912 inhibits AR-V7 activity in castration-resistant prostate cancer by targeting the androgen receptor N-terminal domain Oncogene (IF 8.0) Pub Date : 2024-03-26 Qianhui Yi, Xiaojun Han, Henry G. Yu, Huei-Yu Chen, Dinghong Qiu, Jie Su, Rongtuan Lin, Gerald Batist, Jian Hui Wu
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RNF126-mediated ubiquitination of FSP1 affects its subcellular localization and ferroptosis Oncogene (IF 8.0) Pub Date : 2024-03-21 Wanqun Xie, Jiajia Wang, Shuaiwei Tian, Heng Zhao, Liangliang Cao, Zhuangzhuang Liang, Jian Yang, Yang Zhao, Baocheng Wang, Feng Jiang, Jie Ma
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ZEB1 controls a lineage-specific transcriptional program essential for melanoma cell state transitions Oncogene (IF 8.0) Pub Date : 2024-03-22 Simon Durand, Yaqi Tang, Roxane M. Pommier, Valentin Benboubker, Maxime Grimont, Felix Boivin, Laetitia Barbollat-Boutrand, Eric Cumunel, Florian Dupeuble, Anaïs Eberhardt, Maud Plaschka, Stéphane Dalle, Julie Caramel
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Colorectal cancer cells secreting DKK4 transform fibroblasts to promote tumour metastasis Oncogene (IF 8.0) Pub Date : 2024-03-22 Xue Li, Yulin Chen, Ran Lu, Min Hu, Lei Gu, Qiaorong Huang, Wentong Meng, Hongyan Zhu, Chuanwen Fan, Zongguang Zhou, Xianming Mo
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Loss of RNA-binding protein CELF2 promotes acute leukemia development via FAT10-mTORC1 Oncogene (IF 8.0) Pub Date : 2024-03-21 Tengxiao Guo, Yuxia Wang, Xiaolu Sun, Shuaibing Hou, Yanjie Lan, Shengnan Yuan, Shuang Yang, Fei Zhao, Yajing Chu, Yuanwu Ma, Tao Cheng, Jia Yu, Bing Liu, Weiping Yuan, Xiaomin Wang
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E-cadherin interacts with EGFR resulting in hyper-activation of ERK in multiple models of breast cancer Oncogene (IF 8.0) Pub Date : 2024-03-20 Gabriella C. Russo, Ashleigh J. Crawford, David Clark, Julie Cui, Ryan Carney, Michelle N. Karl, Boyang Su, Bartholomew Starich, Tung-Shing Lih, Pratik Kamat, Qiming Zhang, Praful R. Nair, Pei-Hsun Wu, Meng-Horng Lee, Hon S. Leong, Hui Zhang, Vito W. Rebecca, Denis Wirtz
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DHODH inhibition represents a therapeutic strategy and improves abiraterone treatment in castration-resistant prostate cancer Oncogene (IF 8.0) Pub Date : 2024-03-13 Shaoqiang Guo, Miaomiao Miao, Yufeng Wu, Dongyue Pan, Qinyan Wu, Zhanfang Kang, Jianwen Zeng, Guoping Zhong, Chengfei Liu, Junjian Wang
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p53 modulates kinase inhibitor resistance and lineage plasticity in NF1-related MPNSTs Oncogene (IF 8.0) Pub Date : 2024-03-13 Jamie L. Grit, Lauren E. McGee, Elizabeth A. Tovar, Curt J. Essenburg, Emily Wolfrum, Ian Beddows, Kaitlin Williams, Rachael T. C. Sheridan, Joshua L. Schipper, Marie Adams, Menusha Arumugam, Thomas Vander Woude, Sharavana Gurunathan, Jeffrey M. Field, Julia Wulfkuhle, Emanuel F. Petricoin, Carrie R. Graveel, Matthew R. Steensma
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Neutrophils in cancer: dual roles through intercellular interactions Oncogene (IF 8.0) Pub Date : 2024-03-12 Xinyu Yu, Changhui Li, Zijin Wang, Yaping Xu, Shiqun Shao, Fangwei Shao, Hua Wang, Jian Liu
