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Report-Back of Personal Air Sampling Results and Study Participants' Perceived Knowledge, Attitudes, and Awareness of Air Pollution. Environ. Health Perspect. (IF 10.4) Pub Date : 2023-11-29 Patrick H Ryan,Chris Wolfe,Allison Parsons,Cole Brokamp,Ashley Turner,Sherrill Ingram,Erin Haynes
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Disquieted by Experience: Noise, the Amygdala, and Anxiety-like Responses in Mice. Environ. Health Perspect. (IF 10.4) Pub Date : 2023-11-28 Lindsey Konkel Neabore
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Evaluating the Effect of Gestational Exposure to Perfluorohexane Sulfonate on Placental Development in Mice Combining Alternative Splicing and Gene Expression Analyses. Environ. Health Perspect. (IF 10.4) Pub Date : 2023-11-23 Yihao Zhang,Jia Lv,Yi-Jun Fan,Lin Tao,Jingjing Xu,Weitian Tang,Nan Sun,Ling-Li Zhao,De-Xiang Xu,Yichao Huang
BACKGROUND Perfluorohexane sulfonate (PFHxS) is a frequently detected per- and polyfluoroalkyl substance in most populations, including in individuals who are pregnant, a period critical for early life development. Despite epidemiological evidence of exposure, developmental toxicity, particularly at realistic human exposures, remains understudied. OBJECTIVES We evaluated the effect of gestational exposure
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Projections of Temperature-Related Suicide under Climate Change Scenarios in Japan. Environ. Health Perspect. (IF 10.4) Pub Date : 2023-11-23 Ramita Thawonmas,Masahiro Hashizume,Yoonhee Kim
BACKGROUND The impact of climate change on mental health largely remains to be evaluated. Although growing evidence has reported a short-term association between suicide and temperature, future projections of temperature-attributable suicide have not been thoroughly examined. OBJECTIVES We aimed to project the excess temperature-related suicide mortality in Japan under three climate change scenarios
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Evidence Synthesis of Observational Studies in Environmental Health: Lessons Learned from a Systematic Review on Traffic-Related Air Pollution. Environ. Health Perspect. (IF 10.4) Pub Date : 2023-11-22 Hanna Boogaard,Richard W Atkinson,Jeffrey R Brook,Howard H Chang,Gerard Hoek,Barbara Hoffmann,Sharon K Sagiv,Evangelia Samoli,Audrey Smargiassi,Adam A Szpiro,Danielle Vienneau,Jennifer Weuve,Frederick W Lurmann,Francesco Forastiere
BACKGROUND There is a long tradition in environmental health of using frameworks for evidence synthesis, such as those of the U.S. Environmental Protection Agency for its Integrated Science Assessments and the International Agency for Research on Cancer Monographs. The framework, Grading of Recommendations Assessment, Development, and Evaluation (GRADE), was developed for evidence synthesis in clinical
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Invited Perspective: Systematic Review for Environmental Pollutants-A Work in Progress. Environ. Health Perspect. (IF 10.4) Pub Date : 2023-11-22 Jonathan M Samet
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Low Greenhouse Gas Emission Self-Selective Diets and Risk of Metabolic Syndrome in Adults 40 and Older: A Prospective Cohort Study in South Korea. Environ. Health Perspect. (IF 10.4) Pub Date : 2023-11-17 Li-Juan Tan,Sangah Shin
BACKGROUND The food system accounts for ∼40% of human-generated greenhouse gas (GHG) emissions. Meanwhile, daily diet selection also impacts human nutrition status and health. OBJECTIVES This study aimed to use the alternate Mediterranean Diet (aMED) score to evaluate the quality of a low-GHG emission diet and the association with risk of developing metabolic syndrome (MetS). METHODS A total of 41
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Prenatal Exposure to Perfluoroalkyl Substances and Child Behavior at Age 12: A PELAGIE Mother-Child Cohort Study. Environ. Health Perspect. (IF 10.4) Pub Date : 2023-11-16 Hélène Tillaut,Christine Monfort,Florence Rouget,Fabienne Pelé,Fabrice Lainé,Eric Gaudreau,Sylvaine Cordier,Charline Warembourg,Dave Saint-Amour,Cécile Chevrier
