working experience:
2020.12 until now, School of Chemistry and Chemical Engineering, Beijing Institute of Technology, Specia
Researcher/Pre-appointed Associate, Professor, PhD Supervisor
2017.8-2020.6, School of Chemistry, Rice University, USA, Postdoctoral researcher (Co-supervisor: Prof. Han Xiao)
Educational experience:
2012.9-2017.7, School of Chemistry, Peking University, PhD, Supervisor: Prof. Zhang Junlong
2008.9-2012.7, School of Pharmacy, Wuhan University, B.D, Supervisor: Prof. Zhou Haibing
Research interests:
mainly focus on the intersections of chemistry and life science, committed to developing chemical tools to detect and regulate life processes, reveal the rules of occurrence and development of biological events, provide new ideas for the treatment of diseases.
Specifically:
1. Develop anionic ligands to achieve controlled release of phosphate-containing drugs .
2. Develop anionic ligands to disrupt the homeostasis of phosphate-containing species in tumor cells to treat tumors.
3. Develop light-activated fluorescent probes to detect the dynamics of cell communication
Email: tangjuan@bit.edu.cn
Office: Industrial Ecological Building 419
Representative papers:
1. Juan Tang, # Michael Robichaux, # Kuan-Lin Wu, Jingqi Pei, Nhung T. Nguyen, Yubin Zhou, Theodore G. Wensel*, and Han Xiao*, Single-Atom Fluorescence Switch: A General Approach towards Visible Light-Activated Dyes for Biological Imaging, J. Am. Chem. Soc., 2019, 141, 37, 14699 (# contributed equally). Highlighted by JACS Spotlight [Link], and C&EN [Link]. Featured in Rice News [Link], and ScienceDaily [Link]
2. Juan Tang, # Lushun Wang, # Axel Loredo, Carson Cole, and Han Xiao*, Single-Atom Replacement as a General Approach Towards Visible-Light/Near-Infrared Heavy-Atom-Free Photosensitizers for Photodynamic Therapy, Chem. Sci., 2020, 11, 6701 (# contributed equally). Included in 2020 Chemical Science HOT Article Collection [Link], Featured in Rice News [Link] Phys.org [Link]
3. Juan Tang, # Chenfei Yu, Axel Loredo, Yuda Chen, and Han Xiao*, Site-Specific Incorporation of a Photoactivatable Fluorescent Amino Acid, ChemBioChem, 2021, 22, 501 (# contributed equally)
4. Juan Tang, Hao-Yan Yin, Jun-Long Zhang*, A luminescent aluminium salen complex allows for monitoring dynamic vesicle trafficking from the Golgi apparatus to lysosomes in living cells, Chem. Sci., 2018, 9, 1931
5. Juan Tang, Yuan-Bo Cai, Jing Jing and Jun-Long Zhang*, Unravelling the Correlation between Metal Induced Aggregation and Cellular Uptake/Subcellular Localization of Znsalen: An Overlooked Rule for Design of Luminescent Metal Probes, Chem. Sci., 2015, 6, 2389