（1） 主持国家自然科学基金青年项目，22204126，基于微流控DNA组合连接编码的单细胞蛋白-蛋白邻近测序分析，2023/01-2025/12，30万；

（2）主持中国博士后科学基金面上项目（一等），2021M690124，微流分选细胞亚群分辨的染色质修饰邻近区分成像分析，2021/07-2022/12，12万元；

（3）主持陕西省自然科学基础研究计划青年项目，2022JQ-092，基于DNA分子标签编码扩增成像的单细胞染色质修饰的精准数字化定量，2022/01-2023/12，5万元；

（4）主持中央高校基本科研业务费-西安交通大学自由探索与创新项目，xzy012022043，基于DNA邻近连接扩增的序列高度相似环状RNA与线性RNA的区分成像，2022/01-2024/12，10万元；

（5）主持中央高校基本科研业务费-西北工业大学新进教师科研启动费，G2024KY05105，基于DNA组合连接编码的淀粉样蛋白聚集精准成像分析，2023.10-2025.09，20万元。

1. 基于微流控芯片的生物传感与生化分析

2. 功能纳米材料在生化检测中的应用

3. 基于DNA纳米技术的单细胞与组织分析

• 陕西高等学校科学技术奖一等奖（排名第六）
  

担任 Springer Nature 旗下期刊 Discover Chemistry 客座编辑

担任Analytical Chemistry, Biosensors and Bioelectronics, Lab Chip, Analytical and Bioanalytical Chemistry, Sensors等国际知名SCI期刊审稿人

中国化学会（CCS）会员

代表性论文（一作/共一）：

[1] Jing Xue^#, Xiao-Wen Cao^#, Xiu-Lan Jia, Xi Chen, Wei-Hong Guo, Da-Chuan Yin*. Visualizing liquid-liquid phase separation and protein aggregates. Communications Chemistry, 2025, Accepted.

[2] Jing Xue^#, Feng Chen^#, Li Su^#, Xiaowen Cao, Min Bai, Yue Zhao, Chunhai Fan, and Yongxi Zhao*. Pairwise Proximity-differentiated Visualization of Single-cell DNA Epigenetic Marks. Angewandte Chemie International Edition, 2021, 60, 3428-3432.

[3] Jing Xue, Feng Chen, Min Bai, Xiaowen Cao,Wenhao Fu, Jin Zhang, and Yongxi Zhao*. Aptamer-Functionalized Microdevices for Bioanalysis. ACS Applied Materials & Interfaces, 2021, 13, 8, 9402-9411.

[4] Jing Xue^#, Feng Chen^#, Min Bai, Xiaowen Cao, Ping Huang, and Yongxi Zhao*. All-in-one Synchronized DNA Nanodevices facilitating multiplexed cell imaging. Analytical Chemistry, 2019, 91, 4696-4701.

[5] Jing Xue, Youlan Fu, Siyue Fan, Xiaowen Cao, Wei Huang, Jin Zhang, Yongxi Zhao and Feng Chen*. Branched immunochip-integrated pairwise barcoding amplification exploring the spatial proximity of two post-translational modifications in distinct cell subpopulations. Chemical Communications, 2022, 58, 10020-10023.

[6] Jing Xue, Feng Chen, Min Bai, Xu Yu, Jing Wei, Ping Huang, Yongxi Zhao*. DNA-Mediated assembly of gold nanoparticles and applications in bioanalysis. ChemNanoMat, 2017, 3: 725-735.

[7] Feng Chen^#, Jing Xue^#, Min Bai, Chunhai Fan and Yongxi Zhao*. Lighting up Nucleic Acid Modifications in Single Cells with DNA-Encoded Amplification. Accounts of Chemical Research, 2022, 55, 2248-2259.

[8] Feng Chen^#, Jing Xue^#, Jin Zhang, Min Bai, Xu Yu, Chunhai Fan and Yongxi Zhao*. Differentiated Visualization of Single-cell 5-Hydroxymethylpyrimidines with Microfluidic Hydrogel Encoding. Journal of the American Chemical Society, 2020, 142, 2889-2896.

[9] Feng Chen^#, Jing Xue^#, Min Bai, Jing Qin, Yongxi Zhao*. Programming in situ accelerated DNA walkers in diffusion-limited microenvironments. Chemical Science, 2019, 10, 3103-3109.

参与论文：

[1] Jin Zhang, Jing Xue, Ningfeng Luo, Feng Chen, Badong Chen* and Yongxi Zhao*. Lab on a Chip, 2023, 23, 1066-1079.

[2] Xiaowen Cao, Feng Chen*, Jing Xue, Yue Zhao, Min Bai and Yongxi Zhao*. Nucleic Acids Research, 2022, 51, e13.

[3] Feng Chen^#, Min Bai^#, Xiaowen Cao, Jing Xue, Yue Zhao, Na Wu, Lei Zhang, Dexin Zhang, and Yongxi Zhao*. Nature Communications, 2021, 12, 1965.

[4] Min Bai^#, Feng Chen^#, Xiaowen Cao, Yue Zhao, Jing Xue, Yongxi Zhao*. Angewandte Chemie International Edition, 2020, 59, 13267-13272.

[5] Feng Chen, Min Bai, Xiaowen Cao, Yue Zhao, Jing Xue and Yongxi Zhao*. Nuceilc Acids Research, 2019, 47, e145.

[6] Min Bai, Xiaowen Cao, Wei Huang, Feng Chen, Yue Zhao, Jing Xue, Youjun Li, Yongxi Zhao*. Analytical Chemistry, 2020, 92, 8444-8449.

[7] Li Su^#, Fengjiao Zhao^#, Huahang Yu, Min Bai, Jing Xue, Xiaowen Cao, Feng Chen and Yongxi Zhao*. Chemical Communications, 2022, 58, 1322-1325.