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A novel bioinformatic approach reveals cooperation between Cancer/Testis genes in basal-like breast tumors Oncogene (IF 8.0) Pub Date : 2024-03-11 Marthe Laisné, Brianna Rodgers, Sarah Benlamara, Julien Wicinski, André Nicolas, Lounes Djerroudi, Nikhil Gupta, Laure Ferry, Olivier Kirsh, Diana Daher, Claude Philippe, Yuki Okada, Emmanuelle Charafe-Jauffret, Gael Cristofari, Didier Meseure, Anne Vincent-Salomon, Christophe Ginestier, Pierre-Antoine Defossez
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Downregulation of UBB potentiates SP1/VEGFA-dependent angiogenesis in clear cell renal cell carcinoma Oncogene (IF 8.0) Pub Date : 2024-03-11 Jinpeng Wang, Enyang Zhao, Bo Geng, Wei Zhang, Zhuolun Li, Qing Liu, Weiyang Liu, Wenfu Zhang, Wenbin Hou, Nan Zhang, Zhiming Liu, Bosen You, Pengfei Wu, Xuedong Li
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Single-cell landscape of undifferentiated pleomorphic sarcoma Oncogene (IF 8.0) Pub Date : 2024-03-08 Yifei Lu, Deqian Chen, Bingnan Wang, Wenjun Chai, Mingxia Yan, Yong Chen, Yong Zhan, Ran Yang, Enqing Zhou, Shuyang Dai, Yi Li, Rui Dong, Biqiang Zheng
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In vivo genome-wide CRISPR screening identifies CITED2 as a driver of prostate cancer bone metastasis Oncogene (IF 8.0) Pub Date : 2024-03-07 Juan M. Arriaga, Kacey Ronaldson-Bouchard, Florencia Picech, Francisca Nunes de Almeida, Stephanie Afari, Houssein Chhouri, Gordana Vunjak-Novakovic, Cory Abate-Shen
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Exosomal lncRNA XIST promotes perineural invasion of pancreatic cancer cells via miR-211-5p/GDNF Oncogene (IF 8.0) Pub Date : 2024-03-07 Ke Cheng, Jinjin Pan, Qinlong Liu, Yuke Ji, Liang Liu, Xiangqian Guo, Qiang Wang, Shao Li, Jinyue Sun, Miaomiao Gong, Ying Zhang, Yuhui Yuan
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N6-methyladenosine demethyltransferase FTO mediated m6A modification of estrogen receptor alpha in non-small cell lung cancer tumorigenesis Oncogene (IF 8.0) Pub Date : 2024-03-05 Xin Xu, Shiyu Qiu, Bingjie Zeng, Yiwen Huang, Xianzhao Wang, Fusheng Li, Yiran Yang, Leiqun Cao, Xiao Zhang, Jiayi Wang, Lifang Ma
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tiRNA-Val-CAC-2 interacts with FUBP1 to promote pancreatic cancer metastasis by activating c‑MYC transcription Oncogene (IF 8.0) Pub Date : 2024-03-05 Qunli Xiong, Yaguang Zhang, Yongfeng Xu, Yang Yang, Zhiwei Zhang, Ying Zhou, Su Zhang, Lian Zhou, Xiaowen Wan, Xiaojuan Yang, Zhu Zeng, Jinlu Liu, Ying Zheng, Junhong Han, Qing Zhu
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CDK9-55 guides the anaphase-promoting complex/cyclosome (APC/C) in choosing the DNA repair pathway choice Oncogene (IF 8.0) Pub Date : 2024-03-04 Luigi Alfano, Carmelina Antonella Iannuzzi, Daniela Barone, Iris Maria Forte, Maria Carmen Ragosta, Maria Cuomo, Giulio Mazzarotti, Milena Dell’Aquila, Angela Altieri, Antonella Caporaso, Cristin Roma, Laura Marra, Silvia Boffo, Paola Indovina, Michelino De Laurentiis, Antonio Giordano
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LINC00460-FUS-MYC feedback loop drives breast cancer metastasis and doxorubicin resistance Oncogene (IF 8.0) Pub Date : 2024-02-28 Leiyan Yang, Miaomiao Wang, Ya Wang, Yong Zhu, Jiarui Wang, Mingming Wu, Qianying Guo, Xinghua Han, Vijay Pandey, Zhengsheng Wu, Peter E. Lobie, Tao Zhu
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TWIST1 is a critical downstream target of the HGF/MET pathway and is required for MET driven acquired resistance in oncogene driven lung cancer Oncogene (IF 8.0) Pub Date : 2024-03-01 Vinod Kumar, Zachary A. Yochum, Princey Devadassan, Eric H.-B. Huang, Ethan Miller, Roja Baruwal, Purva H. Rumde, Autumn L. GaitherDavis, Laura P. Stabile, Timothy F. Burns
