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Porous Co3O4 nanosheets as a high-performance non-enzymatic sensor for glucose detection

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Abstract

Novel porous Co3O4 nanosheets (NSs) were synthesized on the flexible carbon cloth (CC) substrate by a facile hydrothermal method and applied to construct a non-enzymatic sensor for glucose detection. The sensor is based on the electro-catalytic oxidation of glucose on the surface of Co3O4 NSs. Since this particular nanostructure can provide large surface area and more active sites, the Co3O4 NSs non-enzymatic sensor exhibits excellent analytical performance, such as a high sensitivity (8506 μA mM−1 cm−2), a fast response time (less than 6 s), low detection limit of 1 μM, good selectivity, and long-term stability. The results suggest that the porous Co3O4 NSs have great potential applications in the development of sensors for enzyme-free detection of glucose.

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Funding

This work was financially supported by the National Natural Science Foundation of China (No. 51602179, 21333006, 21573135, 11374190, and 21675104), the National Basic Research Program of China (973 Program, No. 2013CB632401), Recruitment Program for Young Professionals and China and Taishan Scholar Foundation of Shandong Province, China.

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Authors and Affiliations

  1. State Key Lab of Crystal Materials, Shandong University, Jinan, 250100, Shandong, China

    Fuyan Liu, Peng Wang, Qianqian Zhang, Zeyan Wang, Yuanyuan Liu, Zhaoke Zheng, Xiaoyan Qin, Xiaoyang Zhang & Baibiao Huang

  2. School of Physics, Shandong University, Jinan, 250100, Shandong, China

    Ying Dai

  3. College of Chemistry, Chemical Engineering and Materials Science, Key Laboratory of Molecular and Nano Probes, Ministry of Education, Collaborative Innovation Center of Functionalized Probes for Chemical Imaging, Shandong Normal University, Jinan, 250014, Shandong, China

    Lu Li

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  1. Fuyan Liu
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  2. Peng Wang
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  10. Lu Li
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Correspondence to Peng Wang or Baibiao Huang.

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Liu, F., Wang, P., Zhang, Q. et al. Porous Co3O4 nanosheets as a high-performance non-enzymatic sensor for glucose detection. Anal Bioanal Chem 410, 7663–7670 (2018). https://doi.org/10.1007/s00216-018-1380-4

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  • DOI: https://doi.org/10.1007/s00216-018-1380-4

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