Identification of tumor-initiating populations could provide insights into tumor heterogeneity and responses to treatments, but this has proven difficult in most cancers. Now in Cell Stem Cell, Preussner et al. (2018) provide direct evidence that regenerating muscle satellite cells can be transformed to initiate and propagate rhabdomyosarcoma tumors.

中文翻译：

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倍增的干细胞符合肿瘤发生。

鉴定肿瘤起始人群可以提供有关肿瘤异质性和对治疗的反应的见解，但是事实证明，在大多数癌症中，这很困难。现在在《细胞干细胞》中，Preussner等人。（2018）提供了直接的证据，表明再生的肌肉卫星细胞可以转化为引发和传播横纹肌肉瘤的肿瘤。