程冲，四川大学高分子科学与工程学院，教授，博士生导师，国家杰青，国家级青年人才，四川省特聘专家，先进高分子材料全国重点实验室固定人员，洪堡学者。硕博师从四川大学高分子学院赵长生教授，先后在美国密歇根大学安娜堡分校Prof. Nicholas A. Kotov课题组公派博士联合培养及柏林自由大学Prof. Rainer Haag课题组从事博士后研究工作。
团队主要研究方向：高分子基先进催化材料的精确构筑及在纳米医药、组织工程、生物催化等领域的应用开发，特别是基于新型配位聚合物、共轭有机框架等的人造酶催化特性、微纳米结构、多功能设计及临床重大疾病治疗。
团队长期发展目标：1）构筑“有生命的高分子与医学材料”；2）利用高分子及材料基因工程技术解决医学、能源、环境中的困境与挑战。
研究项目与科研成果等：主持国家基金委青A项目、国际合作研究项目及面上项目、国家重点研发计划、四川省重点国际科技创新合作项目，并参与国家重点研发计划干细胞生物材料专项（子课题负责人）。以第一和通讯作者在Nature Materials、Chemical Reviews、Chemical Society Reviews、Nature Communications (9篇)、Science Advances、Journal of the American Chemical Society (4篇)、Advanced Materials (25篇)、Angewandte Chemie (9篇)、Cell Biomaterials、Joule、Materials Today、Nano Today、ACS Nano (7篇)、Nano Letters (3篇)、Advanced Functional Materials (23篇)、Advanced Science (3篇)、InfoMat、Small (10篇)、Nano-Micro Letters、Biomaterials等国内外高水平期刊上发表论文190余篇，共发表论文270余篇，总引用14000余次，H-index为64，其中15篇入选ESI高被引，22篇封面论文。在申及授权中国发明专利45项，欧洲专利1项及PCT专利2项，并参编英文著作1章，担任InfoMat、Nano-Micro Letters、Advanced Fiber Materials、Exploration、Electron、Chinese Chemical Letters等多个国际期刊的杂志青年编委，中国材料研究学会纤维材料改性与复合技术分会第一届理事会常务理事。荣获四川省科学技术进步奖一等奖、四川省科学技术进步奖二等奖、华夏医学科技奖科学技术奖三等奖、四川大学十大基础研究进展奖、四川大学第八届德渥群芳育人文化建设标兵科研团队、四川省医学青年科技奖（二等奖）、川渝科技学术大会优秀论文奖（6项）及四川大学优秀科技人才奖。
课题组常年招收硕士、博士及博士后等，欢迎邮件联系交流，特别支持高分子学科领域优秀大学生通过学校学院的暑期夏令营等进组交流学习，深入了解团队研究领域和科研文化。也非常欢迎本院及外学院相关专业本科生通过大创和学科竞赛等项目进入课题组学习和开展医工结合、双碳战略、人工智能等交叉研究工作。
研究生招生信息：
博士生招生
1）学科专业代码及名称：080502 材料学
① 01 (全日制)聚合物结构与性能
② 02 (全日制)聚合物合成与改性
③ 03 (全日制)高分子材料的高性能化与功能化
④ 04 (全日制)高分子材料加工基础理论与新技术
⑤ 05 (全日制)天然高分子与高分子生物材料的结构与性能
2）学科专业代码及名称：085600 材料与化工（工程博士，01材料工程方向）
硕士生招生
1）学科专业代码及名称：080502 材料学
① 2）学科专业代码及名称：085600 材料与化工（01材料工程方向 或 复试方向为1高分子材料）
团队详细的科研文化、人才培育和招生要求介绍：https://www.x-mol.com/groups/aldm-scu/contact_us
地址：四川大学望江校区高分子学院科教楼505室，邮编610065
Email：chong.cheng@scu.edu.cn, sagecheng@163.com
代表论文：
45. S. Li, B. Chen, Y. Wang,* M.Y. Ye, P.A. van Aken, C. Cheng,* and A. Thomas*, Oxygen-evolving catalytic atoms on metal carbides, Nature Materials, 2021, 20, 1240–1247.
