The difluoroalkylation of unactivated benzo[d]isoxazoles with ethyl difluorobromoacetate by visible-light photoredox catalysis via direct and regioselective CH functionalization has been efficiently achieved under mild reaction conditions. The difluoroalkylated adducts could be readily converted to a variety of corresponding CF₂-containing heterocycles, demonstrating the synthetic utility of the present approach.

中文翻译：

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通过直接和区域选择性的C H官能团在可见光下诱导3-取代的苯并[ d ]异恶唑的光催化二氟烷基化

在温和的反应条件下，通过直接和区域选择性的C H官能团通过可见光光氧化还原催化有效地实现了未活化的苯并[ d ]异恶唑与二氟溴乙酸乙酯的二氟烷基化。二氟烷基化的加合物可以容易地转化成各种相应的含CF ₂的杂环，证明了本方法的合成效用。