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Targeting the IRE1α-XBP1s axis confers selective vulnerability in hepatocellular carcinoma with activated Wnt signaling Oncogene (IF 8.0) Pub Date : 2024-02-28 Tingting Zhang, Faming Zhao, Yi Zhang, Ji-Hua Shi, Fengzhen Cui, Weixiang Ma, Kai Wang, Chuanrui Xu, Qingping Zeng, Rong Zhong, Ningning Li, Yong Liu, Yang Jin, Xia Sheng
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Fulvestrant and everolimus efficacy after CDK4/6 inhibitor: a prospective study with circulating tumor DNA analysis Oncogene (IF 8.0) Pub Date : 2024-02-27 Antoine Vasseur, Luc Cabel, Caroline Hego, Wissam Takka, Olfa Trabelsi Grati, Benjamin Renouf, Florence Lerebours, Delphine Loirat, Etienne Brain, Paul Cottu, Marie-Paule Sablin, Jean-Yves Pierga, Céline Callens, Shufang Renault, François-Clément Bidard
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Spontaneous expression of the CIC::DUX4 fusion oncoprotein from a conditional allele potently drives sarcoma formation in genetically engineered mice Oncogene (IF 8.0) Pub Date : 2024-02-27 Peter G. Hendrickson, Kristianne M. Oristian, MaKenna R. Browne, Lixia Luo, Yan Ma, Diana M. Cardona, Joshua O. Nash, Pedro L. Ballester, Scott Davidson, Adam Shlien, Corinne M. Linardic, David G. Kirsch
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Ubiquitin specific peptidase 38 epigenetically regulates KLF transcription factor 5 to augment malignant progression of lung adenocarcinoma Oncogene (IF 8.0) Pub Date : 2024-02-26 Tao Zhang, Fei Su, Bofang Wang, Lixin Liu, Yongbin Lu, Hongxin Su, Ruijiang Ling, Peng Yue, Huanyu Dai, Tianning Yang, Jingru Yang, Rui Chen, Ruiyue Wu, Kaili Zhu, Da Zhao, Xiaoming Hou
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Dissecting the oncogenic properties of essential RNA-modifying enzymes: a focus on NAT10 Oncogene (IF 8.0) Pub Date : 2024-02-26 Mahmood H. Dalhat, Sharath Narayan, Hannah Serio, Daniel Arango
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AF1q is a universal marker of neuroblastoma that sustains N-Myc expression and drives tumorigenesis Oncogene (IF 8.0) Pub Date : 2024-02-27 Babak Oskouian, Joanna Y. Lee, Shahab Asgharzadeh, Ranjha Khan, Meng Zhang, Julia R. Weisbrod, Youn-Jeong Choi, Latika Puri, Ana E. Aguilar, Piming Zhao, Julie D. Saba
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Robustness of cancer microbiome signals over a broad range of methodological variation Oncogene (IF 8.0) Pub Date : 2024-02-23 Gregory D. Sepich-Poore, Daniel McDonald, Evguenia Kopylova, Caitlin Guccione, Qiyun Zhu, George Austin, Carolina Carpenter, Serena Fraraccio, Stephen Wandro, Tomasz Kosciolek, Stefan Janssen, Jessica L. Metcalf, Se Jin Song, Jad Kanbar, Sandrine Miller-Montgomery, Robert Heaton, Rana Mckay, Sandip Pravin Patel, Austin D. Swafford, Tal Korem, Rob Knight
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miR-147b mediated suppression of DUSP8 promotes lung cancer progression Oncogene (IF 8.0) Pub Date : 2024-02-23 Kati Turkowski, Frederik Herzberg, Stefan Günther, Andreas Weigert, Tamara Haselbauer, Ludger Fink, David Brunn, Friedrich Grimminger, Werner Seeger, Holger Sültmann, Thorsten Stiewe, Soni S. Pullamsetti, Rajkumar Savai
