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Genetic characterization of amyloid-β and tau network spread
Nature Medicine ( IF 82.9 ) Pub Date : 2018-12-03 , DOI: 10.1038/s41591-018-0277-2
Rik Ossenkoppele , Oskar Hansson

Genetic characterization of amyloid-β and tau network spread

Genetic characterization of amyloid-β and tau network spread , Published online: 03 December 2018; doi:10.1038/s41591-018-0277-2

Protein-specific and shared genetic pathways influence the spread of amyloid-β and tau pathology. Hence, distinct gene expression profiles may induce regional vulnerability of the human cortex to the specific proteinopathies of Alzheimer’s disease.


中文翻译:

淀粉样β蛋白和tau网络传播的遗传特征

淀粉样β蛋白和tau网络传播的遗传特征

淀粉样β和tau网络传播的遗传特征,在线发布:2018年12月3日; doi:10.1038 / s41591-018-0277-2

蛋白质特异性和共有的遗传途径影响淀粉样β的扩散和tau病理。因此,不同的基因表达谱可能诱导人类皮质对阿尔茨海默氏病的特定蛋白病的区域脆弱性。
更新日期:2018-12-04
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