Ice-templating combined with indirect 3D printing is proposed as a promising method for preparation of scaffolds with multiscale porosity, including a well-defined interconnected macro-channel network. Robocasting was used as a comparative technique to produce scaffolds with comparable porosity at the introduced macroporosity and the inter-grain microporosity levels. Porosity, phase composition and mechanical stability were measured and compared for bio-scaffolds prepared by both techniques. Comparable total porosities could only be achieved in robocasting by choosing a significantly lower sintering temperature (950 °C vs. 1200 °C). The compressive strength of robocast scaffolds was significantly greater (6.5 ± 1.19 MPa vs. 2.3 ± 1.00 MPa, respectively). However, the increased level of interconnected multiscale porosity coupled to a finer grain size of ice-templated samples sintered at 1200 °C (~ 500 nm vs. 2.5 µm for robocast parts) could prove to be beneficial for the development of highly porous bioactive scaffolds with enhanced biological performance.

提出将冰模板与间接3D打印相结合作为制备具有多尺度孔隙率的脚手架的有前途的方法，包括明确定义的互连宏通道网络。机器人浇铸被用作一种比较技术，以在所引入的大孔隙度和晶粒间微孔隙度水平下生产具有相当孔隙率的支架。测量并比较了通过两种技术制备的生物支架的孔隙率，相组成和机械稳定性。只有通过选择明显较低的烧结温度（950°C与1200°C），才能在机械铸造中获得可比的总孔隙率。机器人支架的抗压强度明显更高（6.5±1.19 MPa与。分别为2.3±1.00 MPa）。但是，相互连接的多尺度孔隙度的增加与在1200°C下烧结的冰样样品的更细粒度（〜500 nm相对于机器人铸件的2.5 µm）相结合，可证明对开发高度多孔的生物活性支架是有益的具有增强的生物学性能。