Name: Ping Li 姓名：李平
Occupation: Professor / Doctoral supervisor职业：教授/博士生导师
Current Affiliation: College of Chemistry, Shandong Normal University, 88 East Wenhua Road, Jinan, 250014, P.R. China现任职单位：中国山东省济南市文化东路 88 号 山东师范大学化学学院，邮编：250014
Phone: 86-531-86182897 电话：86-531-86182897
E-mail: lip@sdnu.edu.cn 电子邮件：lip@sdnu.edu.cn
EDUCATION BACKGROUND 教育背景
1. Sep. 1991 – Jul.1995, Shandong Normal University, B. S., Chemistry1991 年 9 月 - 1995 年 7 月，山东师范大学，理学学士，化学专业
2. Sep. 1995 – Jul.1998, Xi’an Modern Chemistry Research Institute, Master, Organic Chemistry1995 年 9 月 - 1998 年 7 月，西安近代化学研究所，硕士，有机化学
3. Sep. 2002 – Jul. 2008, Shandong Normal University, Ph. D., Botany, Cell Analysis2002 年 9 月 - 2008 年 7 月，山东师范大学，植物学专业，细胞分析方向，博士。
WORKING EXPERIENCE 工作经验
1. Jul. 1998 – Nov. 2000, Shandong Normal University, teaching assistant1998 年 7 月 - 2000 年 11 月，山东师范大学，助教
2. Dec. 2000 – Nov. 2006, Shandong Normal University, lecturer2000 年 12 月 - 2006 年 11 月，山东师范大学，讲师
3. Dec. 2006 – Nov. 2012, Shandong Normal University, associate professor2006 年 12 月 - 2012 年 11 月，山东师范大学，副教授
4. Feb. 2010 – Sep. 2010, Ohio University, visiting scholar2010 年 2 月 - 2010 年 9 月，俄亥俄大学，访问学者
5. May. 2012 – present, Shandong Normal University, professor2012 年 5 月至今，山东师范大学，教授
PROFESSIONAL TITLES 专业职称
1. 2020 Electee of Special Government Allowances from the State Council2020 年国务院特殊津贴获得者
2. 2019 Electee of National Millions of Talents Projects2019 年国家“万人计划”入选者
3. 2019 National Middle-aged and Young Experts with Outstanding Contributions2019 年全国杰出中青年专家
4. 2017 Taishan Scholar Distinguished Professor2017 年泰山学者特聘教授
5. 2016 Leader of the Innovation Team of "Yangtze River Scholars and Innovation Team Development Plan" of the Ministry of Education2016 年教育部“长江学者和创新团队发展计划”创新团队负责人
6. 2018 Key Member of "Huang Danian-Style Teacher’s Team of National University" of the Ministry of Education2018 年教育部“黄大年式教师团队”骨干成员
7. 2015 Young and Middle-aged Experts with Outstanding Contributions of Shandong Province2015 年山东省有突出贡献的中青年专家
8. 2013 Chief Expert of Key Laboratory of Universities of Shandong Province8. 2013 年山东省高校重点实验室首席专家
9. 2020 Professional Committee Member of Shandong Biomedical Engineering Society2020 年山东省生物医学工程学会专业委员会委员
10. 2020 Editorial Board Member of AIMS Materials Science2020 年 AIMS 材料科学编辑委员会成员
11. 2015 Decision Consultant Expert of National Science and Technology Think Tank of Shandong Association for Science and Technology2015 年山东省科学技术协会科技智库决策咨询专家
12. 2022 Senior Member of Chinese Chemical Society2022 年 中国化学会高级会员
13. 2022 Member of Academic Committee of Shandong Normal University13. 2022 年 山东师范大学学术委员会委员
14. 2022 Seventh Committee Member of Zhigong Party of Shandong Province14. 2022 年山东省致公党第七届委员会委员
15. 2022 Chairman of Grass-roots Committee of Zhigong Party of Shandong Normal University15. 2022 年 山东师范大学致公党基层委员会主任委员
AWARDS AND HONORS 奖项及荣誉
1. 2018 The Second Prize of National Natural Science Award of China (3/5)2018 年国家自然科学奖二等奖（第五完成人）
