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Low-Triggering-Potential and Narrow-Potential-Window Electrochemiluminescence of Silver Nanoclusters for Gene Assay Anal. Chem. (IF 7.4) Pub Date : 2024-04-17 Yaojia Ai, Xuwen Gao, Xiaoxuan Ren, Mengwei Li, Bin Zhang, Guizheng Zou
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Furin-Catalyzed Enhanced Magnetic Resonance Imaging Probe for Differential Diagnosis of Malignant Breast Cancers Anal. Chem. (IF 7.4) Pub Date : 2024-04-17 Weiwei Zeng, Zhuoyao Wu, Yan Xu, Weitao Yang, Bingbo Zhang
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Interlaboratory Comparison on Absolute Photoluminescence Quantum Yield Measurements of Solid Light Converting Phosphors with Three Commercial Integrating Sphere Setups Anal. Chem. (IF 7.4) Pub Date : 2024-04-17 Saskia Fiedler, Florian Frenzel, Christian Würth, Isabella Tavernaro, Michelle Grüne, Stefan Schweizer, Axel Engel, Ute Resch-Genger
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Label-Free Multiplex Profiling of Exosomal Proteins with a Deep Learning-Driven 3D Surround-Enhancing SERS Platform for Early Cancer Diagnosis Anal. Chem. (IF 7.4) Pub Date : 2024-04-16 Miao Chen, Haoyang Wang, Yibin Zhang, Hanyu Jiang, Tan Li, Lixin Liu, Yuetao Zhao
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Anisotropic Elastomer Ionomer Composite-Based Strain Sensors: Achieving High Sensitivity and Wide Detection for Human Motion Detection and Wireless Transmission ACS Sens. (IF 8.9) Pub Date : 2024-04-17 Jiawen Dai, Dong Liu, Xianze Yin, Xianjie Wen, Guangming Cai, Long Zheng
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Selective Sparse Sampling of Water Droplets in Oil with Acoustic Tweezers ACS Sens. (IF 8.9) Pub Date : 2024-04-16 Siying Lin, Antoine Riaud, Jia Zhou
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Development of a microfluidic device to enrich and detect zearalenone in food using quantum dot-embedded molecularly imprinted polymers Lab Chip (IF 6.1) Pub Date : 2024-04-17 Marti Hua, Shenmiao Li, Roopesh Syamaladevi, Xiaonan Lu
Mycotoxins are secondary metabolites of certain moulds, prevalent in 60-80% of food crops and many processed products but challenging to eliminate. Consuming mycotoxin-contaminated food and feed can lead to various adverse effects on humans and livestock. Therefore, testing mycotoxin residue levels is critical to ensure food safety. Gold standard analytical methods rely on liquid chromatography coupled
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Rocking- and diffusion-based culture of tumor spheroids-on-a-chip Lab Chip (IF 6.1) Pub Date : 2024-04-15 Duomei Tian, Zheng Mao, Li Wang, Xiaochen Huang, Wei Wang, Haoyue Luo, Juan Peng, Yong Chen
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Prediction of mass spectrometry ionization efficiency based on COSMO-RS and machine learning algorithms Analyst (IF 4.2) Pub Date : 2024-04-17 Cheng-Zhen Nie, Hao Liu, Xu-Hui Huang, Da-Yong Zhou, Xu-Song Wang, Lei Qin
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Potential and Performance of Anisotropic 19F NMR for the Enantiomeric Analysis of Fluorinated Chiral Active Pharmaceutical Ingredients Analyst (IF 4.2) Pub Date : 2024-04-17 Boris Gouilleux, Francois-Marie. Moussallieh, Philippe Lesot
Controlling the enantiomeric purity of chiral drugs is of paramount importance in pharmaceutical chemistry. Isotropic 1H NMR spectroscopy involving chiral agents is a widely used method for discriminating enantiomers and quantifying their relative proportions. However, the relatively weak spectral separation of enantiomers (1H Δδiso(R,S)) in frequency units at low and moderate magnetic fields, as well
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Development of a Novel X-ray Fluorescence Instrument Equipped with a Noble Gas Filter Analyst (IF 4.2) Pub Date : 2024-04-17 Tsugufumi Matsuyama, Tomoya Miyahara, Hiroshi Yoshii, Lim Lee Wha, Kouichi Tsuji
In X-ray fluorescence (XRF) analysis, which has been used to analyze elements in various samples, it is important to decrease the background (BG) intensity. Generally, BG signals are reduced by inserting metal foils of various types and thicknesses between the X-ray tube and sample as primary X-ray filters. In this study, we developed a unique gas filter-XRF (GF-XRF) instrument to easily reduce the
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Construction of novel NIR fluorescent Nile Blue@MOF nanoprobe for imaging mitochondrial ATP in living cells Analyst (IF 4.2) Pub Date : 2024-04-17 Yifan Zhao, Xinfeng Cheng, Minglin Lei, Luyi Zong, Xianchao Du, Mengying Gao, Xueguo Liu, Dongfang Qiu, Xiaojing Xing
A novel near-infrared (NIR) fluorescent nanoprobe consisting of Nile Blue (NB)-capped ZIF-90 (NB@ZIF-90) is first proposed for real-time imaging mitochondrial ATP. Upon the addition of ATP, the structure of NB@ZIF-90 is disrupted owing to the strong binding affinity of ATP with Zn2+, resulting in the release of NB and the generation of strong NIR fluorescence.
