Oxidase-mimicking nanozymes are attractive since they do not require H₂O₂, but such examples are quite rare. In particular, few can catalyze oxidation of fluorogenic substrates. We herein communicate that NiO nanoparticles are an oxidase nanozyme at physiological pH for fluorogenic Amplex red. Its activity is much higher than that of the commonly used nanoceria. This finding fills an urgent gap for biosensor development and intracellular imaging for the nanozyme field.

中文翻译：

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高活性模拟氧化酶的NiO纳米酶†

模仿氧化酶的纳米酶是有吸引力的，因为它们不需要H ₂ O ₂，但是这种例子很少见。特别是很少有能催化荧光底物的氧化。我们在本文中传达NiO纳米颗粒在荧光pH下对于发荧光的Amplex红是一种氧化酶纳米酶。它的活性远高于常用的纳米氧化铈。这一发现填补了纳米传感器领域生物传感器开发和细胞内成像的紧迫空白。