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In vitro and in vivo comparisons of the porous Ti6Al4V alloys fabricated by the selective laser melting technique and a new sintering technique.
Journal of the Mechanical Behavior of Biomedical Materials ( IF 3.9 ) Pub Date : 2018-12-10 , DOI: 10.1016/j.jmbbm.2018.12.007
Ji Li 1 , Zhongli Li 1 , Yueyi Shi 2 , Haoran Wang 1 , Ruiling Li 3 , Jiangping Tu 3 , Gong Jin 4
Affiliation  

A new sintering technique using Ti6Al4V powder suspension was performed to prepare porous Ti6Al4V alloy with 75% porosity. Porous Ti6Al4V alloy with the same porosity fabricated by selective laser melting technique was used as the control. The characteristics, mechanical and biological properties of the two types of porous Ti6Al4V alloys were evaluated by mechanical tests, in vitro cell analysis and implantations. Results indicated that both groups showed good biocompatibility and osteogenic ability. However, microstructure and mechanical properties of the sintered porous Ti6Al4V were more similar to the cancellous bone without obvious stress shielding, and the new type of sample may be more effective in achieving early stability after implantation. Therefore, under the study conditions, this new type of porous alloy prospects a good candidate for biomaterials, especially for repairing bone defects and arthroplasty in orthopedics.



中文翻译:

通过选择性激光熔化技术和新的烧结技术制造的多孔Ti6Al4V合金的体内外比较。

进行了使用Ti6Al4V粉末悬浮液的新烧结技术,以制备具有75%孔隙率的多孔Ti6Al4V合金。通过选择激光熔化技术制备的具有相同孔隙率的多孔Ti6Al4V合金作为对照。通过力学测试,体外细胞分析和植入评估了两种类型的多孔Ti6Al4V合金的特性,力学和生物学性能。结果表明,两组均显示出良好的生物相容性和成骨能力。然而,烧结多孔Ti6Al4V的微观结构和力学性能与松质骨更相似,并且没有明显的应力屏蔽,并且新型样品可能在植入后的早期稳定性方面更有效。因此,在学习条件下,

更新日期:2018-12-10
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