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Impact electrochemistry for biosensing: advances and future directions Analyst (IF 4.2) Pub Date : 2024-04-15 Jian-Hua Zhang, Dian-Mei Song, Yi-Ge Zhou
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Codetection of Proteins and RNAs on Extracellular Vesicles for Pancreatic Cancer Early Diagnosis Anal. Chem. (IF 7.4) Pub Date : 2024-04-16 Jie He, Jiang Long, Chunhui Zhai, Jiasu Xu, Kaiwen Bao, Wenqiong Su, Lai Jiang, Guangxia Shen, Xianting Ding
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A Portable Nucleic Acid Testing Platform with Photosensitization, a Three-Dimensionally Printed Multipiece Chip, and Digital Color Sensing Anal. Chem. (IF 7.4) Pub Date : 2024-04-16 Tianyu Dong, Ruolin Ding, Rongxing Zhou, Chenlan Shen, Will Sheridan, Dixon Paez, Zhihe Zhao, Peng Wu, Feng Li
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Visualization of Modified Bisarylbutadiyne-Tagged Small Molecules in Live-Cell Nuclei by Stimulated Raman Scattering Microscopy Anal. Chem. (IF 7.4) Pub Date : 2024-04-16 Makoto Kawaguchi, Yuki Yonetani, Takaha Mizuguchi, Spencer J. Spratt, Masato Asanuma, Hiroki Shimizu, Masato Sasaki, Yasuyuki Ozeki
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Improved Mass Accuracy and Precision for Multiattribute Methods Using a New Internally Calibrated High Resolution Orbitrap Mass Detector Anal. Chem. (IF 7.4) Pub Date : 2024-04-16 Andrew W. Dawdy, Edna A. Trujillo, Zhenjiu Liu, Catharina Crone, Julia Kraegenbring, Kai Scheffler
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Fast-Response and Low-Power Self-Heating Gas Sensor Using Metal/Metal Oxide/Metal (MMOM) Structured Nanowires ACS Sens. (IF 8.9) Pub Date : 2024-04-16 Min-Seung Jo, Sung-Ho Kim, So-Yoon Park, Kwang-Wook Choi, Sang-Hee Kim, Jae-Young Yoo, Beom-Jun Kim, Jun-Bo Yoon
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Plasmonic Imaging of Single DNA with Charge Sensitive Monolayer WS2 ACS Sens. (IF 8.9) Pub Date : 2024-04-16 Yang Liu, Shuangshuang Gao, Lixuan Liu, Ji Wang, Dapeng Wang, Jianyong Xiang, Anmin Nie, Kun Zhai, Congpu Mu, Fusheng Wen, Bochong Wang, Tianyu Xue, Zhongyuan Liu
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Multiplex nanozymatic biosensing of Salmonella on a finger-actuated microfluidic chip Lab Chip (IF 6.1) Pub Date : 2024-04-16 Nana Jin, Fan Jiang, Fengzhen Yang, Ying Ding, Ming Liao, Yanbin Li, Jianhan Lin
A colorimetric biosensor was elaboratively designed for fast, sensitive and multiplex bacterial detection on a single microfluidic chip using immune magnetic nanobeads for specific bacterial separation, immune gold@platinum palladium nanoparticles for specific bacterial labeling, a finger-actuated mixer for efficient immunoreaction and two coaxial rotatable magnetic fields for magnetic nanobead capture
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Assessment of urine sample collection and processing variables for extracellular vesicle-based proteomics Analyst (IF 4.2) Pub Date : 2024-04-16 Guiyuan Zhang, Yajie Ding, Hao Zhang, Dong Wei, Yufeng Liu, Jie Sun, Zhuoying Xie, Andy Tao, Yufei Zhu
