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Administration and effects of beta blockers and oxandrolone in severely burned adults: a post hoc analysis of the RE-ENERGIZE trial Burns Trauma (IF 5.3) Pub Date : 2024-04-22 Gabriel Hundeshagen, Elisabeth Blears, Viktoria Mertin, Andrew G Day, Alen Palackic, Christian Tapking, Valentin Haug, Ulrich Kneser, Björn Bliesener, Adriana C Panayi, Ariel Aballay, Francois Depret, Christian Stoppe, Daren K Heyland
Background Prospective randomized trials in severely burned children have shown the positive effects of oxandrolone (OX), beta blockers (BB) and a combination of the two (BBOX) on hypermetabolism, catabolism and hyperinflammation short- and long-term post-burn. Although data on severely burned adults are lacking in comparison, BB, OX and BBOX appear to be commonly employed in this patient population
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Goodbye Hartmann trial: a prospective, international, multicenter, observational study on the current use of a surgical procedure developed a century ago World J. Emerg. Surg. (IF 8.0) Pub Date : 2024-04-16 Gennaro Perrone, Mario Giuffrida, Fikri Abu-Zidan, Vitor F. Kruger, Marco Livrini, Gabriele Luciano Petracca, Giorgio Rossi, Antonio Tarasconi, Brian W. C. A. Tian, Elena Bonati, Ricardo Mentz, Federico N. Mazzini, Juan P. Campana, Elisabeth Gasser, Reinhold Kafka-Ritsch, Daniel M. Felsenreich, Christopher Dawoud, Stefan Riss, Carlos Augusto Gomes, Felipe Couto Gomes, Ricardo Alessandro Teixeira Gonzaga
Literature suggests colonic resection and primary anastomosis (RPA) instead of Hartmann’s procedure (HP) for the treatment of left-sided colonic emergencies. We aim to evaluate the surgical options globally used to treat patients with acute left-sided colonic emergencies and the factors that leading to the choice of treatment, comparing HP and RPA. This is a prospective, international, multicenter
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CT brain perfusion patterns and clinical outcome after successful cardiopulmonary resuscitation: A pilot study Resuscitation (IF 6.5) Pub Date : 2024-04-16 Arsany Hakim, Mattia Branca, Christoph Kurmann, Benedikt Wagner, Manuela Iten, Matthias Hänggi, Franca Wagner
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Cardiac arrest: Treatment is prevention? Resuscitation (IF 6.5) Pub Date : 2024-04-16 Alexis Descatha, Dominique Savary
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Alternative defibrillation strategies: More answers and more questions Resuscitation (IF 6.5) Pub Date : 2024-04-11 Tommaso Scquizzato, Markus B. Skrifvars
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Can small bowel obstruction during pregnancy be treated with conservative management? A review World J. Emerg. Surg. (IF 8.0) Pub Date : 2024-04-10 Xiao Shuang Ling, Wei Cheng Anthony Brian Tian, Goran Augustin, Fausto Catena
Small bowel obstruction can occur during pregnancy, which, if missed, can lead to dire consequences for both the mother and foetus. Management of this condition usually requires surgical intervention. However, only a small number of patients are treated conservatively. The objective was to review the literature to determine the feasibility of conservative management for small bowel obstruction. A systematic
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Norepinephrine or just more epinephrine: Which is the best vasopressor for post-arrest shock? Resuscitation (IF 6.5) Pub Date : 2024-04-10 Nicholas J. Johnson, Ari Moskowitz
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Organ donation after extracorporeal cardiopulmonary resuscitation for refractory out-of-hospital cardiac arrest in a metropolitan cardiac arrest centre in Milan, Italy Resuscitation (IF 6.5) Pub Date : 2024-04-10 Matteo Aldo Bonizzoni, Tommaso Scquizzato, Marina Pieri, Silvia Delrio, Pasquale Nardelli, Alessandro Ortalda, Antonio Dell'Acqua, Anna Mara Scandroglio, ECPR-CARE Collaborators, Otello Giancarlo Turla, Claudia Francescon, Andrea Gambirasio, Tommaso Scaglia