BACKGROUND Per- and polyfluoroalkyl substances (PFAS) are chemical substances spread throughout the environment worldwide. Exposure during pregnancy represents a specific window of vulnerability for child health. OBJECTIVE Our objective was to assess the impact of prenatal exposure to multiple PFAS on emotional and behavioral functions in 12-y-old children. METHOD In the PELAGIE mother-child cohort
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Evaluation of Neural Regulation and Microglial Responses to Brain Injury in Larval Zebrafish Exposed to Perfluorooctane Sulfonate. Environ. Health Perspect. (IF 10.4) Pub Date : 2023-11-15 Shannon E Paquette,Nathan R Martin,April Rodd,Katherine E Manz,Eden Allen,Manuel Camarillo,Hannah I Weller,Kurt Pennell,Jessica S Plavicki
BACKGROUND Per- and polyfluoroalkyl substances (PFAS) are biopersistent, global pollutants. Although some in vitro and epidemiological studies have explored the neurotoxic potential of perfluorooctane sulfonate (PFOS), a prevalent PFAS congener, it is unknown how developmental PFOS exposure affects neuronal signaling, microglia development, and microglial-neuron communication. OBJECTIVES We sought
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Invited Perspective: PFAS Effects on Brain Development-Are Microglia the Missing Link? Environ. Health Perspect. (IF 10.4) Pub Date : 2023-11-15 Elizabeth C Plunk,Ania K Majewska
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From Canaries to Cats: Domestic Animals as Sentinels for Human Exposure Effects. Environ. Health Perspect. (IF 10.4) Pub Date : 2023-11-15 Carrie Arnold
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Associations of Exposure to Air Pollution during the Male Programming Window and Mini-Puberty with Anogenital Distance and Penile Width at Birth and at 1 Year of Age in the Multicenter U.S. TIDES Cohort. Environ. Health Perspect. (IF 10.4) Pub Date : 2023-11-15 Emily S Barrett,Sima Sharghi,Sally W Thurston,Marissa Sobolewski Terry,Christine T Loftus,Catherine J Karr,Ruby H N Nguyen,Shanna H Swan,Sheela Sathyanarayana
BACKGROUND Ambient air pollution may be a developmental endocrine disruptor. In animal models, gestational and perinatal exposure to diesel exhaust and concentrated particulate matter alters anogenital distance (AGD), a marker of prenatal androgen activity, in both sexes. Little is known in humans. OBJECTIVES We examined exposure to fine particulate matter (PM2.5) and nitrogen dioxide (NO2) in relation
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Adult Organophosphate and Carbamate Insecticide Exposure and Sperm Concentration: A Systematic Review and Meta-Analysis of the Epidemiological Evidence. Environ. Health Perspect. (IF 10.4) Pub Date : 2023-11-15 Lauren B Ellis,Karen Molina,C Rebecca Robbins,Marlaina Freisthler,Daria Sgargi,Daniele Mandrioli,Melissa J Perry
BACKGROUND Evidence of the negative impacts of contemporary use insecticides on sperm concentration has increased over the last few decades; however, meta-analyses on this topic are rare. OBJECTIVES This investigation assessed the qualitative and quantitative strength of epidemiological evidence regarding adult exposure to two classes of contemporary use insecticides-organophosphates (OPs) and N-methyl
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Potential Policy and Community Implications of Equitable Organic Waste, Compost, and Urban Agricultural Systems in the United States. Environ. Health Perspect. (IF 10.4) Pub Date : 2023-11-15 Samantha M Hall,Vidya Tikku,Wendy J Heiger-Bernays
BACKGROUND Urban organic waste diverted from landfills for use as compost feedstock may help mitigate and adapt to the effects of our changing climate. Yet, compost produced from urban food and yard waste is often a source of contaminants harmful to human and environmental health. Efforts by multiple municipalities are increasing residential and commercial food and yard waste collection; however, finished
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Invited Perspective: Risk of Bias Assessments, Target Trials, and the Strengths of Environmental Epidemiology. Environ. Health Perspect. (IF 10.4) Pub Date : 2023-11-15 Jonathan Huang
