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Hou Sihua Group, Shanghai Jiao Tong University
Synthesis and functional study of bioactive natural products
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Sihua Hou
Tenure-track Associate Professor, Ph.D. advisor, Principal Investigator (PI)
Synthesis and functional study of bioactive natural products
Dr Sihua Hou received his B.S. (2010) and Ph.D. (2015) in Organic Chemistry from Lanzhou University . Following postdoctoral studies at Shanghai Jiao Tong University and The University of Chicago, he began his independent career at School of Pharmaceutical Sciences, Shanghai Jiao Tong University as a Tenure-track Associate Professor, Ph.D. Advisor and Principal Investigator(PI) in 2021. Currently, Our research is studying the synthesis and function of biologically active natural products. Our research will focus on the key scientific questions about the scarcity of natural products’ natural supplies and novel mechanisms of action of the natural products, to develop urgently needed pharmaceuticals based on natural products for the clinical treatments of severe diseases. Natural product synthesis, medicinal chemistry, and chemical biology research areas will be integrated.
Research
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1、Total synthesis of bioactive natural products 2、Target molecule-oriented novel and efficient synthesis methodology research 3、Development of novel anti-tumor, anti-inflammatory and immunomodulatory drug candidates
News
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November 2025: Our total synthesis work @SJTU has been published in JACS. Congratulations to Xingqian, Xiang, Pengfei, Baokuan and team!
课题组参加研究生导学团队素质拓展活动
September 2025: Welcome our new postdoctoral scholar, Baokuan! Welcome our new graduate students Hao Yang, Wenxu, Bohan!
Sept 2025:Welcome Prof. Ryan Shenvi's Visit and Thanks for the Great Talk!
祝贺朱蓉,张博宏,柯天,毕业快乐!
May 2025:Welcome Prof. Han-Feng Ding's Visit and Thanks for the Great Talk!
March 2025: Our divergent total syntheses of Crinipellins @SJTU has been published in Angew Chem. Congratulations to Tian Ke, Yun-Peng Wang, Kun Fang, Jing-Han Hu, Ka Lu and team!
September 2024: Our another total synthesis work @SJTU has been published in JACS. Congratulations to Xue Yuan, Zhang Xiang and team!
August 2024:Welcome Prof. Guangbin Dong's Visit and Thanks for the Great Talk!
July 2024: Welcome our new postdoctoral scholar, Pengfei Lian!
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September 2024! Congratulations to Xue Yuan, Zhang Xiang!
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