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Surface Engineering of Nanoparticles toward Cancer Theranostics.Accounts of chemical research, 2023, 10.1021/acs.accounts.3c00122. Advance online publication.Huang, P., Wang, C., Deng, H., Zhou, Y., & Chen, X.
Hybrid Biomimetic Membrane Coated Particles-Mediated Bacterial Ferroptosis for Acute MRSA Pneumonia.ACS nano, 10.1021/acsnano.3c02365. Advance online publication.Hu, H., Hua, S. Y., Lin, X., Lu, F., Zhang, W., Zhou, L., Cui, J., Wang, R., Xia, J., Xu, F., Chen, X., & Zhou, M. (2023).
Dual targeting PET tracer [68Ga]Ga-FAPI-RGD in patients with lung neoplasms: a pilot exploratory study.Theranostics, 2023, 13(9), 2979–2992.Wang, R., Jakobsson, V., Wang, J., Zhao, T., Peng, X., Li, B., Xue, J., Liang, N., Zhu, Z., Chen, X., & Zhang, J.
Rapid Tumor Washout of 177Lu-PSMA Radioligand in Renal Cell Carcinoma.Clinical nuclear medicine, 2023, 10.1097/RLU.0000000000004725. Advance online publication.Zhang, J., Schuchardt, C., Chen, X., & Baum, R. P.
Gas therapy potentiates aggregation-induced emission luminogen-based photoimmunotherapy of poorly immunogenic tumors through cGAS-STING pathway activation Nature communications, 2023, 14(1), 2950.Wang, K., Li, Y., Wang, X., Zhang, Z., Cao, L., Fan, X., Wan, B., Liu, F., Zhang, X., He, Z., Zhou, Y., Wang, D., Sun, J., & Chen, X.
Tuning the Organ Tropism of Polymersome for Spleen-Selective Nanovaccine Delivery to Boost Cancer Immunotherapy.Advanced materials (Deerfield Beach, Fla.), e2301686.Gu, W., An, J., Li, Y., Yang, Y., Wang, S., Shan, H., Li, S., Li, H., Liu, G., Li, K., Yin, Y., Mu, J., & Chen, X.
Orchestrated strategies for developing fluorophores for NIR-II imaging.Advanced healthcare materials, e2300537.Feng, X., Wei, L., Liu, Y., Chen, X., & Tian, R.
Tumor-microenvironment-responsive poly-prodrug encapsulated semiconducting polymer nanosystem for phototherapy-boosted chemotherapy.Materials horizons, 2023, 10.1039/d3mh00242j. Zhu, J., Zhang, Y., Li, Z., Bao, X., Zhou, Y., Ma, B., Xie, Y., Yan, P., Wu, Z., Zhang, Q., Zou, J., & Chen, X.
Clinical Evaluation of 68Ga-FAPI-RGD for Imaging of Fibroblast Activation Protein and Integrin αvβ3 in Various Cancer Types.Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2023, jnumed.122.265383. Advance online publication. Zhao, L., Wen, X., Xu, W., Pang, Y., Sun, L., Wu, X., Xu, P., Zhang, J., Guo, Z., Lin, Q., Chen, X., & Chen, H.
Gas-Mediated Tumor Energy Remodeling for Sensitizing Mild Photothermal Therapy.Angewandte Chemie (International ed. in English), 2023, e202304312. Advance online publication.Cheng, J., Zhu, Y., Dai, Y., Li, L., Zhang, M., Jin, D., Liu, M., Yu, J., Yu, W., Su, D., Zou, J., Chen, X., & Liu, Y.
Development of [177Lu]Lu-LNC1003 for radioligand therapy of prostate cancer with a moderate level of PSMA expression.European journal of nuclear medicine and molecular imaging, 2023, 10.1007/s00259-023-06229-w. Advance online publication.Wen, X., Xu, P., Zeng, X., Liu, J., Du, C., Zeng, X., Cheng, X., Wang, X., Liang, Y., Zhao, T., Yang, H., Li, H., Meng, L., Fang, J., Liu, H., Zhou, Z., Zhang, J., Zhang, X., Guo, Z., & Chen, X.
Ligustrazine Nanoparticle Hitchhiking on Neutrophils for Enhanced Therapy of Cerebral Ischemia-Reperfusion Injury.Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2023, e2301348.Mu, Q., Yao, K., Syeda, M. Z., Zhang, M., Cheng, Q., Zhang, Y., Sun, R., Lu, Y., Zhang, H., Luo, Z., Huang, H., Liu, X., Luo, C., Zhu, X., Wu, S., Cui, L., Huang, C., Chen, X., & Tang, L.