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Contrasting Health Outcomes following a Severe Smoke Episode and Ambient Air Pollution in Early Life: Findings from an Australian Data Linkage Cohort Study of Hospital Utilization. Environ. Health Perspect. (IF 10.4) Pub Date : 2023-11-14 Myriam Ziou,Caroline X Gao,Amanda J Wheeler,Graeme R Zosky,Nicola Stephens,Luke D Knibbs,Shannon M Melody,Alison J Venn,Marita F Dalton,Shyamali C Dharmage,Fay H Johnston
BACKGROUND Episodic spikes in air pollution due to landscape fires are increasing, and their potential for longer term health impacts is uncertain. OBJECTIVE Our objective is to evaluate associations between exposure in utero and in infancy to severe pollution from a mine fire, background ambient air pollution, and subsequent hospital care. METHODS We linked health records of births, emergency department
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Quantifying Enteropathogen Contamination along Chicken Value Chains in Maputo, Mozambique: A Multidisciplinary and Mixed-Methods Approach to Identifying High Exposure Settings. Environ. Health Perspect. (IF 10.4) Pub Date : 2023-11-14 Frederica Lamar,Hermógenes N Mucache,Amelia Mondlane-Milisse,Kelsey J Jesser,Courtney Victor,José M Fafetine,Joaquim Ângelo Osvaldo Saíde,Eric M Fèvre,Bethany A Caruso,Matthew C Freeman,Karen Levy
BACKGROUND Small-scale poultry production is widespread and increasing in low- and middle-income countries (LMICs). Exposure to enteropathogens in poultry feces increases the hazard of human infection and related sequela, and the burden of disease due to enteric infection in children <5 y in particular is substantial. Yet, the containment and management of poultry-associated fecal waste in informal
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Prenatal Exposure to PFAS, Associations with Preterm Birth and Modification by Maternal Estrogen Levels: The Maoming Birth Study. Environ. Health Perspect. (IF 10.4) Pub Date : 2023-11-14 Xiao-Di Qin,Yang Zhou,Michael S Bloom,Zhengmin Min Qian,Sarah Dee Geiger,Michael G Vaughn,Chu Chu,Qing-Qing Li,Bo-Yi Yang,Li-Wen Hu,Yunjiang Yu,Xiao-Wen Zeng,Guang-Hui Dong
BACKGROUND Estrogens play a critical role in parturition, and poly- and perfluoroalkyl substances (PFAS), which have estrogenic effects, have been associated with preterm birth. However, the impact of estrogens on the association between PFAS and preterm birth is unknown. OBJECTIVE The objective of this study is to investigate if estrogens modified the association between PFAS and preterm birth, using
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Examining Exposure Differences between Residential and Smartphone Mobility-Based Greenness in a Cohort of the Nurses' Health Study. Environ. Health Perspect. (IF 10.4) Pub Date : 2023-11-14 Grete E Wilt,Charlotte Roscoe,Cindy R Hu,Hari S Iyer,Unnati V Mehta,Brent A Coull,Jaime E Hart,Steven Gortmaker,Francine Laden,Peter James
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Digging into Exposure Disparities: Mapping Lead Service Lines in New York City. Environ. Health Perspect. (IF 10.4) Pub Date : 2023-11-03 Carrie Arnold
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Opportunities to Interrupt Transmission of Enteropathogens of Poultry Origin in Maputo, Mozambique: A Transmission Model Analysis. Environ. Health Perspect. (IF 10.4) Pub Date : 2023-11-01 Kayoko Shioda,Andrew F Brouwer,Frederica Lamar,Hermógenes N Mucache,Karen Levy,Matthew C Freeman
BACKGROUND The burden of diarrheal diseases remains high among children in low-income countries. Enteropathogens are challenging to control because they are transmitted via multiple pathways. Chickens are an important animal protein source, but live chickens and their products are often highly contaminated with enteropathogens. OBJECTIVES We conducted this study to a) understand the contribution of
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Global Air Pollutant Phenanthrene and Arrhythmic Outcomes in a Mouse Model. Environ. Health Perspect. (IF 10.4) Pub Date : 2023-11-01 Sana Yaar,Tatiana S Filatova,Ellie England,Shiva N Kompella,Jules C Hancox,David A Bechtold,Luigi Venetucci,Denis V Abramochkin,Holly A Shiels
