Computational Biology and Chemistry publishes original research papers and review articles in all areas of computational life sciences. High quality research contributions with a major computational component in the areas of nucleic acid and protein sequence research, molecular evolution, molecular genetics (functional genomics and proteomics), theory and practice of either biology-specific or chemical-biology-specific modeling, and structural biology of nucleic acids and proteins are particularly welcome. Exceptionally high quality research work in bioinformatics, systems biology, ecology, computational pharmacology, metabolism, biomedical engineering, epidemiology, and statistical genetics will also be considered. 

Given their inherent uncertainty, protein modeling and molecular docking studies should be thoroughly validated. In the absence of experimental results for validation, the use of molecular dynamics simulations along with detailed free energy calculations, for example, should be used as complementary techniques to support the major conclusions. Submissions of premature modeling exercises without additional biological insights will not be considered. 

Review articles will generally be commissioned by the editors and should not be submitted to the journal without explicit invitation. However prospective authors are welcome to send a brief (one to three pages) synopsis, which will be evaluated by the editors. 

original research papers and review articles 

Editors
Wentian Li
The R.S. Boas Ctr for Genomics & Human Gentics, The Feinstein Institute for Medical Research, Manhasset, NY, United States Email Wentian Li
Donald Hamelberg
Georgia State University, Atlanta, Georgia, United States Email Donald Hamelberg
Associate Editor
Qin Ma
OHIO STATE UNIVERSITY, Columbus, Ohio, United States
Founding Editor
M.J.C. Crabbe
University of Bedfordshire, Luton, United Kingdom
A.K. Konopka
Biolingua Research Inc, Gaithersburg, Maryland, United States
Editorial Board
Peter Arndt
Berlin, Germany
Alexander Bolshoy
Haifa, Israel
Philipp Bucher
Lausanne, Switzerland
Maxime Crochemore
London, United Kingdom
Jan Freudenberg
Manhasset, New York, United States
Kay Hofmann
Koln, Germany
Lilia Iakoucheva
La Jolla, California, United States
Sophia Kossida
Montpellier, France
Pietro Lio
Cambridge, United Kingdom
Frederique Lisacek
Geneva, Switzerland
Bingqiang Liu
Weihai, China
Robert Macgregor
Toronto, Ontario, Canada
Vsevolod Makeev
Moskva, Russian Federation
J. Andrew McCammon
La Jolla, California, United States
Bud Mishra
New York, New York, United States
Graziano Pesole
Bari, Italy
Ch. Mohan Rao
Hyderabad, India
Andrzej Sokalski
Wroclaw, Poland
John Spouge
Bethesda, Maryland, United States
William R. Taylor
London, United Kingdom
Hendrik Viljoen
Lincoln, Nebraska, United States
Eberhard Voit
Atlanta, Georgia, United States
Yan Wang
Changchun, China
Anru Zhang
Madison, Wisconsin, United States
Chi Zhang
Indianapolis, Indiana, United States
Jim Zheng
Houston, Texas, United States
Quan Zou
Chengdu, China