Evaluation of Safety, Biodistribution, and Dosimetry of a Long-Acting Radiolabeled Somatostatin Analog 177Lu-DOTA-EB-TATE With and Without Amino Acid Infusion Clinical nuclear medicine, 2023, 10.1097/RLU.0000000000004642. Advance online publication.Jiang, Y., Liu, Q., Wang, G., Zhang, J., Zhu, Z., & Chen, X.
Activatable NIR-II Photothermal Lipid Nanoparticles for Improved Messenger RNA Delivery Angewandte Chemie (International ed. in English), 2023, e202302676. Advance online publication.Li, B., Zhao, M., Lai, W., Zhang, X., Yang, B., Chen, X., & Ni, Q.
Engineering Single-Atom Nanozymes for Catalytic Biomedical Applications.Small 2023, (Weinheim an der Bergstrasse, Germany), e2300750. Advance online publication. Zhu, Y., Liao, Y., Zou, J., Cheng, J., Pan, Y., Lin, L., & Chen, X.
Milk-derived extracellular vesicles protect intestinal barrier integrity in the gut-liver axis.Science advances, 2023， 9(15), eade5041.Tong, L., Zhang, S., Liu, Q., Huang, C., Hao, H., Tan, M. S., Yu, X., Lou, C. K. L., Huang, R., Zhang, Z., Liu, T., Gong, P., Ng, C. H., Muthiah, M., Pastorin, G., Wacker, M. G., Chen, X., Storm, G., Lee, C. N., Zhang, L.,H. Yi, Wang, J. W.
Water-Soluble Au25 Clusters with Single-Crystal Structure for Mitochondria-Targeting Radioimmunotherapy.ACS nano, 10.1021/acsnano.3c01068. Advance online publication.Hua, Y., Shao, Z. H., Zhai, A., Zhang, L. J., Wang, Z. Y., Zhao, G., Xie, F., Liu, J. Q., Zhao, X., Chen, X., & Zang, S. Q.
Materials engineering strategies for cancer vaccine adjuvant development.Chemical Society reviews, 10.1039/d2cs00647b. Advance online publication. Zhang, X., Yang, B., Ni, Q., & Chen, X.
Integrative network-based analysis on multiple Gene Expression Omnibus datasets identifies novel immune molecular markers implicated in non-alcoholic steatohepatitis Frontiers in endocrinology, 2023， 14, 1115890. Zhang, J. J., Shen, Y., Chen, X. Y., Jiang, M. L., Yuan, F. H., Xie, S. L., Zhang, J., & Xu, F.
Aspartate beta-hydroxylase domain containing 1 as a prognostic marker associated with immune infiltration in skin cutaneous melanoma BMC cancer, 2023，23(1), 292. Sun, S., Deng, M., Wen, J., Chen, X., Xu, J., Liu, Y., Wan, H., Wang, J., Yan, L., He, Y., & Xu, Y.
Artificial-enzymes-armed Bifidobacterium longum probiotics for alleviating intestinal inflammation and microbiota dysbiosis.Nature nanotechnology, 2023, 10.1038/s41565-023-01346-x. Advance online publication.Cao, F., Jin, L., Gao, Y., Ding, Y., Wen, H., Qian, Z., Zhang, C., Hong, L., Yang, H., Zhang, J., Tong, Z., Wang, W., Chen, X., & Mao, Z.
Iron-siRNA Nanohybrids for Enhanced Chemodynamic Therapy via Ferritin Heavy Chain Downregulation.Angewandte Chemie (International ed. in English), e202302255. Advance online publication.Wang, J., Ding, H., Zhu, Y., Liu, Y., Yu, M., Cai, H., Ao, R., Huang, H., Gong, P., Liao, Y., Chen, Z., Lin, L., Chen, X., & Yang, H.
Engineered Toll-like Receptor Nanoagonist Binding to Extracellular Matrix Elicits Safe and Robust Antitumor Immunity.ACS nano, 2023, 17(6), 5340–5353.Yang, L., Lang, Y., Wu, H., Xiang, K., Wang, Y., Yu, M., Liu, Y., Yang, B., He, L., Lu, G., Ni, Q., Chen, X., & Zhang, L.
Harnessing Nanomaterials for Cancer Sonodynamic Immunotherapy.Advanced materials (Deerfield Beach, Fla.), e2211130. Advance online publication.Liang, S., Yao, J., Liu, D., Rao, L., Chen, X., & Wang, Z. (2023).