Extracorporeal cardiopulmonary resuscitation (ECPR) may improve survival in refractory out-of-hospital cardiac arrest (OHCA) but also expand the donor pool as these patients often become eligible for organ donation. Our aim is to describe the impact of organ donation in OHCA patients treated with ECPR in a high-volume cardiac arrest centre. Rate of organ donation (primary outcome), organs harvested
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Recalled experience of death: Disinhibition not degeneration in relation to death facilitates inner states of lucid hyperconsciousness with novel cognitive insights Resuscitation (IF 6.5) Pub Date : 2024-04-10 Sam Parnia, Jignesh Patel, Benjamin M. Bloom, Erik Kulstad, Charles D. Deakin, Rebecca Spiegel
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Recognizing the fastest growing cause of out-of-hospital cardiac arrest Resuscitation (IF 6.5) Pub Date : 2024-04-09 Aaron M. Orkin, Cameron Dezfulian
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Acne-induced pathological scars: pathophysiology and current treatments Burns Trauma (IF 5.3) Pub Date : 2024-04-06 Wanyu Xu, Dorsa Gholamali Sinaki, Yuchen Tang, Yunsheng Chen, Yixin Zhang, Zheng Zhang
Acne is a common chronic inflammatory dermatosis that can lead to pathological scars (PSs, divided into hypertrophic scars and keloids). These kinds of abnormal scars seriously reduce the quality of life of patients. However, their mechanism is still unclear, resulting in difficult clinical prevention, unstable treatment effects and a high risk of recurrence. Available evidence supports inflammatory
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Follow up of cardiac arrest survivors: Survey of French intensivists practices Resuscitation (IF 6.5) Pub Date : 2024-04-05 Marine Paul, Julie Paquereau, Stéphane Legriel, Alain Cariou
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Outcomes of a proactive first responder system for out-of-hospital cardiac arrests Resuscitation (IF 6.5) Pub Date : 2024-04-04 Adam J.R. Watson, Andrew Cumpstey, Jack Ansell, Martina Brown, Charles D. Deakin
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Good outcome prediction after out-of-hospital cardiac arrest: A prospective multicenter observational study in Korea (the KORHN-PRO registry) Resuscitation (IF 6.5) Pub Date : 2024-04-04 Hyo Jin Bang, Chun Song Youn, Claudio Sandroni, Kyu Nam Park, Byung Kook Lee, Sang Hoon Oh, In Soo Cho, Seung Pill Choi, on behalf of the Korean Hypothermia Network Investigators
To assess the ability of clinical examination, biomarkers, electrophysiology and brain imaging, individually or in combination to predict good neurological outcomes at 6 months after CA. This was a retrospective analysis of the Korean Hypothermia Network Prospective Registry 1.0, which included adult out-of-hospital cardiac arrest (OHCA) patients (≥18 years). Good outcome predictors were defined as
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A retrospective comparison of mechanical cardio-pulmonary ventilation and manual bag valve ventilation in non-traumatic out-of-hospital cardiac arrests: A study from the Belgian cardiac arrest registry Resuscitation (IF 6.5) Pub Date : 2024-04-04 Stefano Malinverni, Stéphan Wilmin, Diane de Longueville, Mathilde Sarnelli, Griet Vermeulen, Mahmoud Kaabour, Marc Van Nuffelen, Ives Hubloue, Simon Scheyltjens, Alessandro Manara, Pierre Mols, Jean-Christophe Richard, Francis Desmet
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Controlled donation after circulatory death in post-cardiac arrest patients: Estimates from a large registry Resuscitation (IF 6.5) Pub Date : 2024-04-04 Marie Renaudier, Yannick Binois, Florence Dumas, Lionel Lamhaut, Frankie Beganton, Daniel Jost, Julien Charpentier, Olivier Lesieur, Eloi Marijon, Xavier Jouven, Alain Cariou, Wulfran Bougouin, Sudden Death Expertise Centre investigators
Controlled donation after circulatory death (cDCD) in post-anoxic brain injury is a valuable source of organs that is still underused in some countries. We assessed the number of potential cDCD donors after out-of-hospital cardiac arrest (OHCA) in Paris and its suburbs and extrapolated the results to the French population. Using the large regional registry of the Great Paris area, we prospectively