Extracellular vesicles (EVs) in urine are a promising source to develop non-invasive biomarkers. However, urine concentration and content are highly variable and dynamic, and actual urine collection and handling often is nonideal. Furthermore, patients such as those with prostate diseases have challenges in sample collection due to difficulties in holding urine at designated time points. Here, we simulated
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Advances in uremic toxin detection and monitoring in the management of chronic kidney disease progression to end-stage renal disease Analyst (IF 4.2) Pub Date : 2024-04-16 Han Lee, Kuan-Hung Liu, Yu-Hsuan Yang, Jiunn-Der Liao, Bo-shen Lin, Zheng-Zhe Wu, Alice Chang, Chin-Chung Tseng, Ming-Cheng Wang, Yau-Sheng Tsai
Patients with end-stage kidney disease (ESKD) rely on dialysis to remove toxins and stay alive. However, hemodialysis alone is insufficient to completely remove all/major uremic toxins, resulting in the accumulation of specific toxins over time. The complexity of uremic toxins and their varying clearance rates across different dialysis modalities poses significant challenges, and innovative approaches
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A Mitochondria-Targeted Nitric Oxide Probe for Multimodality Imaging of Macrophage Immune Responses Anal. Chem. (IF 7.4) Pub Date : 2024-04-16 Yuxin Wen, Xianbo Wu, Weijun Wu, Tao Feng, Yihang Pan, Yulong He, Liangnian Ji, Hui Chao
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Rapid Detection of Broad-Spectrum Pathogenic Bacteria Based on Highly Sensitive Proton Response of the Nucleic Acid Amplification SPQC Platform Anal. Chem. (IF 7.4) Pub Date : 2024-04-16 Yusheng Liao, Yu Liu, Ye Feng, Deshuai Zhen, Fengjiao He
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Fast Detection and Classification of Microplastics below 10 μm Using CNN with Raman Spectroscopy Anal. Chem. (IF 7.4) Pub Date : 2024-04-16 Jeonghyun Lim, Gogyun Shin, Dongha Shin
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Innovative Approaches for Drug Discovery: Quantifying Drug Distribution and Response with Raman Imaging Anal. Chem. (IF 7.4) Pub Date : 2024-04-16 Erin L. Dunnington, Brian S. Wong, Dan Fu
This article has not yet been cited by other publications.
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Multicolor-Assay-on-a-Chip Processed by Robotic Operation (MACpro) with Improved Diagnostic Accuracy for Field-Deployable Detection Anal. Chem. (IF 7.4) Pub Date : 2024-04-15 Binyao Liu, Yixin Cheng, Xiang Pan, Wen Yang, Xiangpeng Li, Lele Wang, Haihang Ye, Tingrui Pan
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Amplified Biosensors Powered by Endogenous Molecules for Intracellular Fluorescence Imaging Anal. Chem. (IF 7.4) Pub Date : 2024-04-15 Yibo Zhou, Jun Zhang, Shuanghong Sun, Weiju Chen, Yuping Wang, Huiqiu Shi, Ronghua Yang, Zhihe Qing
This article has not yet been cited by other publications.