BACKGROUND The three-ringed polycyclic aromatic hydrocarbon (PAH) phenanthrene (Phe) has been implicated in the cardiotoxicity of petroleum-based pollution in aquatic systems, where it disrupts the contractile and electrical function of the fish heart. Phe is also found adsorbed to particulate matter and in the gas phase of air pollution, but to date, no studies have investigated the impact of Phe
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Xenobiotic Exposure and Migraine-Associated Signaling: A Multimethod Experimental Study Exploring Cellular Assays in Combination with Ex Vivo and In Vivo Mouse Models. Environ. Health Perspect. (IF 10.4) Pub Date : 2023-11-01 Rikke H Rasmussen,Sarah L Christensen,Kirstine Calloe,Brian Skriver Nielsen,Anders Rehfeld,Thomas E Taylor-Clark,Kristian A Haanes,Olivier Taboureau,Karine Audouze,Dan A Klaerke,Jes Olesen,David M Kristensen
BACKGROUND Mechanisms for how environmental chemicals might influence pain has received little attention. Epidemiological studies suggest that environmental factors such as pollutants might play a role in migraine prevalence. Potential targets for pollutants are the transient receptor potential (TRP) channels ankyrin 1 (TRPA1) and vanilloid 1 (TRPV1), which on activation release pain-inducing neuropeptide
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Invited Perspective: The Silent Threat-Air Pollution's Link to Arrhythmias. Environ. Health Perspect. (IF 10.4) Pub Date : 2023-11-01 Flavia Bonalumi,Michele Miragoli
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Research Recommendations for Selected IARC-Classified Agents: Impact and Lessons Learned. Environ. Health Perspect. (IF 10.4) Pub Date : 2023-10-30 Michelle C Turner,Vincent Cogliano,Kathryn Guyton,Federica Madia,Kurt Straif,Elizabeth M Ward,Mary K Schubauer-Berigan
BACKGROUND The International Agency for Research on Cancer (IARC) Monographs program assembles expert working groups who publish a critical review and evaluation of data on agents of interest. These comprehensive reviews provide a unique opportunity to identify research needs to address classification uncertainties. A multidisciplinary expert review and workshop held in 2009 identified research gaps
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Invited Perspective: How Far Have We Come? Revisiting a 2009 Report on Occupational Cancer Research Recommendations. Environ. Health Perspect. (IF 10.4) Pub Date : 2023-10-30 Mark P Purdue,Mary H Ward
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Per- and Polyfluoroalkyl Substances and Anti-Müllerian Hormone Concentrations in Two Preconception Cohort Studies. Environ. Health Perspect. (IF 10.4) Pub Date : 2023-10-26 Lauren A Wise,Tanran R Wang,Ellen M Mikkelsen,Amelia K Wesselink,Antonia M Calafat,Ganesa Wegienka,Ruth J Geller,Chad M Coleman,Mary D Willis,Erica E Marsh,Samantha Schildroth,Julianne C Botelho,Geralyn Messerlian-Lambert,Elizabeth E Hatch
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Fine Particulate Matter Metal Composition, Oxidative Potential, and Adverse Birth Outcomes in Los Angeles. Environ. Health Perspect. (IF 10.4) Pub Date : 2023-10-25 Qi Meng,Jonathan Liu,Jiaqi Shen,Irish Del Rosario,Pascale S J Lakey,Manabu Shiraiwa,Jason Su,Scott Weichenthal,Yifang Zhu,Farzan Oroumiyeh,Suzanne E Paulson,Michael Jerrett,Beate Ritz
BACKGROUND Although many studies have linked prenatal exposure to PM2.5 to adverse birth outcomes, little is known about the effects of exposure to specific constituents of PM2.5 or mechanisms that contribute to these outcomes. OBJECTIVES Our objective was to investigate effects of oxidative potential and PM2.5 metal components from non-exhaust traffic emissions, such as brake and tire wear, on the
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Ambient Air Pollution Exposure and Cerebral White Matter Hyperintensities in Older Adults: A Cross-Sectional Analysis in the Three-City Montpellier Study. Environ. Health Perspect. (IF 10.4) Pub Date : 2023-10-25 Jeanne Duchesne,Isabelle Carrière,Sylvaine Artero,Adam M Brickman,Jerome Maller,Chantal Meslin,Jie Chen,Danielle Vienneau,Kees de Hoogh,Bénédicte Jacquemin,Claudine Berr,Marion Mortamais
BACKGROUND Growing epidemiological evidence suggests an adverse relationship between exposure to air pollutants and cognitive health, and this could be related to the effect of air pollution on vascular health. OBJECTIVE We aim to evaluate the association between air pollution exposure and a magnetic resonance imaging (MRI) marker of cerebral vascular burden, white matter hyperintensities (WMH). METHODS
