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Mayo ClinicThe WHu Lab in the Biochemistry and Molecular Biology Department招聘博士后(Independent lab in the USA)
研究方向
分子生物学/免疫学、RNA Biology
招聘岗位
职位亮点
Independent research opportunity in the USA
背景要求
Molecular Biology、Immunology、RNA Biology
招聘详情
A postdoctoral research fellow position is available at the Mayo Medical School – Mayo Clinic (Rochester, Minnesota) to study the functions and mechanisms of post-transcriptional regulations in innate immune responses.
Mayo Clinic is widely regarded as one of the United States' greatest hospitals and ranked No. 1 in the country on the 2016–2017 U.S. News & World Report List of "Best Hospitals" of the United States, maintaining a position near the top for more than 25 years.
The potential candidate will utilize primary cell culture systems and mouse models in combination with high throughput RNA sequencing, ribosome-profiling, CLIP-seq to study how mRNA binding proteins and long noncoding RNAs control gene expression under normal and pathological conditions.
Highly motivated individuals with a recent Ph.D. and a background in immunology are encouraged to apply. Evidence of scientific publications is required and previous experience with either of the following are desirable: 1) mouse embryonic stem cells; 2) immunology; 3) RNA biology; 4) Bioinformatics.
The salary is in accordance with the NIH standard. The start time is flexible in 2017.
Please send a CV including the contact information for at least two references to Dr. Wenqian Hu.
Selective Publications
Zhang, X., Chen, X., Liu, Q., Zhang, S., and Hu, W. * (2017) Translation repression via modulation of the cytoplasmic poly(A) binding protein in the inflammatory response. eLife 6: e27786. doi: 10.7554/eLife.27786 (*correspondence author)
Alvarez-Dominguez, J.R., Zhang, X., and Hu, W.* (2017) Widespread and dynamic translational control of red blood cell development. Blood 129:619-629 (*correspondence author)
Hu, W. *, Yuan, B., and Lodish, H.F. (2014) Cpeb4-mediated translational regulatory circuitry controls erythroid terminal differentiation. Developmental Cell 30(6):660-672 (*correspondence author)
Alvarez-Dominguez, J.R., Hu, W.*, Yuan, B., Shi, J., Park, S.S., Gromatzky, A.A., van Oudenaarden, A. and Lodish, H.F.* (2014) Multiple types of long non-coding RNAs regulate red blood cell development. Blood123:570-581 (* correspondence authors)
Hu, W., Yuan, B., Flygare, J. and Lodish, H.F. (2011) Long non-coding RNA mediated anti-apoptotic activity in murine erythroid terminal differentiation. Genes & Development 25:2559-2572
Hu, W., Petzold, C., Baker, K., and Coller, J. (2010) Nonsense-mediated mRNA decapping occurs on polyribosomes in Saccharomyces cerevisiae. Nature Structural & Molecular Biology 17:244-247
Hu, W., Sweet, T., Chamnongpol, S., Baker, K., and Coller, J. (2009) Co-translational mRNA decay inSaccharomyces cerevisiae. Nature 461:225-229
申请材料
CVContact information of at least two references
待遇福利
The salary is in accordance with the NIH standard.
申请方式
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