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O-GlcNAcylation of E3 ubiquitin ligase SKP2 promotes hepatocellular carcinoma proliferation Oncogene (IF 8.0) Pub Date : 2024-02-23 Zhongqi Feng, Jiaxin Yin, Zhirong Zhang, Zhen Chen, Luyi Huang, Ni Tang, Kai Wang
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SIRT7: a novel molecular target for personalized cancer treatment? Oncogene (IF 8.0) Pub Date : 2024-02-21 Alessandro Ianni, Poonam Kumari, Shahriar Tarighi, Thomas Braun, Alejandro Vaquero
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Loss of EIF4G2 mediates aggressiveness in distinct human endometrial cancer subpopulations with poor survival outcome in patients Oncogene (IF 8.0) Pub Date : 2024-02-22 Sara Meril, Maya Muhlbauer Avni, Chen Lior, Marcela Bahlsen, Tsviya Olender, Alon Savidor, Judit Krausz, Hila Belhanes Peled, Hila Birisi, Nofar David, Shani Bialik, Ruth Scherz-Shouval, Yehuda Ben David, Adi Kimchi
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Cancer-associated fibroblasts rewire the estrogen receptor response in luminal breast cancer, enabling estrogen independence Oncogene (IF 8.0) Pub Date : 2024-02-22 Steven E. Reid, Jessica Pantaleo, Paulina Bolivar, Matteo Bocci, Jonas Sjölund, Mikkel Morsing, Eugenia Cordero, Sara Larsson, Maria Malmberg, Brinton Seashore-Ludlow, Kristian Pietras
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The BAP1 nuclear deubiquitinase is involved in the nonhomologous end-joining pathway of double-strand DNA repair through interaction with DNA-PK Oncogene (IF 8.0) Pub Date : 2024-02-21 Hiroki Sato, Tatsuo Ito, Takuo Hayashi, Shigehisa Kitano, Hediye Erdjument-Bromage, Matthew J. Bott, Shinichi Toyooka, Marjorie Zauderer, Marc Ladanyi
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METTL3-mediated m6A modification of lncRNA TSPAN12 promotes metastasis of hepatocellular carcinoma through SENP1-depentent deSUMOylation of EIF3I Oncogene (IF 8.0) Pub Date : 2024-02-19 Bei Li, Xianze Xiong, Jianrong Xu, Dingzhong Peng, Guilin Nie, Ningyuan Wen, Yaoqun Wang, Jiong Lu
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Flotillin-1 palmitoylation is essential for its stability and subsequent tumor promoting capabilities Oncogene (IF 8.0) Pub Date : 2024-02-19 Bryan McClellan, Crystal N. Wilson, Andrew J. Brenner, Christopher A. Jolly, Linda deGraffenried
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CircUSP1 as a novel marker promotes gastric cancer progression via stabilizing HuR to upregulate USP1 and Vimentin Oncogene (IF 8.0) Pub Date : 2024-02-16 Rong Li, Junyi Wang, Zhenfan Xie, Xinyu Tian, Jie Hou, Dongli Wang, Hui Qian, Han Shen, Wenrong Xu
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LncRNA PRBC induces autophagy to promote breast cancer progression through modulating PABPC1-mediated mRNA stabilization Oncogene (IF 8.0) Pub Date : 2024-02-16 Yiran Liang, Bing Chen, Fanchao Xu, Li Long, Fangzhou Ye, Yajie Wang, Dan Luo, Yaming Li, Wenjing Zhao, Lijuan Wang, Yuhan Jin, Lei Wang, Xiaoli Kong, Peng Su, Qifeng Yang
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RNA-sequencing predicts a role of androgen receptor and aldehyde dehydrogenase 1A1 in osteosarcoma lung metastases Oncogene (IF 8.0) Pub Date : 2024-02-15 Tanya E. Heim, Margaret L. Hankins, Rebekah Belayneh, Nerone Douglas, Vu Dinh, Murali Kovvur, David N. Boone, Vrutika Ukani, Sumail Bhogal, Vaidehi Patel, Taylor M. A. Moniz, Kelly M. Bailey, Ivy John, Karen Schoedel, Kurt R. Weiss, Rebecca J. Watters