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A retrospective, multi-agency ‘target trial emulation’ for the comparison of post-resuscitation epinephrine to norepinephrine Resuscitation (IF 6.5) Pub Date : 2024-04-04 Tanner Smida, Remle P. Crowe, P.S. Martin, James F. Scheidler, Bradley S. Price, James M. Bardes
Epinephrine and norepinephrine are the two most commonly used prehospital vasopressors in the United States. Prior studies have suggested that use of a post-ROSC epinephrine infusion may be associated with increased rearrest and mortality in comparison to use of norepinephrine. We used target trial emulation methodology to compare the rates of rearrest and mortality between the groups of OHCA patients
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Association between survival and number of shocks for pulseless ventricular arrhythmias during pediatric in-hospital cardiac arrest in a national registry Resuscitation (IF 6.5) Pub Date : 2024-04-04 Sarah E. Haskell, Derek Hoyme, M. Bridget Zimmerman, Ron Reeder, Saket Girotra, Tia T. Raymond, Ricardo A. Samson, Marc Berg, Robert A. Berg, Vinay Nadkarni, Dianne L. Atkins, the American Heart Association's Get With The Guidelines®-Resuscitation Investigators
Annually 15,200 children suffer an in-hospital cardiac arrest (IHCA) in the US. Ventricular fibrillation or pulseless ventricular tachycardia (VF/pVT) is the initial rhythm in 10–15% of these arrests. We sought to evaluate the association of number of shocks and early dose escalation with survival for initial VF/pVT in pediatric IHCA. Using 2000–2020 data from the American Heart Association’s (AHA)
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Accuracy of etiological classification of out-of-hospital cardiac arrest: A scoping review Resuscitation (IF 6.5) Pub Date : 2024-04-04 Sedigheh Shaeri, Julie Considine, Katie N. Dainty, Theresa Mariero Olasveengen, Laurie J. Morrison
The Utstein reporting template classifies the etiology of OHCA into “presumed cardiac” and “obvious non-cardiac” or “medical” and “non-medical” categories; however, the accuracy of these classifications is unclear. Ascertaining more accurately the etiology of OHCA is important to tailor advanced life support and identify etiologically consistent patient cohorts for reporting incidence and outcome and
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The effects of bystander interventions for foreign body airway obstruction on survival and neurological outcomes: Findings of the MOCHI registry Resuscitation (IF 6.5) Pub Date : 2024-04-04 Tatsuya Norii, Yutaka Igarashi, Yudai Yoshino, Shunichiro Nakao, MingAn Yang, Danielle Albright, David P. Sklar, Cameron Crandall
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Toxicological profile using mass spectrometry in sudden cardiac arrest survivors admitted to a tertiary centre Resuscitation (IF 6.5) Pub Date : 2024-04-04 Niels Kjær Stampe, Charlotte Glinge, Brian Schou Rasmussen, Priya Bhardwaj, Kristian Linnet, Reza Jabbari, Christian Paludan-Müller, Christian Hassager, Jesper Kjærgaard, Jacob Tfelt-Hansen, Bo Gregers Winkel
There has been no previous thorough toxicological examination of a cohort of patients with resuscitated sudden cardiac arrest. We aimed to determine the qualitative and quantitative drug composition in a resuscitated sudden cardiac arrest population, using forensic toxicology, with focus on prescribed, non-prescribed, and commonly abused drugs. Individuals aged 18–90 years with resuscitated sudden
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Spreading awareness about automated external defibrillators by using location-based mobile game called geocaching Resuscitation (IF 6.5) Pub Date : 2024-04-03 Nino Fijačko, Špela Metličar, Robert Greif
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The experiences of cardiac arrest survivors and their key supporters following cardiac arrest: A systematic review and meta-ethnography Resuscitation (IF 6.5) Pub Date : 2024-03-26 Charlotte Southern, Elizabeth Tutton, Katie N. Dainty, Kate Seers, Nathan A. Pearson, Keith Couper, David R. Ellard, Gavin D. Perkins, Kirstie L. Haywood