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Stirring Up Trouble? Forest Disturbance and the Spread of a Fungal Disease. Environ. Health Perspect. (IF 10.4) Pub Date : 2023-10-25 Olayinka Osuolale
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Seminar: Extracellular Vesicles as Mediators of Environmental Stress in Human Disease. Environ. Health Perspect. (IF 10.4) Pub Date : 2023-10-20 Vrinda Kalia,Andrea A Baccarelli,Christine Happel,Jonathan A Hollander,Anne Marie Jukic,Kimberly A McAllister,Ramkumar Menon,Bruce A Merrick,Aleksander Milosavljevic,Lingamanaidu V Ravichandran,Matthew E Roth,Anita Subramanian,Frederick L Tyson,Leroy Worth,Daniel T Shaughnessy
BACKGROUND Extracellular vesicles (EVs), membrane-bound particles containing a variety of RNA types, DNA, proteins, and other macromolecules, are now appreciated as an important means of communication between cells and tissues, both in normal cellular physiology and as a potential indicator of cellular stress, environmental exposures, and early disease pathogenesis. Extracellular signaling through
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Association of Prenatal Exposure to Organophosphate, Pyrethroid, and Neonicotinoid Insecticides with Child Neurodevelopment at 2 Years of Age: A Prospective Cohort Study. Environ. Health Perspect. (IF 10.4) Pub Date : 2023-10-19 Aizhen Wang,Yanjian Wan,Gaga Mahai,Xi Qian,Yuanyuan Li,Shunqing Xu,Wei Xia
BACKGROUND Widespread insecticide exposure might be a risk factor for neurodevelopment of our children, but few studies examined the mixture effect of maternal coexposure to organophosphate insecticides (OPPs), pyrethroids (PYRs), and neonicotinoid insecticides (NNIs) during pregnancy on child neurodevelopment, and critical windows of exposure are unknown. OBJECTIVES We aimed to evaluate the association
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Association of Redlining and Natural Environment with Depressive Symptoms in Women in the Sister Study. Environ. Health Perspect. (IF 10.4) Pub Date : 2023-10-18 Wei-Lun Tsai,Maliha S Nash,Daniel J Rosenbaum,Steven E Prince,Aimee A D'Aloisio,Megan H Mehaffey,Dale P Sandler,Timothy J Buckley,Anne C Neale
BACKGROUND Improving mental health is recognized as an important factor for achieving global development goals. Despite strong evidence that neighborhood greenery promotes better mental health, there are environmental justice concerns over the distribution of neighborhood greenery. Underlying these concerns are present-day consequences of historical discriminatory financial investment practices, such
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Invited Perspective: Forging a Way Forward Amid the Enduring Impacts of Redlining. Environ. Health Perspect. (IF 10.4) Pub Date : 2023-10-18 Miatta A Buxton,Marie S O'Neill
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Prenatal Exposure to Multiple Endocrine-Disrupting Chemicals and Childhood BMI Trajectories in the INMA Cohort Study. Environ. Health Perspect. (IF 10.4) Pub Date : 2023-10-18 Parisa Montazeri,Nuria Güil-Oumrait,Sandra Marquez,Lourdes Cirugeda,Andrea Beneito,Mònica Guxens,Aitana Lertxundi,Maria-Jose Lopez-Espinosa,Loreto Santa-Marina,Jordi Sunyer,Maribel Casas,Martine Vrijheid
BACKGROUND Prenatal exposure to endocrine-disrupting chemicals (EDCs) may disrupt normal fetal and postnatal growth. Studies have mainly focused on individual aspects of growth at specific time points using single chemical exposure models. However, humans are exposed to multiple EDCs simultaneously, and growth is a dynamic process. OBJECTIVE The objective of this study was to evaluate the associations
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Association between Residential Proximity to Viticultural Areas and Childhood Acute Leukemia Risk in Mainland France: GEOCAP Case-Control Study, 2006-2013. Environ. Health Perspect. (IF 10.4) Pub Date : 2023-10-18 Matthieu Mancini,Denis Hémon,Perrine de Crouy-Chanel,Laurence Guldner,Laure Faure,Jacqueline Clavel,Stéphanie Goujon