2. 2007 The Second Prize of National Science and Technology Progress Award of China (8/10)2007 年国家科学技术进步奖二等奖（第 8 完成人/共 10 人）
3. 2015 The First Prize of Natural Science Award of Shandong Province (2/4)2015 年山东省自然科学奖一等奖（2/4）
4. 2019 The Second Prize of Natural Science Award of Shandong Province (1/4)2019 年山东省自然科学奖二等奖（第 1 完成人/共 4 人）
5. 2004 The First Prize of Science and Technology Progress Award of Shandong Province (5/8)
6. 2015 The Youth Science and Technology Award of Shandong Province
7. 2014 The Second Prize of Outstanding Scientific Research Achievements of Shandong universities (1/3)
8. 2022 The First Prize of Teaching Achievement Award of Shandong Province (7/10)
9. 2018 The First Prize of Teaching Achievement Award of Shandong Province (9/10)
10. 2018 The First Prize of Postgraduate Education and Teaching Achievement Award of Shandong Normal University (9/10)
11. 2006 Patent Award of Jinan (3/4)
12. 2021 The Most Beautiful Teacher in Qilu—Shandong Teaching and Educating Model
13. 2021 Education System Female Staff Achievement Model of Shandong Province
14. 2021 Excellent Postgraduate Guidance Team Director of Shandong Province
RESEARCH INTERESTS
Professor Ping Li's current research interests focus on the optical imaging analysis of disease-related biomarkers, the exploration of molecular mechanisms for major diseases such as depression, cancer, etc. and the construction of theranostic reagents. Main innovative achievements include: (1) Developing new imaging materials and methods to capture disease-related biomarkers for the study of molecular mechanisms and early diagnosis and treatment of major diseases such as depression, cancer, etc.; (2) Based on the reversible and specific recognition reactions, achieving the real-time, in situ and highly sensitive analyzation of the dynamic flux of bioactive molecules in living cells and sub-organelles; (3) Based on two-photon, near-infrared and other functional optical imaging agents, realizing the in situ visualized analysis of bioactive molecules in vivo.
Professor Ping Li has presided and completed 1 project of the National Key Basic Research and Development Program (“973 Plan”), 3 projects of the National Natural Science Foundation of China, 1 sub-project of the National Major New Drug Creation Project, 1 project of the National Natural Science Foundation of China Youth Fund, 1 major basic research project of Shandong Province the Natural Science Foundation and 1 key scientific and technological project of Shandong Province. She is now presiding 1 project of the National Natural Science Foundation of China. Up to now, Professor Ping Li has published more than 80 papers in well-known international chemical academic journals such as Chem. Soc. Rev., J. Am. Chem. Soc., Angew. Chem. Int. Ed., Chem. Sci., Anal. Chem., Chem. Commun., with a total citation in excess of 3,000 times.