To review qualitative studies on the experience of sudden cardiac arrest survival from the perspective of both survivors and their key supporters, including family/close friends. A seven-step meta-ethnography and synthesis of qualitative evidence was undertaken, informed by the Meta-Ethnography Reporting Guidelines (eMERGe). Four major databases were searched (Medline, EMBASE, CINAHL, PsycINFO; January
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Strategic placement of automated external defibrillators at city bicycle-sharing stations: Exploring the potential Resuscitation (IF 6.5) Pub Date : 2024-03-24 Nino Fijačko, Inja Dokl, Špela Metličar, Robert Greif
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Resuscitation (un-)wanted: Does anyone care? A retrospective real data analysis Resuscitation (IF 6.5) Pub Date : 2024-03-24 Dennis Rupp, Nils Heuser, Martin Christian Sassen, Susanne Betz, Christian Volberg, Susanne Glass
In case of out-of-hospital cardiac arrest (OHCA) personnel of the emergency medical services (EMS) are regularly confronted with advanced directives (AD) and do-not-attempt-resuscitation (DNACPR) orders. The authors conducted a retrospective analysis of EMS operation protocols to examine the prevalence of DNACPR in case of OHCA and the influence of a presented DNACPR on CPR-duration, performed Advanced-Life-Support
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The impact of alternate defibrillation strategies on shock-refractory and recurrent ventricular fibrillation: A secondary analysis of the DOSE VF cluster randomized controlled trial Resuscitation (IF 6.5) Pub Date : 2024-03-24 Sheldon Cheskes, Ian R. Drennan, Linda Turner, Sandeep V. Pandit, Paul Dorian
The DOSE VF randomized controlled trial (RCT) employed a pragmatic definition of refractory ventricular fibrillation (VF after three successive shocks). However, it remains unclear whether the underlying rhythm during the first three shocks was shock-refractory or recurrent VF. To explore the relationship between alternate defibrillation strategies employed during the DOSE VF RCT and the type of VF
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Pediatric out-of-hospital cardiac arrest still needs more attention Resuscitation (IF 6.5) Pub Date : 2024-03-22 Ivie D. Esangbedo
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Reply to addressing the need for bilateral carotid evaluation in doppler monitoring studies for enhanced CPR outcomes Resuscitation (IF 6.5) Pub Date : 2024-03-22 Shuo Wang, Chunsheng Li
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Heroism, futility, and lactate physiology Resuscitation (IF 6.5) Pub Date : 2024-03-22 Zachary Shinar, Dinis Dos Reis Miranda
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Endotracheal epinephrine at standard versus high dose for resuscitation of asystolic newborn lambs Resuscitation (IF 6.5) Pub Date : 2024-03-22 Graeme R. Polglase, Yoveena Brian, Darcy Tantanis, Douglas A. Blank, Shiraz Badurdeen, Kelly J. Crossley, Martin Kluckow, Andrew W. Gill, Emily Camm, Robert Galinsky, Nils Thomas Songstad, Claus Klingenberg, Stuart B. Hooper, Calum T. Roberts
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How can we interpret the unexpected results in two pilot trials comparing thiamine to placebo after cardiac arrest? Resuscitation (IF 6.5) Pub Date : 2024-03-22 Markus B Skrifvars
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Open for business: The blood–brain barrier after cardiac arrest Resuscitation (IF 6.5) Pub Date : 2024-03-22 David J. Barton, Jonathan Elmer
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Textbook outcome in urgent early cholecystectomy for acute calculous cholecystitis: results post hoc of the S.P.Ri.M.A.C.C study World J. Emerg. Surg. (IF 8.0) Pub Date : 2024-03-21 Paola Fugazzola, Silvia Carbonell-Morote, Lorenzo Cobianchi, Federico Coccolini, Juan Jesús Rubio-García, Massimo Sartelli, Walter Biffl, Fausto Catena, Luca Ansaloni, Jose Manuel Ramia
