Phytosterols were microencapsulated by spray drying in a shell represented by WPI, inulin and chitosan at four different combinations through the formulation of aqueous suspensions. Moreover, two concentrations of Tween 80 (1.25% and 2.50% w/w) and two inlet temperatures (125 °C and 155 °C) were tested. The effect of the different experimental conditions on the process yield and on the microcapsules properties was evaluated. A significant effect of all variables on the microcapsule properties was found. Accordingly, the best performance, with the maximum loading capacity of 25%, was obtained by using only WPI as shell material, Tween 80 at 1.25% and inlet temperature of 155 °C. The process was successfully scaled-up from laboratory equipment to a semi-technical scale keeping the optimal shell formulation and process conditions.

通过水悬浮液的配制，将植物甾醇通过喷雾干燥以四种不同组合以WPI，菊粉和壳聚糖为代表的壳微囊化。此外，吐温80的两种浓度（1.25％和2.50％w/ w）和两个入口温度（125°C和155°C）。评估了不同实验条件对工艺收率和微胶囊性能的影响。发现所有变量对微胶囊性质的显着影响。因此，通过仅使用WPI作为外壳材料，吐温80为1.25％和进口温度为155°C，可获得最佳性能，最大负​​载能力为25％。该过程已成功地从实验室设备扩大到半技术规模，并保持了最佳的外壳配方和工艺条件。