Ferroptosis MRI for early detection of anticancer drug-induced acute cardiac/kidney injuries.Science advances, 9(10), eadd8539.Zeng, F., Nijiati, S., Liu, Y., Yang, Q., Liu, X., Zhang, Q., Chen, S., Su, A., Xiong, H., Shi, C., Cai, C., Lin, Z., Chen, X., & Zhou, Z.
In Situ Transformable Nanoplatforms with Supramolecular Crosslinking Triggered Complementary Function for Enhanced Cancer Photodynamic Therapy.Advanced materials (Deerfield Beach, Fla.), 2023, e2209944. Advance online publication.Zhao, M., Zhuang, H., Li, B., Chen, M., & Chen, X.
Transition Metal-based Therapies for Inflammatory Diseases.Advanced materials (Deerfield Beach, Fla.), 2023, e2212102. Advance online publication.Song, Y., You, Q., & Chen, X.
Exosomal STIMATE derived from type II alveolar epithelial cells controls metabolic reprogramming of tissue-resident alveolar macrophages.Theranostics, 13(3), 991–1009.Feng, Z., Jing, Z., Li, Q., Chu, L., Jiang, Y., Zhang, X., Yan, L., Liu, Y., Jiang, J., Xu, P., Chen, Q., Wang, M., Yang, H., Zhou, G., Jiang, X., Chen, X., & Xia, H.
Ferroptosis Detection: From Approaches to Applications Angewandte Chemie (International ed. in English), e202300379. Advance online publication.Zeng, F., Nijiati, S., Tang, L., Ye, J., Zhou, Z., & Chen, X.
Ultra-wideband-responsive photon conversion through co-sensitization in lanthanide nanocrystals.Nature communications, 14(1), 827.Jiang, Z., He, L., Yang, Z., Qiu, H., Chen, X., Yu, X., & Li, W.
Boosting Checkpoint Immunotherapy with Biomaterials.ACS Nano. 2023 Feb 6. doi: 10.1021/acsnano.2c11691.Liu L, Pan Y, Zhao C, Huang P, Chen X, Rao L.
Peptide Receptor Radionuclide Therapy in Patients With Advanced Progressive Medullary Thyroid Cancer: Efficacy, Safety, and Survival Predictors.Clin Nucl Med. 2023 Mar 1;48(3):221-227.Liu Q, Kulkarni HR, Zhao T, Schuchardt C, Chen X, Zhu Z, Zhang J, Baum RP.
Vesicular Antibodies: Shedding Light on Antibody Therapeutics with Cell Membrane Nanotechnology.Adv Mater. 2023 Jan 31:e2207875.Zhao C, Pan Y, Yu G, Zhao XZ, Chen X, Rao L.
Boosting Ferroptosis Therapy with Iridium Single Atom Nanocatalyst in Ultra-low Metal Content.Adv Mater. 2023 Jan 31:e2210037.Cheng J, Li L, Jin D, Dai Y, Zhu Y, Zou J, Liu M, Yu W, Yu J, Sun Y, Chen X, Liu Y.
Amplification of Lipid Peroxidation by Regulating Cell Membrane Unsaturation to Enhance Chemodynamic Therapy.Angew Chem Int Ed Engl. 2023 Jan 28.Zhu Y, Gong P, Wang J, Cheng J, Wang W, Cai H, Ao R, Huang H, Yu M, Lin L, Chen X.
Fluorescence Imaging-Incorporated Transcriptome Study of Glutathione Depletion-Enhanced Ferroptosis Therapy via Targeting Gold Nanoclusters.ACS Appl Mater Interfaces. 2023 Jan 27. doi: 10.1021/acsami.2c18289.Zhao D, Huang X, Tian Y, Zou J, Wang F, Chen X.
Enhancing Catalytic Activity of a Nickel Single Atom Enzyme by Polynary Heteroatom Doping for Ferroptosis-Based Tumor Therapy.ACS Nano. 2023 Jan 16. doi: 10.1021/acsnano.2c11923.Zhu Y, Wang W, Gong P, Zhao Y, Pan Y, Zou J, Ao R, Wang J, Cai H, Huang H, Yu M, Wang H, Lin L, Chen X, Wu Y.
Tumor polyamines as guest cues attract host-functionalized liposomes for targeting and hunting via a bio-orthogonal supramolecular strategy Theranostics. 2023 Jan 1;13(2):611-620.Cheng Q, Yang Z, Quan X, Ding Y, Li J, Wang Z, Zhao Y, Chen X, Wang R.