A textbook outcome patient is one in which the operative course passes uneventful, without complications, readmission or mortality. There is a lack of publications in terms of TO on acute cholecystitis. The objective of this study is to analyze the achievement of TO in patients with urgent early cholecystectomy (UEC) for Acute Cholecystitis. and to identify which factors are related to achieving TO
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A meta-analysis and trial sequential analysis of randomised controlled trials comparing nonoperative and operative management of chest trauma with multiple rib fractures World J. Emerg. Surg. (IF 8.0) Pub Date : 2024-03-19 Ryo Hisamune, Mako Kobayashi, Karin Nakasato, Taiga Yamazaki, Noritaka Ushio, Katsunori Mochizuki, Akira Takasu, Kazuma Yamakawa
Operative treatment of traumatic rib fractures for better outcomes remains under debate. Surgical stabilization of rib fractures has dramatically increased in the last decade. This study aimed to perform a systematic review and meta-analysis of randomised controlled trials (RCTs) to assess the effectiveness and safety of operative treatment compared to conservative treatment in adult patients with
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Effectiveness and safety of tourniquet utilization for civilian vascular extremity trauma in the pre-hospital settings: a systematic review and meta-analysis World J. Emerg. Surg. (IF 8.0) Pub Date : 2024-03-19 Ying-Chih Ko, Tou-Yuan Tsai, Chien-Kai Wu, Kai-Wei Lin, Ming-Ju Hsieh, Tzu-Pin Lu, Tasuku Matsuyama, Wen-Chu Chiang, Matthew Huei-Ming Ma
Tourniquets (TQ) have been increasingly adopted in pre-hospital settings recently. This study examined the effectiveness and safety of applying TQ in the pre-hospital settings for civilian patients with traumatic vascular injuries to the extremities. We systematically searched the Ovid Embase, PubMed, and Cochrane Central Register of Controlled Trials databases from their inception to June 2023. We
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National Institute on Drug Abuse Clinical Trials Network Meeting Report: Managing Patients Exposed to Xylazine-Adulterated Opioids in Emergency, Hospital and Addiction Care Settings Ann. Emerg. Med. (IF 6.2) Pub Date : 2024-03-16 Jeanmarie Perrone MD, Rachel Haroz MD, Joseph D’Orazio MD, Giacomo Gianotti DVM DVSc, Jennifer Love MD, Matthew Salzman MD, Margaret Lowenstein MD MSHP, Ashish Thakrar MD, Stephanie Klipp RN CARN, Lisa Rae MD, Megan K. Reed PhD MPH, Edward Sisco PhD, Rachel Wightman MD, Lewis S. Nelson MD MBA
Used as a veterinary sedative and not approved for human use, xylazine has been increasingly linked with opioid overdose deaths in the United States. A growing number of people have been exposed to xylazine in the illicit opioid supply (especially fentanyl) or in other drugs, particularly in some areas of the Northeast. Xylazine is an α-2 adrenergic agonist that decreases sympathetic nervous system
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Coronavirus Disease 2019 Infections Among Emergency Health Care Personnel: Impact on Delivery of United States Emergency Medical Care, 2020 Ann. Emerg. Med. (IF 6.2) Pub Date : 2024-03-16 Kurt D. Weber MD, William Mower MD PhD, Anusha Krishnadasan PhD, Nicholas M. Mohr MD MS, Juan Carlos Montoy MD PhD, Robert M. Rodriguez MD, Philip A. Giordano MD, Patrick Ten Eyck PhD, Karisa K. Harland PhD, Kelli Wallace MS, Lawrence Clifford McDonald MD, Preeta K. Kutty MD MPH, Elisabeth M. Hesse MD MTM&H, David A. Talan MD, Project COVERED Emergency Department Network, Monica Bahamon MPH, Jestin
In the early months of the coronavirus disease 2019 (COVID-19) pandemic and before vaccine availability, there were concerns that infected emergency department (ED) health care personnel could present a threat to the delivery of emergency medical care. We examined how the pandemic affected staffing levels and whether COVID-19 positive staff were potentially infectious at work in a cohort of US ED health
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Not just surviving: Towards a quality standard which meets the care and rehabilitation needs of cardiac arrest survivors and their key supporters Resuscitation (IF 6.5) Pub Date : 2024-03-15 M. Bradfield, K.L. Haywood, M. Mion, A. Kayani, S. Leckey, on behalf of the RCUK Quality Standards Group for Care Rehabilitation of Cardiac Arrest Survivors Key Supporters