44. R. Li,1 T. Wang,1 S. Mu, Z. Xing, Z. Ding, Q. Wen, Z. Wei, X. Wang, M. Adeli, S. Li, C. Cheng,* and X. Peng,* Bioinspired ruthenium-manganese-oxygen complex for biocatalytic and radiosensitization therapies to eradicate primary and metastatic tumors, Nature Communications, 2025, 16, 7640.
43. J. Yang, Z. Zhao, X. Liu, H. Yang, J. Yang, M. Zhou, S. Li, X. Liu,* X. Xu,* and C. Cheng*, Homologous heteropolyaromatic covalent organic frameworks for enhancing photocatalytic hydrogen peroxide production and aerobic oxidation, Nature Communications, 2025, 16, 7654.
42. C. Yang,1 Y. Gao,1 Z. Xing, X. Shu, Z. Zhuang, Y. Wang, Y. Zheng, S. Li, C. Cheng,* D. Wang,* and J. Zhang,* Bioinspired Sulfo oxygen bridges optimize interfacial water structure for enhanced hydrogen oxidation and evolution reactions, Nature Communications, 2025, 16, 6459.
41. X. Rong,1 S. Xiao,1 W. Geng, B. Zhu, P. Mou, Z. Ding, B. Zhang,* Y. Fan, L. Qiu,* and C. Cheng,* Sono-activable and biocatalytic 3D-printed scaffolds for intelligently sequential therapies in osteosarcoma eradication and defect regeneration, Nature Communications, 2025, 16, 6150.
40. T. Wang,1 M. Bai,1 W. Geng, M. Adeli, L. Ye, C. Cheng,* Bioinspired artificial antioxidases for superior redox homeostasis and maxillofacial bone regeneration, Nature Communications, 2025, 16, 856.
39. M. Bai,1 T. Wang,1 Z. Xing, H. Huang, X. Wu, M. Adeli, M. Wang, X. Han, L. Ye,* C. Cheng,* Electron-donable heterojunctions with synergetic Ru-Cu pair sites for biocatalytic microenvironment modulations in inflammatory mandible defects, Nature Communications, 2024, 15, 9592.
38. M. Fatkullin, D. Cheshev, A. Averkiev, A. Gorbunova, G. Murastov, J. Liu, P. Postnikov, C. Cheng,* R.D. Rodriguez,* E. Sheremet, Photochemistry dominates over photothermal effects in the laser-induced reduction of graphene oxide by visible light, Nature Communications, 2024, 15, 9711.
37. Z. Zhang, Z. Xing, X. Luo, C. Cheng,* X. Liu,* Densely Populated Macrocyclic Dicobalt Sites in Ladder Polymers for Low-Overpotential Oxygen Reduction Catalysis, Nature Communications, 2025, 16, 921.
36. Y.P. Long, L. Li, T. Xu, X.Z. Wu, Y. Gao, J.B. Huang, C. He, T. Ma, L. Ma, C. Cheng,* C.S. Zhao* Hedgehog Artificial Macrophage with Atomic-Catalytic Centers to Combat Drug-Resistant Bacteria, Nature Communications, 2021,12, 6143.
35. C. Nie, M. Stadtmüller, B.Parshad, M. Wallert, V. Ahmadi, Y. Kerkhoff, S. Bhatia, S. Block,* C. Cheng,* T. Wolff,* R. Haag,* Heteromultivalent topology-matched nanostructures as potent and broad-spectrum influenza A virus inhibitors, Science Advances, 2021, 7, eabd3803.
34. S. Cao,1 Y. Long,1 S. Xiao, Y. Deng, L. Ma, M. Adeli, L. Qiu,* C. Cheng,* and C.S. Zhao*, Reactive Oxygen Nanobiocatalysts: Activity-Mechanism Disclosures, Catalytic Center Evolutions, and Changing States, Chemical Society Reviews, 2023, 52, 6838.
33. Y. Xie,1 Q. Li,1 L. Huang, P. Wang, T. Wang, M. Bai, J. Guo, W. Geng, X. Wang, W. Qiao, X. Han,* and C. Cheng,* Spatial Configuration-Guided Design of Covalent Organic Framework-based Artificial Metalloantioxidases for Inhibiting Inflammatory Cascades and Regulating Bone Homeostasis, Journal of the American Chemical Society, 2025, 147, 19113.