BACKGROUND Pesticide exposures are suspected of being a risk factor for several childhood cancers, particularly acute leukemia (AL). Most of the evidence is based on self-reported parental domestic use of pesticides, but some studies have also addressed associations with agricultural use of pesticides near the place of residence. OBJECTIVES The objective of the study was to evaluate the risk of AL
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Beyond Wind and Flood: Review of Cyclone Research Spotlights Trauma Outcomes. Environ. Health Perspect. (IF 10.4) Pub Date : 2023-10-17 Charles Schmidt
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Fanning the Flames: Low-Level Air Pollution and Risk of Surgery or Mortality for Persons with IBD. Environ. Health Perspect. (IF 10.4) Pub Date : 2023-10-16 Wendee Nicole
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Nested Case-Control Studies Investigating Serum Perfluorooctanoate and Perfluorooctane Sulfonate Levels and Pancreatic Ductal Adenocarcinoma in Two Cohorts. Environ. Health Perspect. (IF 10.4) Pub Date : 2023-10-16 Ting Zhang,Sheng Fu,Kai Yu,Demetrius Albanes,Steven C Moore,Mark P Purdue,Rachael Z Stolzenberg-Solomon
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Journal of Health and Pollution: Fostering Equity in Access to Environmental Health Research Evidence. Environ. Health Perspect. (IF 10.4) Pub Date : 2023-10-12 Kalpana Balakrishnan,Joel D Kaufman
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Urinary Glyphosate, 2,4-D and DEET Biomarkers in Relation to Neurobehavioral Performance in Ecuadorian Adolescents in the ESPINA Cohort. Environ. Health Perspect. (IF 10.4) Pub Date : 2023-10-11 Briana N C Chronister,Kun Yang,Audrey R Yang,Tuo Lin,Xin M Tu,Dolores Lopez-Paredes,Harvey Checkoway,Jose Suarez-Torres,Sheila Gahagan,Danilo Martinez,Dana Barr,Raeanne C Moore,Jose R Suarez-Lopez
BACKGROUND Herbicides are the most used class of pesticides worldwide, and insect repellents are widely used globally. Yet, there is a dearth of studies characterizing the associations between these chemical groups and human neurobehavior. Experimental studies suggest that glyphosate and 2,4-dichlorophenoxyacetic acid (2,4-D) herbicides can affect neurobehavior and the cholinergic and glutamatergic
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Assessing Metabolic Differences Associated with Exposure to Polybrominated Biphenyl and Polychlorinated Biphenyls in the Michigan PBB Registry. Environ. Health Perspect. (IF 10.4) Pub Date : 2023-10-10 Susan S Hoffman,Donghai Liang,Robert B Hood,Youran Tan,Metrecia L Terrell,M Elizabeth Marder,Hillary Barton,Melanie A Pearson,Douglas I Walker,Dana Boyd Barr,Dean P Jones,Michele Marcus
BACKGROUND Polybrominated biphenyls (PBB) and polychlorinated biphenyls (PCB) are persistent organic pollutants with potential endocrine-disrupting effects linked to adverse health outcomes. OBJECTIVES In this study, we utilize high-resolution metabolomics (HRM) to identify internal exposure and biological responses underlying PCB and multigenerational PBB exposure for participants enrolled in the
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Characterization of Anxiety-Like Behaviors and Neural Circuitry following Chronic Moderate Noise Exposure in Mice. Environ. Health Perspect. (IF 10.4) Pub Date : 2023-10-05 Xiaoqi Peng,Yunfeng Mao,Yingju Tai,Bin Luo,Qian Dai,Xiyang Wang,Hao Wang,Yue Liang,Ruirui Guan,Chunhua Liu,Yiping Guo,Lin Chen,Zhi Zhang,Haitao Wang
BACKGROUND Commonly encountered nontraumatic, moderate noise is increasingly implicated in anxiety; however, the neural substrates underlying this process remain unclear. OBJECTIVES We investigated the neural circuit mechanism through which chronic exposure to moderate-level noise causes anxiety-like behaviors. METHODS Mice were exposed to chronic, moderate white noise [85 decibel (dB) sound pressure
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Exposure to Particulate Matter Air Pollution and Age of Menarche in a Nationwide Cohort of U.S. Girls. Environ. Health Perspect. (IF 10.4) Pub Date : 2023-10-04 Robert B Hood,Jaime E Hart,Francine Laden,Bernard Rosner,Jorge E Chavarro,Audrey J Gaskins