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Speckle Variance Photoacoustic Microscopy for Microhemodynamic Imaging ACS Sens. (IF 8.9) Pub Date : 2024-04-16 Wei Song, Yiyan Zhuang, Yifan Yang, Deyan Xie, Changjun Min, Xiaocong Yuan
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FO-SPR Model for Full-Spectrum Signal Analysis of Back-reflecting FO-SPR Sensors to Monitor MOF Deposition ACS Sens. (IF 8.9) Pub Date : 2024-04-15 Wouter Vandezande, Annelies Dillen, Jeroen Lammertyn, Maarten B. J. Roeffaers
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A compact and high-performance setup of capillary electrophoresis with capacitively coupled contactless conductivity detection (CE-C4D) Analyst (IF 4.2) Pub Date : 2024-04-16 Lin Li, Yun-Peng Song, Dou-Dou Ren, Tang-Xiu Li, Ming-Hui Gao, Lei Zhou, Zhi-Cong Zeng, Qi-aosheng Pu
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Native Mass Spectrometry of Complexes Formed by Molecular Glues Reveals Stoichiometric Rearrangement of E3 Ligases Analyst (IF 4.2) Pub Date : 2024-04-16 Cara Jackson, Rebecca Beveridge
In this application of native mass spectrometry (nMS) to investigate complexes formed by molecular glues (MGs), we have demonstrated its efficiency in delineating stoichiometric rearrangements of E3 ligases that occur during targeted protein degradation (TPD). MGs stabilise interactions between an E3 ligase and a protein of interest (POI) targeted for degradation, and these ternary interactions are
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Photonic–plasmonic resonator for SERS biodetection Analyst (IF 4.2) Pub Date : 2024-04-13 Zheng Tian, Zhonghai Zhang
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Copper(II) phthalocyanine as an electrocatalytic electrode for cathodic detection of urinary tryptophan Analyst (IF 4.2) Pub Date : 2024-04-12 Pachanuporn Sunon, Busarakham Ngokpho, Keerakit Kaewket, Suttipong Wannapaiboon, Kamonwad Ngamchuea
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Quantitative Real-Time Analysis of Living Materials by Stimulated Raman Scattering Microscopy Anal. Chem. (IF 7.4) Pub Date : 2024-04-15 Chenxi Qian, Hanwei Liu, Priya K. Chittur, Rahuljeet S. Chadha, Yuxing Yao, Julia A. Kornfield, David A. Tirrell, Lu Wei
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Two-Dimensional Fourier Transform Ion Cyclotron Resonance Mass Spectrometry by Matrix-Assisted Laser Desorption Ionization Anal. Chem. (IF 7.4) Pub Date : 2024-04-15 Richard J. Bell, David S. Hage, Eric D. Dodds
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Spot-Based Global Registration for Subpixel Stitching of Single-Molecule Resolution Images for Tissue-Scale Spatial Transcriptomics Anal. Chem. (IF 7.4) Pub Date : 2024-04-15 Seokjin Yeo, Alex W. Schrader, Juyeon Lee, Marisa Asadian, Hee-Sun Han
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Stretchable Photonic Crystal-Assisted Glycoprotein Identification for Ovarian Cancer Diagnosis Anal. Chem. (IF 7.4) Pub Date : 2024-04-15 Xinyi Jian, Fei Chen, Wei Wei, Xiaoyu Zhang, Nan Cheng, Jundong Li, Fengyu Li
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High-Density Microporous Drainage-Integrating Sheath Flow Generator for Streamlining Microfluidic Cell Sorting Systems Anal. Chem. (IF 7.4) Pub Date : 2024-04-15 Ayumi Hayashi, Runa Hemmi, Yuhei Saito, Rie Utoh, Tatsuo Taniguchi, Masumi Yamada
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AptaShield: A Universal Signal-Transduction System for Fast and High-Throughput Optical Molecular Biosensing ACS Sens. (IF 8.9) Pub Date : 2024-04-15 Miguel António Dias Neves, Inês Mendes Pinto
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Proximity-Guaranteed DNA Machine for Accurate Identification of Breast Cancer Extracellular Vesicles ACS Sens. (IF 8.9) Pub Date : 2024-04-15 Shuang Yang, Liang Zhou, Zhikai Fang, Ying Wang, Guozhang Zhou, Xi Jin, Ya Cao, Jing Zhao
