Chitosan was functionalized to synthesize Quaternized N-trimethyl chitosan (TMC) and incorporated in polyethersulfone (PES) polymer to fabricate membranes for enhanced antifungal activity and water treatment. The TMC was synthesized from chitosan via reductive alkylation and methylation. The effect of concentration of chitosan and TMC on the properties of functionalized PES membranes was investigated. The membrane with the lowest concentration of TMC 5% (w/w) resulted in the largest average pore size than the PES membrane without chitosan or TMC. The surface wettability was enhanced as contact angle was reduced from 90º to 57º by increasing concentration of TMC to 15% (w/w). The resultant membranes exhibited improved water hydrophilicity, permeability and inhibition against fungal species. The functionalized membranes had shown noticeable antifungal activity against Aspergillus niger in the case of 15% TMC with 72% antifungal activity and 15% chitosan with 63 % antifungal activity against Fusarium solani.

将壳聚糖官能化以合成季铵化N-三甲基壳聚糖（TMC），并掺入聚醚砜（PES）聚合物中以制造膜，以增强抗真菌活性和水处理能力。TMC是由壳聚糖通过还原烷基化和甲基化合成的。研究了壳聚糖和TMC浓度对功能化PES膜性能的影响。与不含壳聚糖或TMC的PES膜相比，具有最低5％TMC（w / w）浓度的膜产生的平均孔径最大。通过将TMC的浓度增加到15％（w / w），将接触角从90º减小到57º，可提高表面润湿性。所得的膜表现出改善的水亲水性，渗透性和对真菌种类的抑制作用。黑曲霉在15％的TMC中具有72％的抗真菌活性，而15％的脱乙酰壳多糖中的63％的抗枯萎镰孢菌具有抗真菌活性。