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书籍《Cancer Cell Metabolism: A Potential Target for Cancer Therapy》
发布时间:2021-08-17

英文书:《Cancer Cell Metabolism: A Potential Target for Cancer Therapy》

中译名:《癌细胞代谢:癌症治疗的潜在靶点》

编辑 Editors:Dhruv Kumar

Reveals the molecular mechanism of metabolic regulation in cancer cells

Provides comprehensive, up-to-date information on different types of metabolic alteration in cancer cells with comparison to normal cells

Offers an authoritative account of the latest findings on all clinically approved and prospective anti-cancer drugs targeting the metabolic process and associated signalling pathways in the cancer cells


书籍简介Book Introduction:

This book illustrates various aspects of cancer cell metabolism, including metabolic regulation in solid tumours vs. non-solid tumours, the molecular pathways involved in its metabolism, and the role of the tumour microenvironment in the regulation of cancer cell metabolism. It summarizes the complexity of cancer cell metabolism in terms of the switch from anaerobic to aerobic glycolysis and how mitochondrial damage promotes aerobic glycolysis in cancer cells. The respective chapters provide the latest information on the metabolic remodelling of cancer cells and elucidate the important role of the signalling pathways in reprogramming of cancer cell metabolism. In addition, the book highlights the role of autophagy in cancer cell metabolism, and how metabolic crosstalk between cancer cells and cancer-associated fibroblasts promotes cancer cell progression. In closing, it summarizes recent advancements in drug development through targeting cancer metabolism.


封面:


关键词 Keywords:

Cancer cell metabolism Metabolic alteration Targeting metabolic alteration anti-cancer drug therapy Diagnostic markers

目录:

Cancer Cell Metabolism: Solid Tumor Versus Nonsolid Tumor

Sibi Raj, Vaishali Chandel, Dhruv Kumar

Pages 1-13

Reprogramming of Cancer Cell Metabolism: Warburg and Reverse Warburg Hypothesis

Samyukta Narayanan, Anirudh Santhoshkumar, Srijit Ray, Sitaram Harihar

Pages 15-26

Molecular Aspects of Cancer Cell Metabolism: Altered Glycolysis and Lipid Metabolism

Sandesh Kumar Patel, Deepanshu Verma, Neha Garg

Pages 27-37

Understanding the Metabolic Cross Talk Between Cancer Cells and Cancer-Associated Fibroblasts

Anthony Michael Alvarado, Levi Kent Arnold, Sufi Mary Thomas

Pages 39-53

Metabolic Cross Talk Between Cancer Cells and Tumor Microenvironment

Satish S. Poojary, Maryam Ghufran, Ananya Choudhary, Mehreen Aftab

Pages 55-63

Role of Autophagy in Cancer Cell Metabolism

Diego A. Pedroza, Vaishali Chandel, Dhruv Kumar, Prakash Doddapattar, M. S. Biradar, Rajkumar Lakshmanaswamy et al.

Pages 65-87

Role of c-Met/HGF Axis in Altered Cancer Metabolism

Vaishali Chandel, Sibi Raj, Ramesh Choudhari, Dhruv Kumar

Pages 89-102

Recent Advances in Drug Development Targeting Cancer Metabolism

Narayan Sugandha, Lovika Mittal, Amit Awasthi, Shailendra Asthana

Pages 103-126

Clinical Relevance of “Biomarkers” in Cancer Metabolism

Niraj Kumar Jha, Saurabh Kumar Jha, Ankur Sharma, Rahul Yadav, Pratibha Pandey, Kavindra Kumar Kesari et al.

Pages 127-146

Alterations in Metabolite-Driven Gene Regulation in Cancer Metabolism

Saurabh Kumar Jha, Rahul Yadav, Kumari Swati, Niraj Kumar Jha, Ankur Sharma, Fahad Khan et al.

Pages 147-165

Role of Phytochemicals in Cancer Cell Metabolism Regulation

Abhijeet Kumar, Anil Kumar Singh, Mukul Kumar Gautam, Garima Tripathi

Pages 167-184

Correction to: Cancer Cell Metabolism: A Potential Target for Cancer Therapy

Dhruv Kumar

Pages C1-C1


链接:https://link.springer.com/book/10.1007/978-981-15-1991-8