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Resistive Pulse Analysis of Chiral Amino Acids Utilizing Metal-Amino Acid Crystallization Differences Analyst (IF 4.2) Pub Date : 2024-04-15 Blake Stringer, Alexandra Schmeltzer, C. Hyun Ryu, Hang Ren, Long Luo
Here, we report a proof-of-concept resistive pulse method for analyzing chiral amino acids utilizing metal-amino acid crystallization differences. This method involves introducing an amino acid sample solution into a micropipette through a pressure-driven flow. The sample then mixes with a metal ion solution inside the pipette, forming metal-amino acid crystals. The crystal size depends on the enantiomeric
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Metabolic profiling of murine radiation-induced lung injury with Raman spectroscopy and comparative machine learning Analyst (IF 4.2) Pub Date : 2024-04-10 Mitchell Wiebe, Kirsty Milligan, Joan Brewer, Alejandra M. Fuentes, Ramie Ali-Adeeb, Alexandre G. Brolo, Julian J. Lum, Jeffrey L. Andrews, Christina Haston, Andrew Jirasek
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Machine-Learning-Assisted Aggregation-Induced Emissive Nanosilicon-Based Sensor Array for Point-of-Care Identification of Multiple Foodborne Pathogens Anal. Chem. (IF 7.4) Pub Date : 2024-04-15 Yuechun Li, Zhaowen Cui, Ziqi Wang, Longhua Shi, Junchen Zhuo, Shengxue Yan, Yanwei Ji, Yanru Wang, Daohong Zhang, Jianlong Wang
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Efficient Electrochemical Microsensor for the Simultaneous Measurement of Hydrogen Peroxide and Ascorbic Acid in Living Brains Anal. Chem. (IF 7.4) Pub Date : 2024-04-15 Qiuyue Chen, Ruizhi Lin, Wenhui Wang, Yimei Zuo, Yi Zhuo, Yanyan Yu, Shu Chen, Hui Gu
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Isolation of Human Milk Difucosyl Nona- and Decasaccharides by Ultrahigh-Temperature Preparative PGC-HPLC and Identification of Novel Difucosylated Heptaose and Octaose Backbones by Negative-Ion ESI-MSn Anal. Chem. (IF 7.4) Pub Date : 2024-04-14 Cuiyan Cao, Yiming Cheng, Yi Zheng, Beibei Huang, Zhimou Guo, Long Yu, Barbara Mulloy, Virginia Tajadura-Ortega, Wengang Chai, Jingyu Yan, Xinmiao Liang
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Modeling Nonlinear Dynamics of Functionalization Layers: Enhancing Gas Sensor Sensitivity for Piezoelectrically Driven Microcantilever ACS Sens. (IF 8.9) Pub Date : 2024-04-15 Lawrence Nsubuga, Lars Duggen, Frank Balzer, Simon Høegh, Tatiana L. Marcondes, William Greenbank, Horst-Günter Rubahn, Roana de Oliveira Hansen
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Portable platform for leukocyte extraction from blood using sheath-free microfluidic DLD Lab Chip (IF 6.1) Pub Date : 2024-04-15 Oriana Gerallin Chavez-Pineda, Roberto Rodriguez-Moncayo, Alan Mauricio Gonzalez-Suarez, Pablo Enrique Guevara-Pantoja, Jose Luis Maravillas-Montero, Jose L. Garcia-Cordero
Leukocyte count is routinely performed for diagnostic purposes and is rapidly emerging as a significant biomarker for a wide array of diseases. Additionally, leukocytes have demonstrated considerable promise in novel cell-based immunotherapies. However, the direct retrieval of leukocytes from whole blood is a significant challenge due to their low abundance compared to erythrocytes. Here, we introduce
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High-Throughput μPAD with Cascade Signal Amplification through Dual Enzymes for arsM in Paddy Soil Anal. Chem. (IF 7.4) Pub Date : 2024-04-13 Haorui Cao, Kang Mao, Jiajia Yang, Qingqing Wu, Jiming Hu, Hua Zhang