Mace-Like Plasmonic Au-Pd Heterostructures Boost Near-Infrared Photoimmunotherapy Adv Sci (Weinh). 2023 Jan 4;e2204842 Yanlin Feng, Xin Ning, Jianlin Wang, Zhaoyang Wen, Fangfang Cao, Qing You, Jianhua Zou, Xin Zhou, Teng Sun, Jimin Cao, Xiaoyuan Chen
Alpha-peptide receptor radionuclide therapy using actinium-225 labeled somatostatin receptor agonists and antagonists Front Med (Lausanne). 2022 Dec 7;9:1034315 Mengqi Shi, Vivianne Jakobsson, Lukas Greifenstein, Pek-Lan Khong, Xiaoyuan Chen, Richard P Baum, Jingjing Zhang
PET imaging of fibroblast activation protein in various types of cancers by using 68Ga-FAP-2286: Comparison with 18F-FDG and 68Ga-FAPI-46 in a single-center, prospective study.J Nucl Med. 2022 Sep 2:jnumed.122.264544.Pang Y, Zhao L, Meng T, Xu W, Lin Q, Wu H, Zhang J, Chen X, Sun L, Chen H.
Synergism of 64Cu-Labeled RGD with Anti-PD-L1 Immunotherapy for the Long-Acting Antitumor Effect.Bioconjug Chem. 2022 Nov 16;33(11):2170-2179.Wen X, Zeng X, Liu J, Zhang Y, Shi C, Wu X, Zhuang R, Chen X, Zhang X, Guo Z.
Development of a multi-scene universal multiple wavelet-FFT algorithm (MW-FFTA) for denoising motion artifacts in OCT-angiography in vivo imaging.Opt Express. 2022 Sep 26;30(20):35854-35870.Zhang Y, Li J, Liu C, Zheng K, Zhang B, Zhou Y, Dai C, Fan S, Yao Y, Zhuang R, Guo D, Huang Z, Mao J, Liang J, Yang H, Wang L, Liu G, Chen X, Zhao Q.
A Totipotent "All-In-One" Peptide Sequentially Blocks Immune Checkpoint and Reverses the Immunosuppressive Tumor Microenvironment.Adv Mater. 2022 Oct 19:e2207330.Zhang L, Jiang Z, Yang X, Qian Y, Wang M, Wu S, Li L, Jia F, Wang Z, Hu Z, Zhao M, Tang X, Li G, Shang H, Chen X, Wang W.
Near-infrared-II ratiometric fluorescence probes for non-invasive detection and precise navigation surgery of metastatic sentinel lymph nodes.Theranostics. 2022 Oct 9;12(16):7191-7202.Li M, Zheng X, Han T, Ma S, Wang Y, Sun B, Xu J, Wang X, Zhang S, Zhu S, Chen X.
Synthesis, preclinical evaluation and radiation dosimetry of a dual targeting PET tracer [68Ga]Ga-FAPI-RGD.Theranostics. 2022 Oct 9;12(16):7180-7190.Zang J, Wen X, Lin R, Zeng X, Wang C, Shi M, Zeng X, Zhang J, Wu X, Zhang X, Miao W, Xu P, Guo Z, Zhang J, Chen X.
Cell Wall Destruction and Internal Cascade Synergistic Antifungal Strategy for Fungal Keratitis.ACS Nano. 2022 Nov 22;16(11):18729-18745. Ye Y, He J, Wang H, Li W, Wang Q, Luo C, Tang X, Chen X, Jin X, Yao K, Zhou M.
Biomimetic Yolk-Shell Nanocatalysts for Activatable Dual-Modal-Image-Guided Triple-Augmented Chemodynamic Therapy of Cancer.ACS Nano. 2022 Nov 22;16(11):19038-19052.Pan Y, Zhu Y, Xu C, Pan C, Shi Y, Zou J, Li Y, Hu X, Zhou B, Zhao C, Gao Q, Zhang J, Wu A, Chen X, Li J.
An Integrated Polymeric mRNA Vaccine without Inflammation Side Effects for Cellular Immunity Mediated Cancer Therapy.Adv Mater. 2022 Nov 3:e2207471 Huang P, Jiang L, Pan H, Ding L, Zhou B, Zhao M, Zou J, Li B, Qi M, Deng H, Zhou Y, Chen X.
A single-arm, low-dose, prospective study of 177Lu-EB-PSMA radioligand therapy in patients with metastatic castration-resistant prostate cancer.J Nucl Med. 2022 Nov 3:jnumed.122.264857.Wang G, Zang J, Jiang Y, Liu Q, Sui H, Wang R, Fan X, Zhang J, Zhu Z, Chen X.