32. Y. Lyu,1 Q. Li,1 S. Xie,1 Z. Zhao, L. Ma, Z. Wu, W. Bao, Y. Cai, H. Liu, H. He, K. Xie, F. Gao, Y. Yang, P. Wu, P. He, K. Wang, X. Dai, H. Wu,* T. Lan,* C. Cheng,* Synergistic Ultrasound-Activable Artificial Enzyme and Precision Gene Therapy to Suppress Redox Homeostasis and Malignant Phenotypes for Controllably Combating Hepatocellular Carcinoma, Journal of the American Chemical Society, 2025, 147, 2350.
31. W. Shao,1 Z. Xing,1 X. Xu, D. Ye, R. Yan, T. Ma, Z. Zeng, B. Yin, C. Cheng,* and S. Li*, Bioinspired Proton Pump on Ferroelectric HfO2 Coupled Ir Catalysts with Bidirectional Hydrogen Spillover for pH-Universal and Superior Hydrogen Production, Journal of the American Chemical Society, 2024, 146, 27486–27498.
30. Q. Li,1 Z. Zhao,1 T. Wang, M. Adeli, X. Xu, X. Luo, C. Cheng,* Upgrading the Bioinspired Iron-Polyporphyrin Structures by Abiological Metals Towards New-Generation Reactive Oxygen Biocatalysts, Nano Letters, 2025, 25, 1404.
29. S. Xiao,1 S. Huang,1 M. Wang, T. Wang, M. Han, Y. Deng, W. Geng, L. Cheng, X. Wang, L. Ma,* L. Qiu,* and C. Cheng*, Biocatalytic and Redox-Regulated Nanoarchitectures for Precision Inflammation and Immune Homeostasis Modulation to Combat Rheumatoid Arthritis, Advanced Materials, 2025, 37, 2502147.
28. Q. Li,1 T. Tian,1 W. Geng, X. Huang, X. Xu, M. Adeli, X. Wang, L. Cheng, T. Ma, H. Luo,* L. Ma,* C. Cheng*, Neuroblastoma-Targeting π-Conjugated COP Nanostructure with Multiple Enzyme-Mimetic Actions for Sonochemodynamic Immunotherapies, Advanced Materials, 2025, 37, 2503261.
27. T. Wang,1 Z. Xing,1 M. Wang, C. He, T. Ma, Y. Wang, X. Wang, H. Wu, S. Li, C. Cheng,* and C.S. Zhao, Bioinspired O2-Evolution Catalysts with Proton-Coupled Electron Transfer Pathway for Portable Oxygen Generation, Advanced Materials, 2025, 37, 2502102.
26. J. L. Liu,1 T. Wang,1 C. C. Liao, W. Geng, J. Yang, S. X. Ma, W. D. Tian, L. Liao,* C. Cheng,* Constructing Electron-Rich Ru Clusters on Non-Stoichiometric Copper Hydroxide for Superior Biocatalytic ROS Scavenging to Treat Inflammatory Spinal Cord Injury, Advanced Materials, 2024, 36, 2411618.
25. S. Xiao,1 L. Xie,1 Y. Gao, M. Wang, W. Geng, X. Wu, R.D. Rodriguez, L. Cheng, L. Qiu,* and C. Cheng*, Artificial Phages with Biocatalytic Spikes for Synergistically Eradicating Antibiotic-Resistant Biofilms, Advanced Materials, 2024, 36, 2404411.
24. Q. Li,1 Z. Zhao,1 F. Chen,1 X. Xu, L. Xu, L. Cheng, M. Adeli, X. Luo, C. Cheng*, Delocalization Engineering of Heme-Mimetic Artificial Enzymes for Augmented Reactive Oxygen Catalysis, Angew. Chem. Int. Ed., 2024, 63, e202400838.
23. H. Huang, W. Geng, X. Wu, Y. Zhang, L. Xie, T. Ma, C. Cheng*, Spiky Artificial Peroxidases with V–O–Fe Pair Sites for Combating Antibiotic-Resistant Pathogens, Angew. Chem. Int. Ed., 2024, 63, e202310811.