BACKGROUND It remains unclear whether in utero and childhood exposure to air pollution affects pubertal development, particularly age of menarche in girls. OBJECTIVE The aim of this study was to determine whether residential ambient particulate matter (PM) exposure in utero and during childhood is associated with age of menarche. METHODS We studied 5,201 girls in the Growing Up Today Study 2 (2004-present)
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Ambient PM2.5 Exposure and Bone Homeostasis: Analysis of UK Biobank Data and Experimental Studies in Mice and in Vitro. Environ. Health Perspect. (IF 10.4) Pub Date : 2023-10-04 Qinwen Ge,Sijia Yang,Yu Qian,Jiali Chen,Wenhua Yuan,Sanduo Li,Pinger Wang,Ran Li,Lu Zhang,Guobo Chen,Haidong Kan,Sanjay Rajagopalan,Qinghua Sun,Hou-Feng Zheng,Hongting Jin,Cuiqing Liu
BACKGROUND Previous evidence has identified exposure to fine ambient particulate matter (PM2.5) as a leading risk factor for adverse health outcomes. However, to date, only a few studies have examined the potential association between long-term exposure to PM2.5 and bone homeostasis. OBJECTIVE We sought to examine the relationship between long-term PM2.5 exposure and bone health and explore its potential
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Long-Term Exposure to Walkable Residential Neighborhoods and Risk of Obesity-Related Cancer in the New York University Women's Health Study (NYUWHS). Environ. Health Perspect. (IF 10.4) Pub Date : 2023-10-04 Sandra India-Aldana,Andrew G Rundle,James W Quinn,Tess V Clendenen,Yelena Afanasyeva,Karen L Koenig,Mengling Liu,Kathryn M Neckerman,Lorna E Thorpe,Anne Zeleniuch-Jacquotte,Yu Chen
BACKGROUND Living in neighborhoods with higher levels of walkability has been associated with a reduced risk of obesity and higher levels of physical activity. Obesity has been linked to increased risk of 13 cancers in women. However, long-term prospective studies of neighborhood walkability and risk for obesity-related cancer are scarce. OBJECTIVES We evaluated the association between long-term average
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Invited Perspective: Studying Walkability and Cancer Incidence-A Step in the Right Direction. Environ. Health Perspect. (IF 10.4) Pub Date : 2023-10-04 Charlotte Roscoe,Cindy R Hu,Paul J Villeneuve
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Disparities in Toxic Chemical Exposures and Associated Neurodevelopmental Outcomes: A Scoping Review and Systematic Evidence Map of the Epidemiological Literature. Environ. Health Perspect. (IF 10.4) Pub Date : 2023-09-27 Devon C Payne-Sturges,Tanya Khemet Taiwo,Kristie Ellickson,Haley Mullen,Nedelina Tchangalova,Laura Anderko,Aimin Chen,Maureen Swanson
BACKGROUND Children are routinely exposed to chemicals known or suspected of harming brain development. Targeting Environmental Neuro-Development Risks (Project TENDR), an alliance of >50 leading scientists, health professionals, and advocates, is working to protect children from these toxic chemicals and pollutants, especially the disproportionate exposures experienced by children from families with
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Invited Perspective: Still Beating the Drum-Environmental Health Disparities and Neurodevelopment. Environ. Health Perspect. (IF 10.4) Pub Date : 2023-09-27 Aisha S Dickerson
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Exposure to Perfluoroalkyl Substances and Associations with Pubertal Onset and Serum Reproductive Hormones in a Longitudinal Study of Young Girls in Greater Cincinnati and the San Francisco Bay Area. Environ. Health Perspect. (IF 10.4) Pub Date : 2023-09-26 Susan M Pinney,Cecily S Fassler,Gayle C Windham,Robert L Herrick,Changchun Xie,Lawrence H Kushi,Frank M Biro
BACKGROUND Per- and polyfluoroalkyl substances (PFAS), endocrine disrupting chemicals with worldwide exposure, cause changes in mammary gland development in rodents. A few human studies report delay in pubertal events with increasing perfluorooctanoic acid (PFOA) exposure, but to our knowledge none have examined reproductive hormone levels at thelarche. METHODS In a cohort of Greater Cincinnati (GC)
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Invited Perspective: PFAS and Pubertal Timing in Girls-A Maturing Literature. Environ. Health Perspect. (IF 10.4) Pub Date : 2023-09-26 Emily S Barrett,Zorimar Rivera-Núñez
