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Transition Metal‐Free gem‐Difluorocyclopropanation of Alkenes with CF3SiMe3–NaI System: a Recipe for Electron‐Deficient Substrates
Advanced Synthesis & Catalysis ( IF 5.4 ) Pub Date : 2018-10-19 , DOI: 10.1002/adsc.201801304
Pavel S. Nosik 1, 2 , Sergey V. Ryabukhin 2 , Oleksandr O. Grygorenko 1, 2 , Dmitriy M. Volochnyuk 3
Affiliation  

The inside cover picture, provided by Pavel Nosik, Sergey Ryabukhin, Dmitriy Volochnyuk, and Oleksandr Grygorenko illustrates difluorocyclopropanation of electron‐deficient alkenes with CF3SiMe3–NaI system using the “slow addition” protocol. The method is effective for various α,β‐unsaturated esters, which opens an access to difluorocyclopropyl‐substituted carboxylic acids on a multigram scale. Background artwork by Web Design Studio “ZORELiT”. Details can be found in the full paper on pages xxxx–xxxx (P. S. Nosik, S. V. Ryabukhin, O. O. Grygorenko, D. M. Volochnyuk, Adv. Synth. Catal. 2018, 360, xxxx–xxxx; DOI: 10.1002/adsc.201801006).


中文翻译:

CF 3 SiMe 3 -NaI系统的无过渡金属宝石-烯烃的二氟环丙烷化:缺电子衬底的配方

所述内封面图片,由帕维尔Nosik,塞吉Ryabukhin,德米特里Volochnyuk和阿列克Grygorenko提供示出了与CF缺电子烯烃的difluorocyclopropanation 3森达3使用“缓慢加入”协议-NaI系统。该方法对各种α,β-不饱和酯均有效,从而以克数为单位打开了二氟环丙基取代的羧酸的途径。Web Design Studio“ ZORELiT”的背景图稿。细节可以在上页面的全部论文中找到XXXX-XXXX(PS Nosik,SV Ryabukhin,OO Grygorenko,DM Volochnyuk,进阶合成器CATAL。 2018360,为xxxx-xxxx; DOI:10.1002 / adsc.201801006)。
更新日期:2018-10-19
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