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Formation and characterization of spray dried coated and uncoated liposomes with encapsulated black carrot extract
Journal of Food Engineering ( IF 5.5 ) Pub Date : 2019-04-01 , DOI: 10.1016/j.jfoodeng.2018.10.025
Burcu Guldiken , Annika Linke , Esra Capanoglu , Dilek Boyacioglu , Reinhard Kohlus , Jochen Weiss , Monika Gibis

Abstract The degradation of black carrot anthocyanins (BCE) under stress conditions as under the effect of a spray drying process was evaluated in different encapsulation systems (extract, chitosan-coated and uncoated liposomes and chitosan-extract-mixture). The encapsulation efficiencies of liposomes prepared by high-pressure homogenization containing 2% lecithin with 0.1%, 0.2%, and 0.4% extract were found as 86.6% ± 16.1%, 82.2% ± 9.7%, and 46.9% ± 6.3%, respectively. The extract-loaded liposomes (0.2% extract) were chosen for liposomes considering further dilutions. The chitosan-coated liposomes were generated with 0.1% chitosan according to their particle size (82.7 ± 1.5 nm) and zeta potential of 51.4 ± 0.6 mV. All samples were found to be physically stable after the spray drying process. In addition, SEM images of the liposomal powder particles showed a uniformly wrinkled surface that would indicate stability of liposomal systems against spray drying. However, the liposomal samples showed lower stability compared to the BCE and BCE-chitosan mixtures according to the biochemical analysis of the reconstituted powders.

中文翻译:

具有包封的黑胡萝卜提取物的喷雾干燥包衣和未包衣脂质体的形成和表征

摘要 在不同的封装系统(提取物、壳聚糖包覆和未包覆的脂质体以及壳聚糖提取物混合物)中评估了在压力条件下以及喷雾干燥过程的影响下黑胡萝卜花青素 (BCE) 的降解。含有2%卵磷脂和0.1%、0.2%和0.4%提取物的高压均质脂质体的包封率分别为86.6%±16.1%、82.2%±9.7%和46.9%±6.3%。考虑进一步稀释,选择负载提取物的脂质体(0​​.2% 提取物)用于脂质体。根据其粒径 (82.7 ± 1.5 nm) 和 51.4 ± 0.6 mV 的 zeta 电位,使用 0.1% 壳聚糖生成壳聚糖涂层脂质体。发现所有样品在喷雾干燥过程后物理稳定。此外,脂质体粉末颗粒的 SEM 图像显示出均匀起皱的表面,这表明脂质体系统对喷雾干燥的稳定性。然而,根据重构粉末的生化分析,与 BCE 和 BCE-壳聚糖混合物相比,脂质体样品显示出较低的稳定性。
更新日期:2019-04-01
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