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Brain computed tomography after resuscitation from in-hospital cardiac arrest Resuscitation (IF 6.5) Pub Date : 2024-03-15 Cecelia Ratay, Jonathan Elmer, Clifton W. Callaway, Katharyn L. Flickinger, Patrick J. Coppler, on behalf of the University of Pittsburgh Post-Cardiac Arrest Service
Few data characterize the role of brain computed tomography (CT) after resuscitation from in-hospital cardiac arrest (IHCA). We hypothesized that identifying a neurological etiology of arrest or cerebral edema on brain CT are less common after IHCA than after resuscitation from out-of-hospital cardiac arrest (OHCA). We included all patients comatose after resuscitation from IHCA or OHCA in this retrospective
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Together we save: Uniting forces in manual and mechanical CPR Resuscitation (IF 6.5) Pub Date : 2024-03-15 Roos Edgar, Judith L. Bonnes
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Defining, divining, and defeating recurrent cardiac arrest Resuscitation (IF 6.5) Pub Date : 2024-03-12 Nicholas J. Johnson, Thomas D. Rea
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Sound Decisions: Rethinking the Role of Ultrasound-Guided Regional Analgesia in the Emergency Department Ann. Emerg. Med. (IF 6.2) Pub Date : 2024-03-12 Michael Gottlieb MD, Arun Nagdev MD
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Harnessing the Power of Generative AI for Clinical Summaries: Perspectives From Emergency Physicians Ann. Emerg. Med. (IF 6.2) Pub Date : 2024-03-12 Yuval Barak-Corren MD MS, Rebecca Wolf BSc, Ronen Rozenblum MPH PhD, Jessica K. Creedon MD, Susan C. Lipsett MD, Todd W. Lyons MD MPH, Kenneth A. Michelson MD MPH, Kelsey A. Miller MD EdM, Daniel J. Shapiro MD, Ben Y. Reis PhD, Andrew M. Fine MD MPH
The workload of clinical documentation contributes to health care costs and professional burnout. The advent of generative artificial intelligence language models presents a promising solution. The perspective of clinicians may contribute to effective and responsible implementation of such tools. This study sought to evaluate 3 uses for generative artificial intelligence for clinical documentation
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Geriatric Emergency Medication Safety Recommendations (GEMS-Rx): Modified Delphi Development of a High-Risk Prescription List for Older Emergency Department Patients Ann. Emerg. Med. (IF 6.2) Pub Date : 2024-03-12 Rachel M. Skains MD MSPH, Jennifer L. Koehl PharmD BCPS, Amer Aldeen MD, Christopher R. Carpenter MD MSc, Cameron J. Gettel MD MHS, Elizabeth M. Goldberg MD ScM, Ula Hwang MD MPH, Keith E. Kocher MD MPH, Lauren T. Southerland MD MPH, Pawan Goyal MD, Carl T. Berdahl MD MS, Arjun K. Venkatesh MD MBA, Michelle P. Lin MD MPH
Half of emergency department (ED) patients aged 65 years and older are discharged with new prescriptions. Potentially inappropriate prescriptions contribute to adverse drug events. Our objective was to develop an evidence- and consensus-based list of high-risk prescriptions to avoid among older ED patients. We performed a modified, 3-round Delphi process that included 10 ED physician experts in geriatrics
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Sleep apnea, the risk of out-of-hospital cardiac arrest, and potential benefits of continuous positive airway pressure therapy: A nationwide study Resuscitation (IF 6.5) Pub Date : 2024-03-11 Pelpika Qayoumi, Ruben Coronel, Fredrik Folke, Anojhaan Arulmurugananthavadivel, Saaima Parveen, Harman Yonis, Amani Meaidi, Morten Lamberts, Morten Schou, Christian Torp-Pedersen, Gunnar Hilmar Gislason, Talip E. Eroglu
Patients with sleep apnea (SA) are at increased cardiovascular risk. However, little is known about the risk of out-of-hospital cardiac arrest (OHCA) in patients with SA. Therefore, we studied the relation between SA patients who did and did not receive continuous positive airway pressure (CPAP) therapy with OHCA in the general population. Using nationwide databases, we conducted a nested case-control
