Issue 11, 2017

Divergent synthesis of hydropyridine derivatives via nitrogen-containing Lewis base mediated regioselective [4 + 2] cyclizations

Abstract

A nitrogen-containing Lewis base mediated regioselective [4 + 2] cyclization strategy between allenic esters and α,β-unsaturated ketimines was discovered, affording a series of hydropyridine derivatives in moderate to good yields under mild conditions.

Graphical abstract: Divergent synthesis of hydropyridine derivatives via nitrogen-containing Lewis base mediated regioselective [4 + 2] cyclizations

Supplementary files

Article information

Article type
Research Article
Submitted
18 Jul 2017
Accepted
16 Aug 2017
First published
16 Aug 2017

Org. Chem. Front., 2017,4, 2216-2220

Divergent synthesis of hydropyridine derivatives via nitrogen-containing Lewis base mediated regioselective [4 + 2] cyclizations

H. Jin, E. Li and Y. Huang, Org. Chem. Front., 2017, 4, 2216 DOI: 10.1039/C7QO00596B

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