刘开政，博士，中国科学院深圳先进技术研究院副研究员。欧盟玛丽居里学者，比利时鲁汶大学博士后，欧洲分子生物学会（EMBO）短期基金获得者。分别在南开大学、英国伦敦大学学院和荷兰奈梅亨大学取得学士、硕士和博士学位。与欧洲科研机构合作，致力于3D微环境中的细胞生物力学研究以及新型非线性人工聚合物材料-螺旋聚异腈（PIC）水凝胶的研发、生产与生物医学应用。在Nature Protocols、The Proceedings of the National Academy of Sciences（PNAS）、Cell Reports Physical Science、Bioactive Materials、ACS Applied Materials & Interfaces和Biomacromolecules等国际高水平杂志发表论文十余篇。
学术任职：Smart Materials in Medicine、Frontiers in Bioengineering、ACS Pharmacology & Translational Science与ACS Applied Materials & Interfaces期刊独立审稿人。
主要代表论著:
1. Yuan, H.#*, Liu, K.#*, van Velthoven, M. J., Kumari, J., Bao, Y., Rocha, S., & Kouwer, P. H.* (2025). Fibrous polyisocyanide hydrogels for 3D cell culture applications. Nature Protocols, 1-22. （共同第一作者&共同通讯作者）
1. Liu, K.#, Fang, X.#, Aazmi, A.#, Wang, Q.#, Gong, X.#, Chen, Z.#, ... & Ruan, C. (2024). Organoids: Principle, application and perspective. The Innovation Life, 2(3), 100088-1. （第一作者）
2. Liu, K.#, Vandaele, J.#, Yuan, H., Blank, K. G., Hammink, R., Kouwer, P. H., & Rocha, S. (2024). Structure and applications of PIC-based polymers and hydrogels. Cell Reports Physical Science, 5(2), 101834. （第一作者）
3. Yuan, H.#, Liu, K.#, Cóndor, M., Barrasa-Fano, J., Louis, B., Vandaele, J., ... & Rocha, S. (2023). Synthetic fibrous hydrogels as a platform to decipher cell–matrix mechanical interactions. Proceedings of the National Academy of Sciences, 120(15), e2216934120. （共同第一作者）
4. Liu, K., Wiendels, M., Yuan, H., Ruan, C., & Kouwer, P. H. (2022). Cell-matrix reciprocity in 3D culture models with nonlinear elasticity. Bioactive materials, 9, 316-331. （第一作者，ESI高被引论文）
5. Liu, K., Veenendaal, T., Wiendels, M., Ruiz-Zapata, A. M., van Laar, J., Kyranas, R., Enting, H., van Cranenbroek, B., Koenen, H., Mihaila, S., Oosterwijk, E., Kouwer, P.H. (2020) Synthetic extracellular matrices as a toolbox to tune stem cell secretome. ACS applied materials & interfaces,12(51), 56723-56730. （第一作者）
6. Liu, K., Mihaila, S. M., Rowan, A., Oosterwijk, E., & Kouwer, P. H. (2019). Synthetic extracellular matrices with nonlinear elasticity regulate cellular organization. Biomacromolecules, 20(2), 826-834. （第一作者）
7. Ma, C.#, Liu, K.#, Li, Q., Xiong, Y., Xu, C., Zhang, W., Ruan C., Li X., & Lei, X. (2022). Synthetic Extracellular Matrices for 3D Culture of Schwann Cells, Hepatocytes, and HUVECs. Bioengineering, 9(9), 453. （共同第一作者）
8. Liu, K., Vandaele, J., Bernhagen, D., van Erp, M., Oosterwijk, E., Timmerman, P., ... & Kouwer, P. H. (2022). Rapid stem cell spreading induced by high affinity α5β1 integrin-selective bicyclic RGD peptide in biomimetic hydrogels. bioRxiv, 2022-02.