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Cavitary Pulmonary Nodules in an Immunocompromised Patient With Urothelial Carcinoma of the Bladder.
Clinical Infectious Diseases ( IF 11.8 ) Pub Date : 2018-10-30 , DOI: 10.1093/cid/ciy270
Ayana Morales 1 , Usha Mathur-Wagh 1 , Anthony Tran 2 , Isabelle Cui 3 , Robert A DeSimone 3 , Stephen G Jenkins 1, 3 , Lars F Westblade 1, 3 , Sian Jones 1
Affiliation  

A 59-year-old Moroccan man with a history of metastatic urothelial cell carcinoma presented in May 2016 with fever, shortness of breath, and chest pain. Noninvasive urothelial carcinoma had been diagnosed in 2012 and treated with mitomycin. In 2014, the patient had received intravesicular Mycobacterium bovis BCG therapy, but invasive bladder carcinoma subsequently developed, requiring 4 cycles of chemotherapy with methotrexate, vinblastine, doxorubicin, and cisplatin. Nine months before the current admission, the patient underwent a radical cystoprostatectomy with creation of a neobladder. Nonetheless, brain metastases developed, for which he received dexamethasone (4 mg orally, twice daily), and underwent neurosurgical resection 3 months before presentation, followed by whole-brain irradiation. He continued receiving intermittent dexamethasone therapy until his admission to our hospital.

中文翻译:

免疫功能低下的膀胱尿路上皮癌患者中的肺部肺结节。

一名59岁的摩洛哥男子,有转移性尿路上皮细胞癌病史,于2016年5月出现发烧,呼吸急促和胸痛。非侵入性尿路上皮癌已于2012年被诊断出并接受丝裂霉素治疗。2014年,患者接受了膀胱内分枝杆菌卡介苗治疗,但后来发展为浸润性膀胱癌,需要用甲氨蝶呤,长春碱,阿霉素和顺铂进行4个周期的化疗。本次入院前9个月,患者接受了根治性膀胱前列腺切除术并产生了新膀胱。尽管如此,仍发生脑转移,为此他接受了地塞米松(4 mg口服,每天两次),并在就诊前3个月进行了神经外科切除,然后进行了全脑照射。他继续接受间歇性地塞米松治疗,直到他入我们的医院。
更新日期:2018-10-30
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