22. L. Li, Q. Wen, T. Wang, S. Xiao, Y. Gao, M. Wang, X. Xu,* L. Ma,* and C. Cheng,* Metal-Organic Frameworks-Engineered Reactive-Oxygen Catalytic Materials: Enzyme-Mimicking Coordinations, Structure Evolutions, and Biotherapeutic Applications, Materials Today, 2024, 78, 142-180.
21. Y. Gao,1 Y. Deng,1 W. Geng, S. Xiao, T. Wang, X. Xu, M. Adeli, L. Cheng, L. Qiu,* and C. Cheng,* Infectious and Inflammatory Microenvironment Self-Adaptive Artificial Peroxisomes with Synergetic Co-Ru Pair Centers for Programmed Diabetic Ulcer Therapy, Advanced Materials, 2024, 36, 2408787.
20. X. Wu,1 Z. Xing,1 H. Huang, Z. Ding, Y. Gao, L. Ma, T. Ma,* C. Cheng,* and C.S. Zhao*, Bacteriophage-like Nanobiocatalysts with Spiky Topography and Dual-Atom Sites for Treating Drug-Resistant Bacteria, ACS Nano, 2024, 18, 26168–26183.
19. X. Huang,1 H. Zhou,1 N. Lv, Z. Zhao, T. Tian, J. Huang, R.D. Rodriguez, H. Luo,* C. Cheng,* L. Ma,* Immunomodulating Sonocatalytic Nanoagents with Dual-Functional Ir-N Centers and Narrow Bandgap for Reversing Immunosuppression and Potentiating Ovarian Cancer Immunotherapy, Advanced Functional Materials, 2024, 34, 2407349.
18. X. Wang,1 Q. Li,1 Z. Zhao, L. Yu, S. Wang, H. Pu, M. Adeli, L. Qiu, P. Gu,* L. Li,* C. Cheng*, Dual-Functional Artificial Peroxidases with Ferriporphyrin Centers for Amplifying Tumor Immunotherapies via Immunogenic Cell Death, Advanced Functional Materials, 2024, 34, 2313143.
17. Z. Wu,1 Y. Sun,1 S. Mu, M. Bai, Q. Li, T. Ma, L. Ma, F. Chen, X. Luo, L. Ye,* C. Cheng*, Manganese-based Antioxidase-Inspired Biocatalysts with Axial Mn-N5 Sites and 2D d-π-Conjugated Networks for Rescuing Stem Cell Fates, Angew. Chem. Int. Ed., 2023, 62, e202302329.
16. Y. Deng,1 Y. Gao,1 T. Li, S. Xiao, M. Adeli, R.D. Rodriguez, Q. Chen,* W. Geng,* C. Cheng,* C.S. Zhao, Amorphizing Metal Selenides-based ROS Biocatalysts at Surface Nanolayer towards Ultrafast Inflammatory Diabetic Wound Healing, ACS Nano, 2023, 17, 2943.
15. Y. Sun,1 S. Mu,1 Z. Xing, J. Guo, Z. Wu, F. Yu, M. Bai, X. Han, C. Cheng,* and L. Ye*, Catalase-Mimetic Artificial Biocatalysts with Ru Catalytic Centers for ROS Elimination and Stem-Cell Protection, Advanced Materials, 2022, 34, 2206208.
14. T. Ma,1 H. Cao,1 S. Li, S. Cao, Z. Zhao, Z. Wu, R. Yan, M. Cheng, C. Yang, Y. Gao, L. Ma, Y. Wang,* P. A. van Aken, L. Qiu,* Y. Wang,* and C. Cheng,* Crystalline Lattice-Confined Atomic Pt in Metal Carbides to Match Electronic Structures and Hydrogen Evolution Behaviors of Platinum, Advanced Materials, 2022, 34, 2206368.
13. S. Cao, Z. Zhao, Y. Zheng, Z. Wu, T. Ma, B. Zhu, C. Yang, X. Xiang, L. Ma, X. Han, Y. Wang*, Q. Guo, L. Qiu*, and C. Cheng*, A Library of ROS-Catalytic Metalloenzyme-Mimics with Atomic Metal Centers, Advanced Materials, 2022, 34, 2200255.