Development of nanotechnology-mediated precision radiotherapy for anti-metastasis and radioprotection.Chem Soc Rev. 2022 Nov 28;51(23):9759-9830. Pan Y, Tang W, Fan W, Zhang J, Chen X.
Responsive Accumulation of Nanohybrids to Boost NIR-Phototheranostics for Specific Tumor Imaging and Glutathione Depletion-Enhanced Synergistic Therapy.Adv Sci (Weinh). 2022 Nov 14;10(1):e2205208.He L, Zheng N, Wang Q, Du J, Wang S, Cao Z, Wang Z, Chen G, Mu J, Liu S, Chen X.
Facile Synthesis of Weakly Ferromagnetic Organogadolinium Macrochelates-Based T1 -Weighted Magnetic Resonance Imaging Contrast Agents.Adv Sci (Weinh). 2022 Nov 15;10(1):e2205109.Lu Y, Liang Z, Feng J, Huang L, Guo S, Yi P, Xiong W, Chen S, Yang S, Xu Y, Li Y, Chen X, Shen Z.
In Response to Precision Medicine: Current Subcellular Targeting Strategies for Cancer Therapy.Adv Mater. 2022 Nov 29:e2209529 Li Z, Zou J, Chen X.
Targeting the activity of T cells by membrane surface redox regulation for cancer theranostics Nat Nanotechnol. 2022 Dec 19. doi: 10.1038/s41565-022-01261-7 Shi C, Zhang Q, Yao Y, Zeng F, Du C, Nijiati S, Wen X, Zhang X, Yang H, Chen H, Guo Z, Zhang X, Gao J, Guo W, Chen X, Zhou Z. Targeting the activity of T cells by membrane surface redox regulation for cancer theranostics. Nat Nanotechnol. 2022 Dec 19. doi: 10.1038/s41565-022-01261-7. Epub ahead of print. PMID: 36536041.
Evolution of drug regulations and regulatory innovation for anticancer drugs in China.Acta Pharm Sin B. 2022 Dec;12(12):4365-4377 Liu Y, Zhang N, Xie C, Jiang Y, Qin Y, Zhou L, Fan Y, Ren L, Yin C, Yang H, Xie W, Zhai Q, Li G, Chen H, Chen X.
Safety and efficacy of peptide receptor radionuclide therapy with 177Lu-DOTA-EB-TATE in patients with metastatic neuroendocrine tumors Theranostics 2022; 12(15):6437-6445.Jiang Y, Liu Q, Wang G, Sui H, Wang R, Wang J, Zhang J, Zhu Z, Chen X.
Organic phosphorescent nanoscintillator for low-dose X-ray-induced photodynamic therapy.Nat Commun. 2022;13(1):5091.Wang X, Sun W, Shi H, Ma H, Niu G, Li Y, Zhi J, Yao X, Song Z, Chen L, Li S, Yang G, Zhou Z, He Y, Qu S, Wu M, Zhao Z, Yin C, Lin C, Gao J, Li Q, Zhen X, Li L, Chen X, Liu X, An Z, Chen H, Huang W.
Targeting the activity of T cells by membrane surface redox regulation for cancer theranostics Nat Nanotechnol, in press.Shi C, Zhang Q, Zeng F, Du C, Nijiati S, Wen X, Yang H, Guo Z, Zhang X, Gao J, Chen X, Zhou Z
A pilot study of 68 Ga-PSMA-617 PET/CT imaging and 177Lu-EB-PSMA-617 radioligand therapy in patients with adenoid cystic carcinoma.EJNMMI Res. 2022 Aug 19;12(1):52.Wang G, Zhou M, Zang J, Jiang Y, Chen X, Zhu Z, Chen X.
Combined 18F-FDG and 18F-Alfatide II PET May Predict Luminal B (HER2 Negative) Subtype and Nonluminal Subtype of Invasive Breast Cancer.Mol Pharm. 2022 Aug 16. doi: 10.1021/acs.molpharmaceut.2c00547.Wu J, Zhang X, Jia Z, Zhou X, Qi R, Ji H, Sun J, Sun C, Teng Z, Lu G, Chen X.
