Using clear cell renal cell carcinoma (ccRCC) subtypes (ccrcc1–4) to classify patients with metastatic ccRCC who have undergone complete metastasectomy can improve prediction of early relapse, say researchers. In their study involving 43 patients with ccRCC, Verbiest et al. found that median disease-free survival after complete metastasectomy was longer in patients with ccrcc2 or ccrcc3 tumours than in those with ccrcc1 or ccrcc4 tumours (23 months versus 9 months).
References
Verbiest, A. et al. Molecular subtypes of clear-cell renal cell carcinoma are prognostic for outcome after complete metastasectomy. Eur. Urol. https://doi.org/10.1016/j.eururo.2018.01.042 (2018)
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Kelsey, R. ccrcc1–4 classification for prediction of relapse. Nat Rev Urol 15, 205 (2018). https://doi.org/10.1038/nrurol.2018.34
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DOI: https://doi.org/10.1038/nrurol.2018.34