RESEARCH PROJECTS
1. Jan. 2021 – Dec. 2024 National Natural Science Foundation of China (No. 22074083), 630,000, Host, At study
2. Jan. 2017 - Dec. 2020 Sub-Project of National Major New Drug Creation Project (No. 2017ZX09301030004), 1,241,700, Host, Finished
3. Jan. 2017 - Dec. 2020 National Natural Science Foundation of China (No. 21675105), 650,000, Host, Finished
4. Jan. 2013 – Aug. 2017 Subject of National Key Basic Research and Development Program (“973 Plan”) (No. 2013CB933804), 1400,000, Host, Finished
5. Jan. 2015 - Dec. 2018 National Natural Science Foundation of China (No. 21475079), 900,000, Host, Finished
6. Jan. 2010 - Dec. 2012 National Natural Science Foundation of China (No. 20975063), 360,000, Host, Finished
7. Jan. 2013. - Dec. 2015 National Natural Science Foundation of China Youth Fund (No. 21205073), 270,000, Host, Finished
8. Aug. 2017 – Jul. 2019 Major Basic Research Project of Natural Science Foundation of Shandong Province (No. ZR2017ZC0225), 1,200,000, Host, Finished
9. Jan. 2010 - Dec. 2013 Key Scientific and Technological Project of Shandong Province (No. 2010G0020243), 360,000, Host, Finished
SELECTED PUBLICATIONS
(1)Hui Wang,* Hongtong Wang, Tiancong Xiu, Xiaoting Zhang, Yue Tang,* Wei Zhang, Wen Zhang, Ping Li* and Bo Tang.* A “Cocktail” Fluorescent Probe for Multi-ROS Imaging Unveils Ferroptosis-Driven Liver Fibrosis Development. Angew. Chem. Int. Ed., 2025, 65, 35, e202506728.
(2) Qi Ding, Deqiang Li, Xin Zhang, Xue Xue, Ran Zhang, Di Su, Tony D. James, Ping Li,* Xin Wang* and Bo Tang.* Restoring the Redox and Norepinephrine Homeostasis in Mouse Brains Promotes an Antidepressant Response. J. Am. Chem. Soc., 2025, 147, 13, 11239–11249.
(3) Wen Zhang, Jihong Liu, Ping Li,* Xin Wang* and Bo Tang.* Reversible Fluorescent Probes for Dynamic Imaging of Liver Ischemia-Reperfusion Injury. Acc. Chem. Res., 2024, 57, 17, 2594–2605.
(4) Xin Wang, Qi Ding, Robin R. Groleau, Luling Wu, Yuantao Mao, Feida Che, Oxana Kotova , Eoin M. Scanlan, Simon E. Lewis,* Ping Li,* Bo Tang,* Tony D. James,* and Thorfinnur Gunnlaugsson.* Fluorescent Probes for Disease Diagnosis. Chem. Rev., 2024, 124, 11, 7106-7164.
(5) Hui Wang,† Xiaoting Zhang,† Ping Li,* Fang Huang, Tiancong Xiu, Hongtong Wang, Wei Zhang, Wen Zhang and Bo Tang.* Prediction of Early Atherosclerotic Plaques using a Sequence-Activated Fluorescence Probe for the Simultaneous Detection of γ-Glutamyl Transpeptidase and Hypobromous Acid. Angew. Chem. Int. Ed., 2023, e202315861.
(6) Di Su, Ran Zhang, Xin Wang,* Qi Ding, Feida Che, Zhenzhen Liu, Jingwen Xu, Yuying Zhao, Kunqian Ji, Wei Wu,* Chuanzhu Yan,* Ping Li,* and Bo Tang.* Shedding Light on Lysosomal Malondialdehyde Affecting Vitamin B12 Transport during Cerebral Ischemia/Reperfusion Injury. J. Am. Chem. Soc., 2023, 145, 22609-22619.
(7) Jihong Liu, Wen Zhang,* Xin Wang, Qi Ding, Chuanchen Wu, Wei Zhang, Luling Wu,* Tony D. James,* Ping Li,* and Bo Tang.* Unveiling the Crucial Roles of O2•– and ATP in Hepatic Ischemia–Reperfusion Injury Using Dual-Color/Reversible Fluorescence Imaging. J. Am. Chem. Soc., 2023, 145, 36, 19662-19675.
(8) Jihong Liu, Wen Zhang,* Chunmiao Zhou, Mengmei Li, Xin Wang, Wei Zhang, Zhenzhen Liu, Luling Wu,* Tony D. James,* Ping Li,* and Bo Tang.* Precision navigation of hepatic ischemia reperfusion injury guided by lysosomal viscosity-activatable NIR-Ⅱ fluorescence. J. Am. Chem. Soc., 2022, 144, 30, 13586–13599.