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The diagnostic accuracy of a shock advisory algorithm in automated external defibrillators in the presence of real-world artifacts Resuscitation (IF 6.5) Pub Date : 2024-03-11 Mengqi Gao, Chenguang Liu, Stacy Gehman, Kevin Burgett, Edward Kompare, Barbara Fink, Dawn B. Jorgenson
The current standards for shock advisory algorithms in AEDs require performance testing on artifact-free ECGs. However, AED analysis in the real world is more challenging due to potential artifacts from various sources (e.g., patient handling, and electromagnetic interference). This retrospective data analysis reports the real-world performance and behavior of a shock advisory algorithm used in three
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Corrigendum to “Tyrphostin reduces the organ injury in haemorrhagic shock: Role of inducible nitric oxide synthase” [Resuscitation 58(3) (2003) 349–361] Resuscitation (IF 6.5) Pub Date : 2024-03-11 Michelle McDonald, Maha Abdelrahman, Salvatore Cuzzocrea, Christoph Thiemermann
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Impact of a COVID-19 code blue protocol on resuscitation care and CPR quality during in-hospital cardiac arrest Resuscitation (IF 6.5) Pub Date : 2024-03-09 Christian Vaillancourt, Manya Charette, Soha Khorsand, Erica Shligold, Chelsea Lanos, Jennifer Dale-Tam, Alexandre Tran, Loree Boyle, Sylvie Aucoin, Jerry Maniate, Hilary Meggison, Michael Hartwick, Glenn Posner
We sought to evaluate the impact of a COVID-19 Code Blue policy on in-hospital cardiac arrest (IHCA) processes of care, cardiopulmonary resuscitation (CPR) quality metrics, and survival to hospital discharge. We completed a health record review of consecutive IHCA for which resuscitation was attempted. We report Utstein outcomes and CPR quality metrics 33 months before (July,2017-March,2020) and after
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Foreign body airway obstruction resulting in out-of-hospital cardiac arrest in Denmark – Incidence, survival and interventions Resuscitation (IF 6.5) Pub Date : 2024-03-09 Signe Amalie Wolthers, Mathias Geldermann Holgersen, Josefine Tangen Jensen, Mikkel Porsborg Andersen, Stig Nikolaj Fasmer Blomberg, Søren Mikkelsen, Helle Collatz Christensen, Theo Walther Jensen
Foreign body airway obstruction (FBAO) stands as an important contributor to accidental fatalities, yet prompt bystander interventions have been shown to improve survival. This study aimed to evaluate the incidence, interventions, and survival outcomes of patients with out-of-hospital cardiac arrest (OHCA) related to FBAO in comparison to patients with non-FBAO OHCA. In this population-based cohort
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The rise of ACS and its importance World J. Emerg. Surg. (IF 8.0) Pub Date : 2024-03-08 Brian WCA Tian
Acute care surgery [ACS] as a model of care and a focused area of specialisation is gaining traction globally [1,2,3]. ACS is seen as a natural evolution of the specialty of trauma. If anything, this restructuring is desperately needed. In the ideal ACS system, I propose that surgeons will be: 1) Exposed to a wide variety of operative procedures and techniques, including the latest laparoscopic and
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Midline Catheters Are the Optimal Vascular Access Device For Managing Septic Shock in the Emergency Department Ann. Emerg. Med. (IF 6.2) Pub Date : 2024-03-08 Alexander Bracey MD, Michael H. Sherman MD MA
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TEMPORARY REMOVAL: Characterising trends in the initiation, timing, and completion of the Recommended Summary Plan for Emergency Care and Treatment (ReSPECT) process: Retrospective analysis of routine data from a large UK hospital trust Resuscitation (IF 6.5) Pub Date : 2024-03-07 Evrim Anik, Adam Hurlow, Desiree Azizoddin, Robert West, Felix Muehlensiepen, Gemma Clarke, Sarah Mitchell, Matthew Allsop
The publisher regrets that this article has been temporarily removed. A replacement will appear as soon as possible in which the reason for the removal of the article will be specified, or the article will be reinstated.