Cancer Nanomedicine Nat Rev Cancer, doi: 10.1038/s41568-022-00496-9 Bhatia S, Chen X, Dobrovolskaia M, Lammers T
Management of fluorescent organic/inorganic nanohybrids for biomedical applications in the NIR-II region Chem Soc Rev, Li B, Zhao M, Lin J, Huang P, Chen X
Microfluidics-Assisted Fluorescence Mapping of DNA Phosphorothioation Anal Chem, 2022 Jul 26;94(29):10479-10486 Huang Q, Chen X, Meng Q-F, Yue L, Jiang W, Zhao X-Z, Rao L, Chen X, S chen
Harnessing Immune Response Using Reactive Oxygen Species-Generating/Eliminating Inorganic Biomaterials for Disease Treatment Adv Drug Deliv Rev, 2022 Jul 16;188:114456 Zhao C, Deng H, Chen X
Super-stable cyanine@albumin fluorophore for enhanced NIR-II bioimaging Theranostics. 2022 May 26;12(10):4536-4547 Bai L, Hu Z, Han T, Wang Y, Xu J, Jiang G, Feng X, Sun B, Liu X, Tian R, Sun H, Zhang S, Chen X, Zhu S.
Nanomaterial-Mediated Ablation Therapy for Cancer Stem Cells Matter, 2022;5: 1367-1390.Pan Y, Liu L, Rao L, Chen X
Chiral gold clusters functionalized two-dimensional nanoparticle films to regulate the adhesion and differentiation of stem cells J Colloid Interface Sci. 2022;625:831-838.Kang X, Wang Y, Cai XL, Hua Y, Shao ZH, Chen X, Zhao X, Zang SQ.
Cucurbituril-based Supramolecular Polymers for Biomedical ApplicationsAngew Chem Int Ed Engl. 2022 Jun 28. doi: 10.1002/anie.202206763.Wang Z, Sun C, Yang K, Chen X, Wang R.
The Roles of Polymers in mRNA Delivery Matter, 2022;5:1670-1699.Huang P, Deng H, Zhou Y, Chen X
Levonorgestrel-protected Au8 and Au10 clusters with different antimicrobial abilities J Mater Chem B. 2022 Jun 20. doi: 10.1039/d2tb00533f.Wang Y, Hua Y, Shao ZH, Chen X, Zhao X, Zang SQ.
Composition-Dependent Enzyme Mimicking Activity and Radiosensitizing Effect of Bimetallic Clusters to Modulate Tumor Hypoxia for Enhanced Cancer Therapy Adv Mater. 2022:e2203734.Hua Y, Huang JH, Shao ZH, Luo XM, Wang ZY, Liu JQ, Zhao X, Chen X, Zang SQ.
PD-L1-Targeted Radionuclide Therapy Combined with αPD-L1 Antibody Immunotherapy Synergistically Improves the Antitumor Effect Mol Pharm. 2022 Jun 2. doi: 10.1021/acs.molpharmaceut.2c00281.Wen X, Zeng X, Cheng X, Zeng X, Liu J, Zhang Y, Li Y, Chen H, Huang J, Guo Z, Chen X, Zhang X.
Rational Design and Pharmacomodulation of Protein-Binding Theranostic Radioligands for Targeting the Fibroblast Activation Protein J Med Chem. 2022 Jun 5. doi: 10.1021/acs.jmedchem.1c02162.Meng L, Fang J, Zhao L, Wang T, Yuan P, Zhao Z, Zhuang R, Lin Q, Chen H, Chen X, Zhang X, Guo Z.
A genetic engineering strategy for editing near-infrared-II fluorophores.Nat Commun. 2022 May 23;13(1):2853.Tian R, Feng X, Wei L, Dai D, Ma Y, Pan H, Ge S, Bai L, Ke C, Liu Y, Lang L, Zhu S, Sun H, Yu Y, Chen X.
Protective Effect of Platinum Nano-antioxidant and Nitric Oxide Against Hepatic Ischemia-Reperfusion Injury Nat Commun, 2022;13(1):2513 Mu J, Li C, Shi Y, Liu G, Zou J, Zhang D, Jiang C, Wang X, He L, Huang P, Yin Y, Chen X
Reactive Oxygen Species Scavenging Nanomedicine for The Treatment of Ischemic Heart Disease Adv Mater. 2022:e2202169.Zhang Z, Dalan R, Hu Z, Wang JW, Chew NW, Poh KK, Tan RS, Soong TW, Dai Y, Ye L, Chen X.
