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Long-lived plasma cells

Tissues of origin matter to plasma cell longevity

Nature Immunology volume 25, pages 194–195 (2024)Cite this article

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Anatomical separation exists between the generation and lodging sites of plasma cells. Transcriptome analysis of tissue-resident plasma cells provides important insights into how newly generated plasma cells acquire longevity.

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Fig. 1: Generation of tissue-resident long-lived plasma cells.

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Authors and Affiliations

  1. Regulation of Host Defense Team, Division of Microbiology and Immunology, Center for Infectious Disease Education and Research, Osaka University, Osaka, Japan

    Wataru Ise

  2. Laboratory of Lymphocyte Differentiation, WPI Immunology Frontier Research Center, Osaka University, Osaka, Japan

    Tomohiro Kurosaki

  3. Division of Microbiology and Immunology, Center for Infectious Disease Education and Research, Osaka University, Osaka, Japan

    Tomohiro Kurosaki

  4. Laboratory for Lymphocyte Differentiation, RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa, Japan

    Tomohiro Kurosaki

Authors
  1. Wataru Ise
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  2. Tomohiro Kurosaki
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Correspondence to Wataru Ise or Tomohiro Kurosaki.

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The authors declare no competing interests.

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Ise, W., Kurosaki, T. Tissues of origin matter to plasma cell longevity. Nat Immunol 25, 194–195 (2024). https://doi.org/10.1038/s41590-023-01731-7

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