Peptides are suitable candidates for templates in the fabrication of various metal nanoparticles (NPs) because of their metal-binding ability and templating effect, which impart physicochemical properties to the produced nanoparticles. Peptide-binding gold nanoparticles (AuNPs) show high catalytic activity that permits their application in oxidation or reduction reactions. Herein, we prepared morphology-controllable AuNPs stabilized by self-assembled tyrosine-rich peptides (YC₇) by varying the pH and YC₇ peptide/Au³⁺ concentration ratio in 2-(N-morpholino)ethanesulfonic acid (MES) buffer solution. The catalytic activities of the YC₇ peptide-stabilized AuNPs (YC₇@AuNPs) were tested for 4-nitrophenol (4-NP) reduction, and kinetic analysis was performed to calculate the apparent rate constants and activation energies. The relatively low activation energy of the YC₇@AuNPs could be explained by the hypothesis that the tyrosine-moiety of YC₇ enriches the electron density of Au metal.

中文翻译：

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纳米金稳定的富含酪氨​​酸的肽自组装及其在还原4-硝基苯酚中的催化活性

肽是各种金属纳米颗粒（NP）制造中模板的合适候选者，因为它们的金属结合能力和模板效应可将所产生的纳米颗粒赋予物理化学性质。结合肽的金纳米颗粒（AuNPs）具有很高的催化活性，使其可用于氧化或还原反应。在这里，我们通过改变2-（N-吗啉代）乙磺酸（MES）缓冲溶液中的pH和YC ₇肽/ Au ^3+的浓度比来制备由可自组装的富含酪氨​​酸的肽（YC ₇）稳定的形态可控的AuNP。。YC ₇肽稳定的AuNPs（YC ₇测试AuNPs的4-硝基苯酚（4-NP）还原，并进行动力学分析以计算表观速率常数和活化能。YC ₇ @AuNPs的活化能相对较低，可以通过以下假设来解释：YC ₇的酪氨酸部分丰富了金金属的电子密度。