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Response to "Comment on 'Adoption of Point-of-Use Chlorination for Household Drinking Water Treatment: A Systematic Review'". Environ. Health Perspect. (IF 10.4) Pub Date : 2023-09-26 Yoshika S Crider,Isha Ray,Amy J Pickering
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In Utero Exposure to Metals and Birth Outcomes in an Artisanal and Small-Scale Gold Mining Birth Cohort in Madre de Dios, Peru. Environ. Health Perspect. (IF 10.4) Pub Date : 2023-09-25 Axel J Berky,Caren Weinhouse,Joao Vissoci,Nelson Rivera,Ernesto J Ortiz,Susy Navio,J Jaime Miranda,Andres Mallipudi,Emma Fixen,Heileen Hsu-Kim,William K Pan
BACKGROUND Few birth cohorts in South America evaluate the joint effect of minerals and toxic metals on neonatal health. In Madre de Dios, Peru, mercury exposure is prevalent owing to artisanal gold mining, yet its effect on neonatal health is unknown. OBJECTIVES We aimed to determine whether toxic metals are associated with lower birth weight and shorter gestational age independently of antenatal
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Invited Perspective: An Argument for Changing the Reporting Units for Lead in Blood. Environ. Health Perspect. (IF 10.4) Pub Date : 2023-09-25 Jack Caravanos,Julianne Nassif,Bruce Lanphear,Philip J Landrigan,Howard Hu,Richard Fuller
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Untested, Unsafe? Cannabis Users Show Higher Lead and Cadmium Levels. Environ. Health Perspect. (IF 10.4) Pub Date : 2023-09-25 Nate Seltenrich
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Guest Editorial: Focusing on What Matters Most-Impact. Environ. Health Perspect. (IF 10.4) Pub Date : 2023-09-21 Richard Fuller,David Hanrahan,Ernesto Sanchez-Triana,Janez Potočnik,Robert Watson
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Effect Modifications of Overhead-View and Eye-Level Urban Greenery on Heat-Mortality Associations: Small-Area Analyses Using Case Time Series Design and Different Greenery Measurements. Environ. Health Perspect. (IF 10.4) Pub Date : 2023-09-20 Jinglu Song,Antonio Gasparrini,Thomas Fischer,Kejia Hu,Yi Lu
BACKGROUND The protective effect of urban greenery from adverse heat impacts remains inconclusive. Existing inconsistent findings could be attributed to the different estimation techniques used. OBJECTIVES We investigated how effect modifications of urban greenery on heat-mortality associations vary when using different greenery measurements reflecting overhead-view and eye-level urban greenery. METHODS
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Evaluating Neighborhood-Level Differences in Hair Product Safety by Environmental Working Group Ratings among Retailers in Boston, Massachusetts. Environ. Health Perspect. (IF 10.4) Pub Date : 2023-09-13 Marissa Chan,Shivani Parikh,Derek Shyr,Bhavna Shamasunder,Gary Adamkiewicz,Tamarra James-Todd
BACKGROUND Personal care products are a notable source of exposure to endocrine-disrupting chemicals (EDCs). Racial/ethnic differences in the use of hair products containing EDCs are reported, with women and children of color more commonly using hair products that are hormonally active and contain EDCs than other racial/ethnic groups. There is limited research examining the neighborhood-level social
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Urinary Paraben Concentrations and Associations with the Periconceptional Urinary Metabolome: Untargeted and Targeted Metabolomics Analyses of Participants from the Early Pregnancy Study. Environ. Health Perspect. (IF 10.4) Pub Date : 2023-09-13 Ana K Rosen Vollmar,Nicholas J W Rattray,Yuping Cai,Abhishek Jain,Hong Yan,Nicole C Deziel,Antonia M Calafat,Allen J Wilcox,Anne Marie Z Jukic,Caroline H Johnson
BACKGROUND Parabens, found in everyday items from personal care products to foods, are chemicals with endocrine-disrupting activity, which has been shown to influence reproductive function. OBJECTIVES This study investigated whether urinary concentrations of methylparaben, propylparaben, or butylparaben were associated with the urinary metabolome during the periconceptional period, a critical window