The olefin-olefin metathesis reaction has emerged as one of the most important carbon-carbon bond-forming reactions, as illustrated by its wide use in the synthesis of complex molecules, natural products and pharmaceuticals. The corresponding metathesis reaction between carbonyls and olefins or alkynes similarly allows for the formation of carbon-carbon bonds. Although these variants are far less developed and utilized in organic synthesis, they possess attractive qualities that have prompted chemists to incorporate and explore these modes of reactivity in complex molecule synthesis. This review highlights selected examples of carbonyl-olefin and carbonyl-alkyne metathesis reactions in organic synthesis, in particular in the total synthesis of natural products and complex molecules, and provides an overview of current advantages and limitations.

中文翻译：

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超越烯烃：合成的新复分解方向。

烯烃-烯烃复分解反应已成为最重要的碳-碳键形成反应之一，正如它在复杂分子，天然产物和药物的合成中的广泛应用所说明的那样。羰基与烯烃或炔烃之间的相应复分解反应类似地允许形成碳-碳键。尽管这些变体远未开发出来并用于有机合成中，但它们具有吸引人的品质，促使化学家在复杂分子合成中引入并探索了这些反应方式。这篇综述重点介绍了有机合成中，特别是天然产物和复杂分子的全合成中羰基-烯烃和羰基-炔烃复分解反应的选定实例，并概述了当前的优势和局限性。