Photoacoustic Imaging-Guided Synergistic Photothermal/Radiotherapy Using Plasmonic Bi/Bi2O3-x Nanoparticles Adv Funct Mater,Huang X, Zha F, Zou J, Li Y, Wang F, Chen X
Smart Mushroom-Inspired Imprintable and Lightly Detachable (MILD) Microneedle Patterns for Effective COVID-19 Vaccination and Decentralized Information Storage ACS Nano. 2022 Apr 22. doi: 10.1021/acsnano.1c10718.Li Q, Xu R, Fan H, Xu J, Xu Y, Cao P, Zhang Y, Liang T, Zhang Y, Chen W, Wang Z, Wang L, Chen X
A nanovaccine for antigen self-presentation and immunosuppression reversal as a personalized cancer immunotherapy strategy Nat Nanotechnol. 2022 Apr 11. doi: 10.1038/s41565-022-01098-0.Liu C, Liu X, Xiang X, Pang X, Chen S, Zhang Y, Ren E, Zhang L, Liu X, Lv P, Wang X, Luo W, Xia N, Chen X, Liu G
Avoiding the self-nucleation interference: a pH-regulated gold in situ growth strategy to enable ultrasensitive immunochromatographic diagnostics Theranostics. 2022;12(6):2801-2810.Duan H, Ma T, Huang X, Gao B, Zheng L, Chen X, Xiong Y, Chen X
Combined Probe Strategy to Increase the Enzymatic Digestion Rate and Accelerate the Renal Radioactivity Clearance of Peptide Radiotracers Mol Pharm. 2022 Mar 31. doi: 10.1021/acs.molpharmaceut.2c00051.Zhang M, Ye J, Xie Z, Wang Y, Ma W, Kang F, Yang W, Wang J, Chen X
A paradigm of cancer immunotherapy based on 2-[18F]FDG and anti-PD-L1 mAb combination to enhance the anti-tumor effect Clin Cancer Res. 2022 Mar 23:clincanres.0159.2022.Wen X, Shi C, Zeng X, Zhao L, Yao L, Liu Z, Feng L, Zhang D, Huang J, Li Y, Lin Q, Chen H, Zhuang R, Chen X, Zhang X, Guo Z.
Preliminary Clinical Application of RGD-Containing Peptides as PET Radiotracers for Imaging Tumors Front Oncol. 2022;12:837952.Li L, Chen X, Yu J, Yuan S.
A tumor microenvironment dual responsive contrast agent for contrary contrast-magnetic resonance imaging and specific chemotherapy of tumors Nanoscale Horiz. 2022 Feb 25. doi: 10.1039/d1nh00632k.Lu Y, Feng J, Liang Z, Lu X, Guo S, Huang L, Xiong W, Chen S, Zhou H, Ma X, Xu Y, Qiu X, Wu A, Chen X, Shen Z.
A super-stable homogeneous Lipiodol-hydrophilic chemodrug formulation for treatment of hepatocellular carcinoma Theranostics. 2022;12(4):1769-1782.He P, Ren E, Chen B, Chen H, Cheng H, Gao X, Liang X, Liu H, Li J, Li B, Chen A, Chu C, Chen X, Mao J, Zhang Y, Liu G.
Recent advances in biomaterial-boosted adoptive cell therapy Chem Soc Rev. 2022 Feb 16. doi: 10.1039/d1cs00786f.Xue Y, Che J, Ji X, Li Y, Xie J, Chen X.
A "Self-Checking" pH/Viscosity-Activatable NIR-II Molecule for Real-Time Evaluation of Photothermal Therapy Efficacy Angew Chem Int Ed Engl. 2022 Feb 15. doi: 10.1002/anie.202200025.Li B, Liu H, He Y, Zhao M, Ge C, Younis MR, Huang P, Chen X, Lin J.
Antibody-Incorporated Nanomedicines for Cancer Therapy Adv Mater. 2022 Feb 10:e2109210. doi: 10.1002/adma.202109210.Wu SY, Wu FG, Chen X.
18F-Alfatide II for the evaluation of axillary lymph nodes in breast cancer patients: comparison with 18F-FDG Eur J Nucl Med Mol Imaging. 2022 Feb 9. doi: 10.1007/s00259-021-05333-z.Wu J, Tian J, Zhang Y, Ji H, Sun J, Wang X, Sun C, Wang L, Teng Z, Lu G, Zhu H, Chen X.
Noninvasive Dual-Modality Photoacoustic-Ultrasonic Imaging to Detect Mammalian Embryo Abnormalities after Prenatal Exposure to Methylmercury Chloride (MMC): A Mouse Study Environ Health Perspect. 2022;130(2):27002.Qiu Q, Huang Y, Zhang B, Huang D, Chen X, Fan Z, Lin J, Yang W, Wang K, Qu N, Li J, Li Z, Huang J, Li S, Zhang J, Liu G, Rui G, Chen X, Zhao Q
Hybrid Membrane-Decorated Prussian Blue for Effective Cancer Immunotherapy via Tumor-Associated Macrophages Polarization and Hypoxia Relief Adv Mater. 2022 Feb 1:e2200389.Hou L, Gongu X, Zhang JH, Yang W, Chen X
Metal-free bioorthogonal click chemistry in cancer theranostics Chem Soc Rev. 2022 Jan 20. doi: 10.1039/d1cs00451d.Wu D, Yang K, Zhang Z, Feng Y, Rao L, Chen X, Yu G.
