英文书：《Cancer Cell Metabolism: A Potential Target for Cancer Therapy》
编辑 Editors：Dhruv Kumar
Reveals the molecular mechanism of metabolic regulation in cancer cells
Provides comprehensive, up-to-date information on different types of metabolic alteration in cancer cells with comparison to normal cells
Offers an authoritative account of the latest findings on all clinically approved and prospective anti-cancer drugs targeting the metabolic process and associated signalling pathways in the cancer cells
This book illustrates various aspects of cancer cell metabolism, including metabolic regulation in solid tumours vs. non-solid tumours, the molecular pathways involved in its metabolism, and the role of the tumour microenvironment in the regulation of cancer cell metabolism. It summarizes the complexity of cancer cell metabolism in terms of the switch from anaerobic to aerobic glycolysis and how mitochondrial damage promotes aerobic glycolysis in cancer cells. The respective chapters provide the latest information on the metabolic remodelling of cancer cells and elucidate the important role of the signalling pathways in reprogramming of cancer cell metabolism. In addition, the book highlights the role of autophagy in cancer cell metabolism, and how metabolic crosstalk between cancer cells and cancer-associated fibroblasts promotes cancer cell progression. In closing, it summarizes recent advancements in drug development through targeting cancer metabolism.
Cancer cell metabolism Metabolic alteration Targeting metabolic alteration anti-cancer drug therapy Diagnostic markers
Cancer Cell Metabolism: Solid Tumor Versus Nonsolid Tumor
Sibi Raj, Vaishali Chandel, Dhruv Kumar
Reprogramming of Cancer Cell Metabolism: Warburg and Reverse Warburg Hypothesis
Samyukta Narayanan, Anirudh Santhoshkumar, Srijit Ray, Sitaram Harihar
Molecular Aspects of Cancer Cell Metabolism: Altered Glycolysis and Lipid Metabolism
Sandesh Kumar Patel, Deepanshu Verma, Neha Garg
Understanding the Metabolic Cross Talk Between Cancer Cells and Cancer-Associated Fibroblasts
Anthony Michael Alvarado, Levi Kent Arnold, Sufi Mary Thomas
Metabolic Cross Talk Between Cancer Cells and Tumor Microenvironment
Satish S. Poojary, Maryam Ghufran, Ananya Choudhary, Mehreen Aftab
Role of Autophagy in Cancer Cell Metabolism
Diego A. Pedroza, Vaishali Chandel, Dhruv Kumar, Prakash Doddapattar, M. S. Biradar, Rajkumar Lakshmanaswamy et al.
Role of c-Met/HGF Axis in Altered Cancer Metabolism
Vaishali Chandel, Sibi Raj, Ramesh Choudhari, Dhruv Kumar
Recent Advances in Drug Development Targeting Cancer Metabolism
Narayan Sugandha, Lovika Mittal, Amit Awasthi, Shailendra Asthana
Clinical Relevance of “Biomarkers” in Cancer Metabolism
Niraj Kumar Jha, Saurabh Kumar Jha, Ankur Sharma, Rahul Yadav, Pratibha Pandey, Kavindra Kumar Kesari et al.
Alterations in Metabolite-Driven Gene Regulation in Cancer Metabolism
Saurabh Kumar Jha, Rahul Yadav, Kumari Swati, Niraj Kumar Jha, Ankur Sharma, Fahad Khan et al.
Role of Phytochemicals in Cancer Cell Metabolism Regulation
Abhijeet Kumar, Anil Kumar Singh, Mukul Kumar Gautam, Garima Tripathi
Correction to: Cancer Cell Metabolism: A Potential Target for Cancer Therapy