The genus Cannabis contains specific substances called cannabinoids that are found in high concentrations in the flowers of non-pollinated female plants. Cannabidiol (CBD) and Δ⁹-tetrahydrocannabinol (Δ⁹-THC) are the two main bioactive substances in this group with medicinal potential. However, these substances are found in low concentrations in fresh flowers. The decarboxylation technique can be applied to fresh flowers to promote an increase in the levels of these substances. Extracts with high levels of cannabinoids and without organic solvent residues have high medicinal and cosmetic potential. The purpose of this work was to present the results of cannabinoid extraction using pressurized fluids from two varieties of flowers of the genus Cannabis. The extractions were conducted using pure supercritical carbon dioxide (scCO₂) and with ethanol as a co-solvent, comparing the use of decarboxylation and winterization techniques. The chemical profiles of cannabinoids (CBD, Δ⁹-THC and cannabinol (CBN)) and the essential oils in the extracts and in fresh flowers were analyzed using different chromatographic techniques. The decarboxylation technique employed maximized the levels of the cannabinoids of interest. The Sovová model used in the adjustment of the experimental kinetic extraction curves was adequate and satisfactory.

大麻属包含称为大麻素的特定物质，该物质在未授粉的雌性植物的花朵中含量很高。大麻二酚（CBD）和Δ ⁹ -四氢大麻酚（Δ ⁹ -THC）是这一组具有药用潜力在两个主要的生物活性物质。但是，这些物质在鲜花中的浓度很低。可以将脱羧技术应用于鲜花以促进这些物质含量的增加。大麻素含量高且没有有机溶剂残留的提取物具有很高的药用和美容潜力。这项工作的目的是介绍使用来自两个属的花的加压流体提取大麻素的结果大麻。使用纯超临界二氧化碳（scCO ₂）并以乙醇为助溶剂进行萃取，比较了脱羧技术和防寒技术的使用。大麻素（CBD，Δ的化学型材⁹ -THC和大麻酚（CBN））和在提取物中的精油和在鲜花使用不同的色谱技术进行分析。所采用的脱羧技术使目标大麻素的含量达到最大。用于调整实验动力学提取曲线的Sovová模型是充分且令人满意的。