Evans blue-modified radiolabeled fibroblast activation protein inhibitor as long-acting cancer therapeutics Theranostics. 2022;12(1):422-433.Wen X, Xu P, Shi M, Liu J, Zeng X, Zhang Y, Shi C, Li J, Guo Z, Zhang X, Khong PL, Chen X.
Near-infrared probes for luminescence lifetime imaging Nanotheranostics. 2022;6(1):91-102.Li B, Lin J, Huang P, Chen X.
Coordinating the mechanism of actions of ferroptosis and photothermal effect for cancer theranostics Angew Chem Int Ed Engl. 2021 Dec 21. doi: 10.1002/anie.202112925.Zeng F, Tang L, Zhang Q, Shi C, Huang Z, Nijiati S, Chen X, Zhou Z.
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Combined 68Ga-NOTA-Evans Blue Lymphoscintigraphy and 68Ga-NOTA-RM26 PET/CT Evaluation of Sentinel Lymph Node Metastasis in Breast Cancer Patients Bioconjug Chem, 2020; 31(2):396-403.Zang J, Liu Q, Sui H, Guo H, Peng L, Li F, Lang L, Jacobson O, Mao F, Zhu Z, Chen X
Smart Nanovesicle Mediated Immunogenic Cell Death Through Tumor Microenvironment Modulation for Effective Photodynamic-Immunotherapy ACS Nano, 2020;14(1):620-631 Yang W, Zhang F, Deng H, Lin L, Wang S, Kang F, Yu G, Lau J, Tian R, Zhang M, Wang Z, He L, Ma Y, Niu G, Hu S, Chen X
Label-free Visualization of Early Cancer Hepatic Micrometastasis and Intraoperative Image-guided Surgery by Photoacoustic Imaging J Nucl Med. 2020;61(7):1079-1085.Yu Q, Huang S, Wu Z, Zheng J, Chen X, Nie L.
A bi-adjuvant nanovaccine that potentiates immunogenicity of neoantigen for combination immunotherapy of colorectal cancer Sci Adv, 2020;6:eaaw6071 Ni Q, Zhang F, Liu Y, Wang Z, Yu G, Liang B, Niu G, Su T, Lu G, Zhu G, Zhang L, Chen X
Ultrasound Activated Vesicle of Janus Au-MnO Nanoparticles for Promoted Tumor Penetration and Sono-Chemodynamic Therapy of Orthotopic Liver Cancer Angew Chem Int Ed Engl. 2020;59(4):1682-1688.Lin X, Liu S, Zhang X, Zhu R, Chen S, Chen X, Song J, Yang H.
Nanoscintillator-mediated X-ray induced photodynamic therapy for deep-seated tumors: from concept to biomedical applications Theranostics, 2020;10(3):1296-1318. Sun W, Zhou Z, Pratx G, Chen X, Chen H
Core–Shell Heterostructured Magnetic–Plasmonic Nanoassemblies with Highly Retained Magnetic–Plasmonic Activities for Ultrasensitive Bioanalysis in Complex Matrix Adv Sci, 2020;7:1902433 Hao L, Leng Y, Zeng L, Chen X, Chen J, Duan H, Huang X, Xiong Y, Chen X
Supramolecular Recognition-Mediated Layer-by-Layer Self-Assembled Gold Nanoparticles for Customized Sensitivity in Paper-Based Strip Nanobiosensors Small. 2019;15(51):1903861.Huang X, Zhou Y, Ding L, Yu G, Leng Y, Lai W, Xiong Y, Chen X
DOTA-Branched Organic Frameworks as Giant and Potent Metal Chelators J Am Chem Soc. 2020;142(1):198-206.Sun C, Lin H, Gong X, Yang Z, Mo Y, Chen X, Gao J.
Tale of Two Magnets: A New Design of Magnetic Targeting System ACS Nano, 2020;14(1):7-11 Zhou Z, Shen Z, Chen X
Dose Escalation of an Evans Blue Modified Radiolabeled Somatostatin Analogue 177Lu-DOTA-EBTATE in the Treatment of Metastatic Neuroendocrine Tumors Eur J Nucl Med Mol Imaging. 2020;47(4):947-957 Liu Q, Cheng Y, Zang J, Sui Hm Wang H, Jacobson O, Zhu Z, Chen X
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