一、个人简介

武汉纺织大学生物工程与健康学院教师，骨干人才。武汉大学获得化学生物学博士学位（导师：周翔院士，2012-2017）。博士毕业后，先后在加拿大阿尔伯塔大学（合作导师：X. Chris Le院士，2017–2020）及美国芝加哥大学（合作导师：Jingyi Fei教授， 2020–2024）从事博士后研究。以第一作者或共同第一作者在Science Advances、Angewandte Chemie International Edition、Chemical Science、Chemical Communications等国际权威期刊发表论文4篇，授权国家发明专利1项。

二、研究领域

1. 基于核酸的分子诊断平台开发；

2. CRISPR系统的优化与应用研究；

3. 纳米药物载体及靶向药物递送；

三、代表性论文

1. Jinjun Wu^#, Yu Xiao^#, Yunzheng Liu^#, Li Wen, Chuanyang Jin, Shun Liu, Sneha Paul, Chuan He, Oded Regev*, Jingyi Fei*. Dynamics of RNA localization to nuclear speckles are connected to splicing efficiency. Sci. Adv. 2024, 10, eadp7727.

2. Jinjun Wu^#, Hanyong Peng^#, Xiufen Lu, Maode Lai, Hongquan Zhang^*, X. Chris Le^*. Binding-Mediated Formation of Ribonucleoprotein Corona for Efficient Delivery and Control of CRISPR/Cas9. Angew. Chem., Int. Ed. 2021, 133, 11204–11209.

3. Jinjun Wu^#, Heng Xiao^#, Tianlu Wang^#, Tingting Hong, Boshi Fu, Dongsheng Bai, Zhiyong He, Shuang Peng, Xiwen Xing, Jianlin Hu, Pu Guo, Xiang Zhou^*. N⁶-hydroperoxymethyladenosine: a new intermediate of chemical oxidation of N⁶-methyladenosine mediated by bicarbonate-activated hydrogen peroxide. Chem. Sci. 2015, 6, 1240–1243.

       4. Chen Xu^#, Jinjun Wu^#, Wenting Liu, Tingting Hong, Tianlu, Wang, Xiaoe Zhang, Boshi Fu, Fan Wu, Zhiguo, Wu^*, Xiang Zhou^*. Detecting 5-methylcytosine using an enzyme-free DNA strand exchange reaction without pretreatment under physiological conditions. Chem. Commun. 2016, 52, 6833−6836.