曾嘉发：

暨南大学 临床医学博士后流动站在站博士后

邮箱：zengfone@163.com

研究方向：

呼气代谢组学在药物监测、疾病诊断等方向的临床应用

主要教育经历：

2020.10 – 2024.10——瑞士巴塞尔大学——博士学位（生物医学工程专业）

2017.09 – 2020.07——暨南大学——硕士学位（环境科学专业）

2012.09 – 2016.07——华南农业大学——学士学位（能源与环境系统工程专业）

主要工作经历：   

发表论文：

[1]  Zeng, J.; Stankovic, N.; Singh, K. D.; Frey, U.; Erb, T.; Sinues, P., Breath Analysis of Propofol and Associated Metabolic Signatures: A Pilot Study Using Secondary Electrospray Ionization-High-resolution Mass Spectrometry. ANESTHESIOLOGY, 2025.

[2]  Zeng, J.; Usemann, J.; Singh, K. D.; Jochmann, A.; Trachsel, D.; Frey, U.; Sinues, P., Pharmacometabolomics via real-time breath analysis captures metabotypes of asthmatic children associated with salbutamol responsiveness. iScience, 2024, 27(12), 111446.

[3]  Awchi, M.; Singh, K. D.; Brenner, S. B.; Burckhardt, M.-A.; Hess, M.; Zeng, J.; Datta, A. N.; Frey, U.; Zumsteg, U.; Szinnai, G.; Sinues, P., Metabolic Trajectories of Diabetic Ketoacidosis Onset Described by Breath Analysis. Frontiers in Endocrinology, 2024, 15, 1360989.

[4]  Sola-Martinez, R. A.; Zeng, J.; Awchi, M.; Gisler, A.; Arnold, K.; Singh, K. D.; Frey, U.; Diaz, M. C.; de Diego Puente, T.; Sinues, P., Preservation of Exhaled Breath Samples for Analysis by Off-Line Sesi-Hrms: Proof-of-Concept Study. Journal of Breath Research, 2023, 18.

[5]  Zeng, J.; Christen, A.; Singh, K. D.; Frey, U.; Sinues, P., Comparison of Plasma Ionization-and Secondary Electrospray Ionization-High-Resolution Mass Spectrometry for Real-Time Breath Analysis. Chimia, 2022, 76, 127–127.

[6]  Gisler, A.; Singh, K. D.; Zeng, J., et al., An Interoperability Framework for Multicentric Breath Metabolomic Studies. iScience, 2022, 25, 105557.

[7]  Xu, X.^†, Zeng, J. ^†, Jin, D., Huang, Z., Li, L., Wexler, A., Chan, M., Zhou, Z., Li, Y., Li, X. Insights on the working principles of secondary electrospray ionization high-resolution mass spectrometry for quantitative analysis of aerosol chemical composition. Aerosol Science and Engineering, 2021, 5, 147-155.

[8]  Decrue, F.; Singh, K. D.; Gisler, A.; Awchi, M.; Zeng, J.; Usemann, J.; Frey, U.; Sinues, P., Combination of Exhaled Breath Analysis with Parallel Lung Function and Feno Measurements in Infants. ANALYTICAL CHEMISTRY, 2021, 93, 15579–15583.

[9]  Liu, C.; Zeng, J.; Sinues, P.; Fang, M.; Zhou, Z.; Li, X., Quantification of Volatile Organic Compounds by Secondary Electrospray Ionization-High Resolution Mass Spectrometry. Analytica Chimica Acta, 2021, 1180, 338876.

[10]  Zeng, J.; Mekic, M.; Xu, X.; Loisel, G.; Zhou, Z.; Gligorovski, S.; Li, X., A Novel Insight into the Ozone–Skin Lipid Oxidation Products Observed by Secondary Electrospray Ionization High-Resolution Mass Spectrometry. Environmental Science & Technology, 2020, 54, 13478–13487.

[11]  Zeng, J. ^†; Yu, Z. ^†; Mekic, M. ^†; Liu, J.; Li, S.; Loisel, G.; Gao, W.; Gandolfo, A.; Zhou, Z.; Wang, X.; Herrmann, H.; Gligorovski, S.; Li, X., Evolution of Indoor Cooking Emissions Captured by Using Secondary Electrospray Ionization High-Resolution Mass Spectrometry. Environmental Science & Technology Letters, 2020, 7, 76–81.

[12]  Mekic, M.; Zeng, J.; Zhou, W.; Loisel, G.; Jin, B.; Li, X.; Vione, D.; Gligorovski, S., Ionic Strength Effect on Photochemistry of Fluorene and Dimethylsulfoxide at the Air–Sea Interface: Alternative Formation Pathway of Organic Sulfur Compounds in a Marine Atmosphere. ACS Earth and Space Chemistry, 2020, 4, 1029–1038.

[13]  Liu, J.^†; Li, S.^†; Zeng, J.^†; Mekic, M.; Yu, Z.; Zhou, W.; Loisel, G.; Gandolfo, A.; Song, W.; Wang, X., Assessing Indoor Gas Phase Oxidation Capacity through Real-Time Measurements of Hono and No X in Guangzhou, China. Environmental Science-Processes & Impacts, 2019, 21, 1393–1402.

[14]  Li, X.; Huang, D.; Zeng, J.; Chan, C. K.; Zhou, Z., Positive Matrix Factorization: A Data Preprocessing Strategy for Direct Mass Spectrometry-Based Breath Analysis. TALANTA, 2019, 192, 32–39.

[15]  Du, R.; Zhang, Y.; Zeng, J.; Fang, M.; Gligorovski, S.; Zhou, Z.; Li, X, Influence of Ambient Gases on Detection of Exhaled Gas in Secondary Electrospray Source by Ultra-High Resolution Mass Spectrometry. Chinese Journal of Analytical Chemistry, 2019, 47, 916–924. 

荣誉与奖励：