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Peripheral Intravenous Catheters Are Preferable for Emergency Department Patients With Septic Shock Ann. Emerg. Med. (IF 6.2) Pub Date : 2024-03-07 Michael J. Waxman MD MPH, Elissa M. Schechter-Perkins MD MPH
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The Central Venous Catheter Cannot Be Supplanted When It Comes to Septic Shock Ann. Emerg. Med. (IF 6.2) Pub Date : 2024-03-07 Gregory P. Wu MD, Nana Sefa MD MPH
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Emotional distress, social support, and functional dependence predict readiness for hospital discharge in a prospective sample of cognitively intact cardiac arrest survivors Resuscitation (IF 6.5) Pub Date : 2024-03-06 Alexander M. Presciutti, Nomin Enkhtsetseg, Katharyn L. Flickinger, Patrick J. Coppler, Cecelia Ratay, Ankur A. Doshi, Sarah M. Perman, Ana-Maria Vranceanu, Jonathan Elmer
To inform screening, referral and treatment initiatives, we tested the hypothesis that emotional distress, social support, functional dependence, and cognitive impairment within 72 hours prior to discharge predict readiness for discharge in awake and alert cardiac arrest (CA) survivors. This was a secondary analysis of a prospective single-center cohort of CA survivors enrolled between 4/2021 and 9/2022
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Observer-reported cognitive decline in out-of-hospital cardiac arrest survivors and its association with long-term survivor and relative outcomes Resuscitation (IF 6.5) Pub Date : 2024-03-06 Vicky L. Joshi, Britt Borregaard, Tina Broby Mikkelsen, Lars H. Tang, Erik Blennow Nordström, Sofie Moesgaard Bruvik, Anders Wieghorst, Ann-Dorthe Zwisler, Mette Kirstine Wagner
Long-term cognitive decline after out-of-hospital cardiac arrest (OHCA) is still poorly understood. This study describes long-term observer-reported cognitive decline among Danish OHCA survivors, including differences in years since the event, and investigates characteristics and self-reported outcomes associated with observer-reported cognitive decline. Adults who survived an OHCA from 2016 to 2019
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Trends in presumed drug overdose out-of-hospital cardiac arrests in San Francisco, 2015–2023 Resuscitation (IF 6.5) Pub Date : 2024-03-06 Ralph C. Wang, Juan Carlos C. Montoy, Robert M. Rodriguez, James J. Menegazzi, Jeremy Lacocque, David G. Dillon
Estimates of the prevalence of drug-related out of hospital cardiac arrest (OHCA) vary, ranging from 1.8% to 10.0% of medical OHCA. However, studies conducted prior to the recent wave of fentanyl deaths likely underestimate the current prevalence of drug-related OHCA. We evaluated recent trends in drug-related OHCA, hypothesizing that the proportion of presumed drug-related OHCA treated by emergency
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Development and validation of a prehospital termination of resuscitation (TOR) rule for out - of hospital cardiac arrest (OHCA) cases using general purpose artificial intelligence (AI) Resuscitation (IF 6.5) Pub Date : 2024-03-05 Kentaro Kajino, Mohamud R. Daya, Atsunori Onoe, Fumiko Nakamura, Mari Nakajima, Kazuhito Sakuramoto, Marcus Eng Hock Ong, Yasuyuki Kuwagata
Prehospital identification of futile resuscitation efforts (defined as a predicted probability of survival lower than 1%) for out-of-hospital cardiac arrest (OHCA) may reduce unnecessary transport. Reliable prediction variables for OHCA 'termination of resuscitation' (TOR) rules are needed to guide treatment decisions. The Universal TOR rule uses only three variables (Absence of Prehospital ROSC, Event
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Nocardia rubra cell-wall skeleton mitigates whole abdominal irradiation-induced intestinal injury via regulating macrophage function Burns Trauma (IF 5.3) Pub Date : 2024-03-05 Lingling Wu, Long Chen, Huijuan Li, Yawei Wang, Kexin Xu, Wanchao Chen, Aihua Zhang, Yu Wang, Chunmeng Shi
Background Ionizing radiation (IR)-induced intestinal injury is a major side effect and dose-limiting toxicity in patients receiving radiotherapy. There is an urgent need to identify an effective and safe radioprotectant to reduce radiation-induced intestinal injury. Immunoregulation is considered an effective strategy against IR-induced injury. The purpose of this article was to investigate the protective
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The role of the skin microbiome in wound healing Burns Trauma (IF 5.3) Pub Date : 2024-03-05 Yuyan Yang, Jiuzuo Huang, Ang Zeng, Xiao Long, Nanze Yu, Xiaojun Wang
The efficient management of skin wounds for rapid and scarless healing represents a major clinical unmet need. Nonhealing skin wounds and undesired scar formation impair quality of life and result in high healthcare expenditure worldwide. The skin-colonizing microbiota contributes to maintaining an intact skin barrier in homeostasis, but it also participates in the pathogenesis of many skin disorders