12. X. Fan, X. Wu, F. Yang, L. Wang, K. Ludwig, L. Ma, A. Trampuz,* C. Cheng,* and R. Haag*, A Nanohook-Equipped Bionanocatalyst for Localized Near-Infrared-Enhanced Catalytic Bacterial Disinfection, Angew. Chem. Int. Ed. 2022, 61, e202113833.
11. B. Zhang, Z. Wu, W. Shao, Y. Gao, W. Wang, T. Ma, L. Ma, S. Li,* C. Cheng,* C.S. Zhao* Interfacial Atom-Substitution Engineered Transition-Metal Hydroxide Nanofibers with High-Valence Fe for Efficient Electrochemical Water Oxidation, Angew. Chem. Int. Ed. 2022, 61, e202115331.
10. F.X. Du,1 L.C. Liu,1 Z.H. Wu, Z.Y. Zhao, W. Geng, B.H. Zhu, T. Ma, X. Xiang, L. Ma, C. Cheng,* and L. Qiu*, Pd-Single-Atom Coordinated Biocatalysts for Chem-/Sono-/Photo-Trimodal Tumor Therapies, Advanced Materials, 2021, 33, 2101095.
9. X. Fan, F. Yang, C.X. Nie, L. Ma,* C. Cheng,* and R. Haag*, Biocatalytic Nanomaterials: A New Pathway for Bacterial Disinfection, Advanced Materials, 2021, 33, 2100637.
8. Y. Gao,1 T. Wu,1 C. Yang,1 C. Ma, Z. Zhao, Z. Wu, S. Cao, W. Geng, Y. Wang, Y. Yao,* Y. Zhang,* C. Cheng,* Activity Trends and Mechanisms in Peroxymonosulfate-Assisted Catalytic Production of Singlet Oxygen over Atomic Metal-N-C Catalysts, Angew. Chem. Int. Ed. 2021, 60, 22513.
7. B. Zhang,1 Y. Zheng,1 T. Ma, C. Yang, Y. Peng, Z. Zhou, M. Zhou, S. Li,* Y. Wang,* C. Cheng,* Designing MOF Nanoarchitectures for Electrochemical Water Splitting, Advanced Materials, 2021, 33, 2006042.
6. Y. Yang,1 X. Wu,1 L. Ma, C. He, S. Cao, Y. Long, J. Huang, R.D. Rodriguez, C. Cheng,* C.S. Zhao,* L. Qiu,* Bioinspired Spiky Peroxidase-Mimics for Localized Bacterial Capture and Synergistic Catalytic Sterilization, Advanced Materials, 2021, 33, 2005477.
5. Nie, C.; Stadtmüller, M.; Yang, H.; Xia, Y.; Wolff, T.;* Cheng, C.;* Haag, R.,* Spiky Nanostructures with Geometry-matching Topography for Virus Inhibition. Nano Letters 2020, 20 (7), 5367-5375.
4. Fan X.; Yang F.; Huang J.; Yang Y.; Nie C.; Zhao W.F.; Ma L.;* Cheng C.;* Zhao C.S.;* Haag R., Metal–Organic-Framework-Derived 2D Carbon Nanosheets for Localized Multiple Bacterial Eradication and Augmented Anti-infective Therapy, Nano Letters 2019, 19 (9), 5885-5896.
3. Cheng, C.*; Li, S.; Xia, Y.; Ma, L.; Nie, C.; Roth, C.; Thomas, A.; Haag, R.*, Atomic Fe–Nx Coupled Open-Mesoporous Carbon Nanofibers for Efficient and Bioadaptable Oxygen Electrode in Mg–Air Batteries. Advanced Materials 2018, 30, 1802669.
2. Cheng, C.*; Zhang, J.; Li, S.; Xia, Y.; Nie, C.; Shi, Z.; Cuellar-Camacho, J. L.; Ma, N.; Haag, R.*, A Water-Processable and Bioactive Multivalent Graphene Nanoink for Highly Flexible Bioelectronic Films and Nanofibers. Advanced Materials 2018, 30 (5), 1705452.
1. Cheng, C.*; Li, S.; Thomas, A.; Kotov, N. A.; Haag, R., Functional Graphene Nanomaterials Based Architectures: Biointeractions, Fabrications, and Emerging Biological Applications. Chemical Reviews 2017, 117 (3), 1826-1914.