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A Macrophage Membrane-Coated Cu–WO3–x-Hydro820 Nanoreactor for Treatment and Photoacoustic/Fluorescence Dual-Mode Imaging of Inflamed Liver Tissue Anal. Chem. (IF 7.4) Pub Date : 2024-04-13 Yanni Luo, Caiying Li, Fanggui Ye, Jianniao Tian, Xuecai Tan, Shengqiang Hu, Shulin Zhao
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Multienzyme-Mediated Dual-Channel Magnetic Relaxation Switching Taste Biosensor (D-MRSTB) for Simultaneous Detection of Umami Compounds and Synergistic Enhancement in Food ACS Sens. (IF 8.9) Pub Date : 2024-04-11 Liqin Kong, Yongzhen Dong, Guoqiang Shu, Yaoze Feng, Ming Zhu
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Isolation of acute myeloid leukemia blasts from blood using a microfluidic device Analyst (IF 4.2) Pub Date : 2024-04-13 Alexandra Teixeira, Maria Sousa-Silva, Alexandre Chicharo, Kevin Oliveira, André Távora Moura, Adriana Carneiro, Paulina Piairo, Hugo Águas, Belém Sampaio-Marques, José Mariz, Paula Ludovico, Sara Abalde-Cela, Lorena Diéguez, Isabel Castro
Acute myeloid leukemia (AML) is the most common form of acute leukemia in adults and associated with poor prognosis. Unfortunately, most of the patients that achieve clinical complete remission after the treatment will ultimately relapse due to the persistence of minimal residual disease (MRD), that is not measurable using conventional technologies in the clinic. Microfluidics is a potential tool to
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Artificial Intelligence-Assisted Multiparameter Size Discrimination of Silver Nanoparticles through Electrochemical Collision Anal. Chem. (IF 7.4) Pub Date : 2024-04-12 Ying Xu, Wei-Jian Jiang, Yi-Yan Bai, Yan-Ju Yang, Zhi-Ling Zhang
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Structural Characterization of a Pathogenic Antibody Underlying Vaccine-Induced Immune Thrombotic Thrombocytopenia (VITT) Anal. Chem. (IF 7.4) Pub Date : 2024-04-12 Son N. Nguyen, Si-Hung Le, Daniil G. Ivanov, Nikola Ivetic, Ishac Nazy, Igor A. Kaltashov
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In-Membrane Enrichment and Peptic Digestion to Facilitate Analysis of Monoclonal Antibody Glycosylation Anal. Chem. (IF 7.4) Pub Date : 2024-04-12 Junyan Yang, Raluca Ostafe, Merlin L. Bruening
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A β-Galactosidase-Activated Fluorogenic Reporter for the Detection of Gastric Cancer In Vivo and in Urine Anal. Chem. (IF 7.4) Pub Date : 2024-04-12 Mengya Yu, Zhenqi Meng, Shujuan Yi, Jianjiao Chen, Weiping Xu, Bankang Ruan, Junjian Wang, Fanghai Han, Jiaguo Huang
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Molecular Imprinting-Based SERS Detection Strategy for the Large-Size Protein Quantitation and Curbing Non-Specific Recognition Anal. Chem. (IF 7.4) Pub Date : 2024-04-12 Xuan Chen, Abbas Ostovan, Maryam Arabi, Yunqing Wang, Lingxin Chen, Jinhua Li
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Continuously Tunable MOFs Enable Precise Mass Transfer for High-Performance Isomer Separation Anal. Chem. (IF 7.4) Pub Date : 2024-04-12 Yuan-Xiao Gao, Xuan-Nuo Yi, Zhe-Chen Tang, Han Yang, Wei Wang, Ming Xu, Zhi-Yuan Gu
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Allosteric Activator-Regulated CRISPR/Cas12a System Enables Biosensing and Imaging of Intracellular Endogenous and Exogenous Targets Anal. Chem. (IF 7.4) Pub Date : 2024-04-11 Qing-Nan Li, Ai-Xin Ma, Dong-Xia Wang, Zhi-Qi Dai, Shun-Li Wu, Sha Lu, Li−Na Zhu, Hong-Xin Jiang, Dai-Wen Pang, De-Ming Kong
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Multiparameter Sensing of Oxygen and pH at Biological Interfaces via Hyperspectral Imaging of Luminescent Sensor Nanoparticles ACS Sens. (IF 8.9) Pub Date : 2024-04-12 Zsófia Bognár, Maria Mosshammer, Kasper E. Brodersen, Elena Bollati, Róbert E. Gyurcsányi, Michael Kühl