当前位置: X-MOL 学术J. Am. Acad. Dermatol. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Androgens in women
Journal of the American Academy of Dermatology ( IF 13.8 ) Pub Date : 2018-10-10 , DOI: 10.1016/j.jaad.2018.08.061
Sarah Azarchi , Amanda Bienenfeld , Kristen Lo Sicco , Shari Marchbein , Jerry Shapiro , Arielle R. Nagler

Androgen-mediated cutaneous disorders (AMCDs) in women, including acne, hirsutism, and female pattern hair loss, can be treated with hormone-modulating therapies. In the second article in this Continuing Medical Education series, we discuss the hormone-modulating therapies available to dermatologists for the treatment of AMCDs, including combined oral contraceptives, spironolactone, finasteride, dutasteride, and flutamide. Available hormone-modulating treatments used for each AMCDs are reviewed, along with mechanisms of androgen modulation, safety profile, contraindications, monitoring parameters, and evidence of efficacy. Medications discussed include those that are approved by the US Food and Drug Administration for certain AMCDs and some that are used off-label. Despite the ubiquity of hormone-modulating therapies used for AMCDs, this review highlights the need for more rigorous studies to evaluate these therapies for acne, hirsutism, and female pattern hair loss.



中文翻译:

女性中的雄激素

女性的雄激素介导的皮肤疾病(AMCD),包括痤疮,多毛症和女性脱发,可以通过激素调节疗法进行治疗。在该继续医学教育系列的第二篇文章中,我们讨论了皮肤科医生可用于治疗AMCD的激素调节疗法,包括联合口服避孕药,螺内酯,非那雄胺,度他雄胺和氟他胺。审查了用于每种AMCD的可用激素调节疗法,以及雄激素调节机制,安全性,禁忌症,监测参数和功效证据。所讨论的药物包括经美国食品药品监督管理局批准用于某些AMCD的药物,以及一些不在标签上使用的药物。尽管用于AMCD的激素调节疗法无处不在,

更新日期:2018-10-10
down
wechat
bug