To the Editor—We thank Garg and colleagues for their letter [1]. Two randomized trials compared albendazole and combination therapy with simultaneous praziquantel and albendazole [2, 3]. In both cases, the radiologic response was better with combination therapy only in patients with >2 viable parenchymal cysts but not in those with ≤2 cysts. These trials were the basis for the distinction in treatment of viable parenchymal disease distinguishing patients with 1 or 2 parenchymal cysts form those with ≥3 parenchymal cysts or viable parenchymal cysticercosis. However, neither of these trials included patients with >20 cysticerci.

中文翻译：

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回复Garg等人，Smith等人以及Persichino和Miller

致编辑-感谢Garg及其同事的来信[1]。两项随机试验比较了阿苯达唑和联合治疗与同时吡喹酮和阿苯达唑[2，3]。在这两种情况下，仅对于> 2个活性实质性囊肿的患者，联合治疗的放射学反应均好，而对≤2个囊肿的患者则无统计学意义。这些试验是区分可生存的实质性疾病的依据，可将具有1个或2个实质性囊肿的患者与≥3个实质性囊肿或生存性实质性囊虫病的患者区分开。但是，这些试验均未包括大于20个囊虫的患者。