(9) Luling Wu,† Jihong Liu,† Xue Tian,† Robin R. Groleau, Beidou Feng, Yonggang Yang, Adam C. Sedgwick, Hai-Hao Han,* Yang Wang, Han-Min Wang, Fang Huang, Steven D. Bull, Hua Zhang,* Chusen Huang,* Yi Zang, Jia Li, Xiao-Peng He, Ping Li,* Bo Tang, Tony D. James,* and Jonathan L. Sessler*. Dual-Channel Fluorescent Probe for the Simultaneous Monitoring of Peroxynitrite and Adenosine-5′-triphosphate in Cellular Applications. J. Am. Chem. Soc., 2022, 144, 174-183.
(10) Luling Wu,†,* Jihong Liu,† Ping Li,* Bo Tang* and Tony D. James*, Two-photon small-molecule fluorescence-based agents for sensing, imaging, and therapy within biological systems. Chem. Soc. Rev., 2021, 50, 702-734.
(11) Qi Ding,† Ying Tian,† Xin Wang,* Ping Li,* Di Su, Chuanchen Wu, Wen Zhang, and Bo Tang*. Oxidative Damage of Tryptophan Hydroxylase‑2 Mediated by Peroxisomal Superoxide Anion Radical in Brains of Mouse with Depression. J. Am. Chem. Soc., 2020, 142, 20735–20743.
(12) Haibin Xiao,† Wen Zhang,† Ping Li,* Wei Zhang, Xin Wang, and Bo Tang*. Versatile fluorescent probes for visualizing superoxide anion in living cells and in vivo. Angew. Chem. Int. Ed., 2020, 132, 4244-4258.
(13) Xin Wang; Ping Li,* Qi Ding; Chuanchen Wu; Wen Zhang; Bo Tang*. Observation of Acetylcholinesterase in Stress-induced Depression Phenotypes by Two-photon Fluorescence Imaging in the Mouse Brain. J. Am. Chem. Soc., 2019, 141(5): 2061~2068.
(14) Xin Wang, Ping Li,* Qi Ding, Chuanchen Wu, Wen Zhang, and Bo Tang*. Illuminating the Function of the Hydroxyl Radical in the Brains of Mice with Depression Phenotypes by Two‐Photon Fluorescence Imaging. Angew. Chem. Int. Ed., 2019, 58, 4674-4678.
(15) Wei Zhang, Jun Lu, Xiaonan Gao, Ping Li,* Wen Zhang, Yu Ma, Hui Wang, Bo Tang*. Enhanced Photodynamic Therapy by Reduced Levels of Intracellular Glutathione Obtained By Employing a Nano-MOF with CuII as Active Center. Angew. Chem. Int. Ed., 2018, 57, 4891-4896.
(16) Ping Li, Lu Liu, Haibin Xiao, Wei Zhang, Lulin Wang, and Bo Tang*. A New Polymer Nanoprobe Based on Chemiluminescence Resonance Energy Transfer (CRET) for Ultrasensitive Imaging of Intrinsic Superoxide Anion in Mice. J. Am. Chem. Soc., 2016, 138, 2893-2896.
(17) Wei Zhang, Wei Liu, Ping Li,* Haibin Xiao, Hui Wang, and Bo Tang*. A Fluorescence Nanosensor for Glycoproteins with Activity Based on the Molecularly Imprinted Spatial Structureof the Target and Boronate Affinity. Angew. Chem. Int. Ed., 2014, 53, 12489-12493.
(18) Wen Zhang,† Ping Li,† Fan Yang, Xiufen Hu, Chuanzhi Sun, Wei Zhang, Dezhan Chen, and Bo Tang*. Dynamic and Reversible Fluorescence Imaging of Superoxide Anion Fluctuations in Live Cells and in Vivo. J. Am. Chem. Soc., 2013, 135, 14956-14959.