Education
2012.9-2017.6: Bachelor of Clinical Medicine, Clinical Medicine, University of South China
2017.9-2020.6: Master of Obstetrics and Gynecology, Clinical Medicine, Central South University
2020.9-Present：PhD candidate in Neurosurgery ,Clinical Medicine, Central South University
Research Interests
Cancer Cell Biology
Research Projects
1. Central South University Graduate Student Independent Innovation Project,Principal Investigator (2018–2020)
2. National Key R&D Program "Reproductive Health and Women and Children's Health Protection” (2021YFC270202）,Participant (2021–2024)
Publications
1. Huang C, Zhao W, Hao Q, Chen J, Wu L, Yang W, Lu H, Zhang Y#, Zhou X#. CKAP4 and mutant p53 cooperatively abrogate cell cycle checkpoint to induce genotoxic resistance in ovarian cancer. Clin Transl Med.2023.
2. Huang C, Hao Q, Shi G, Zhou X, Zhang Y.BCL7C suppresses ovarian cancer growth by inactivating mutant p53. J Mol Cell Biol. 2021
3.Chen Y, Hao Q, Wang J, Li J, Huang C, Zhang Y, Wu X, Lu H, Zhou X. Ubiquitin ligase TRIM71 suppresses ovarian tumorigenesis by degrading mutant p53. Cell Death Dis. 2019.
4. Wang J, Chen Y, Huang C, Hao Q, Zeng SX, Omari S, Zhang Y, Zhou X, Lu H. Valosin-Containing Protein Stabilizes Mutant p53 to Promote Pancreatic Cancer Growth. Cancer Res. 2021.
5. Liu H, Fu H, Yu C, Zhang N#, Huang C, Lv L, Hu C, Chen F, Xiao Z, Zhang Z, Lu H, Yuan K#. Transcriptional pausing induced by ionizing radiation enables the acquisition of radio-resistance in nasopharyngeal carcinoma. J Mol Cell Biol. 2023.
6.Ni H, Huang C, Ran Z, Li S, Kuang C#, Zhang Y#, Yuan K.# Targeting HPV for the Prevention, Diagnosis, and Treatment of Cervical Cancer. J Mol Cell Biol. 2024.
7.Li S, Zhang J, Ran Z, Huang C, Wang X, Li Y, Liu J, Kuang C, Yuan K# Research Progress of Endogenous Retroviruses in Tumors and Other Human Diseases. 《Chinese Science Life Sciences》. 2024
Patents
1. Yuan Kai, Liu Honglu, Yu Chunhong, Zhang Na, Meng Yang, Huang Canhua, Chen Fang. Application of CDK7 Inhibitor THZ1 in Radiotherapy Resistance Treatment of Nasopharyngeal Carcinoma. 2022, China, Patent Application No.: 202210090425.0
Email：208102122@csu.edu.com