Small diameter (diameter < 6 mm) vascular scaffolds lead to increased hemodynamic disturbances and thrombogenic complications which challenged the material scientists. A compatible interface with applicable mechanical properties of scaffolds is the key issue. In this study, 4 mm inner-diameter poly(ε-caprolactone)/polylactic (PCL/PLA) blend foam vascular scaffolds were fabricated by supercritical carbon dioxide via batch foaming. A uniform open-cell morphology on the cross section of PCL/PLA foams was achieved. To improve the porosity and hydrophilicity on the surface of scaffolds, sodium hydroxide solution was used to hydrolyze off PLA phase. Tensile properties, suture retention, bursting resistance and cell culture of PCL/PLA foam scaffolds were also improved and showed a great promise for vascular tissue engineering application.

小直径（直径<6 mm）的血管支架导致血液动力学障碍和血栓形成并发症的增加，这对材料科学家构成了挑战。具有适用的脚手架机械性能的兼容界面是关键问题。在这项研究中，通过分批发泡通过超临界二氧化碳制造了内径为4 mm的聚（ε-己内酯）/聚乳酸（PCL / PLA）混合泡沫血管支架。在PCL / PLA泡沫的横截面上实现了均匀的开孔形态。为了提高支架表面的孔隙率和亲水性，使用氢氧化钠溶液将PLA相水解。PCL / PLA泡沫支架的拉伸性能，缝合线保持力，耐破裂性和细胞培养也得到了改善，并为血管组织工程应用显示了广阔的前景。